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A 52-Month Summary of Results Using Calcium Hydroxylapatite for Facial Soft Tissue Augmentation
This retrospective clinical review conducted by Thomas L. Tzikas, MD, documented the safety and effectiveness of Radiesse dermal filler in treatment of nasolabial folds, marionette lines, and other areas of the face. Over a 52 month period, from October 2002 to January 2007, Radiesse filler was injected in 1,000 patients (886 women and 114 men, ranging in age from 21 to 85 years) for a variety of facial aesthetic applications. The nasolabial folds were the most frequently treated site, followed by the marionette lines/oral commissures.
The clinical review found a high satisfaction rate with Radiesse dermal filler treatment, with most patients experiencing at least 80% persistence of effect at 1-year follow-up without retreatment, independent of the area of the face where treatment was received.
In conclusion, the author stated, "Radiesse was well tolerated over the
4 years of use described here. Adverse events were minor, and most resolved
without treatment. No product-related serious adverse events were reported.
Some patients experienced minor effects, such as redness, swelling,
itching, and bruising, which are commonly seen with any injectable
material, including collagen and hyaluronic acid."
The study abstract is available at http://www.blackwell-synergy.com/doi/abs/10.1111/j.1524-4725.2008.34237.x
An Investigation of Changes in Physical Properties of Injectable
Calcium Hydroxylapatite in a Carrier Gel
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