Navigation Links
Quick microchip test for dangerous antibiotic resistant bacteria
Date:9/4/2007

Researchers at the Veterinary Laboratories Agency in Surrey have developed microchips capable of quickly and cheaply identifying dangerous and drug resistant bacteria in clinical samples, scientists announced today (Wednesday 5 September 2007) at the Society for General Microbiology's 161st Meeting at the University of Edinburgh, UK, which runs from 3-6 September 2007.

For the first time doctors and veterinarians will be able to test clinical samples from their patients for the presence of the genes for antibiotic resistance in bacteria, getting the results within 24 hours instead of having to wait for as much as a week.

"We have developed a test chip which can accurately identify 56 virulence genes in the diarrhoea-causing Escherichia coli bacteria and 54 antimicrobial resistance genes covering all the known families of gram-negative bacteria", says Dr Muna Anjum from the UKs Veterinary Laboratories Agency in Addlestone, Surrey.

The chip will speed up the process of diagnosis and treatment by giving quicker results from clinical testing laboratories. The chip will also make it possible to carry out routine surveillance studies to monitor the way genes for virulence and antimicrobial resistance are spread in the environment, food samples, or even in farm and wild animals.

"Our chips have already been used very successfully in a survey of microbial resistance in human clinical isolates, foods, farm animals and also in wild animals, where we were looking at them as possible reservoirs of infection which can transmit disease back into farm animals", says Dr Anjum.

The miniaturised microarray chips were developed by studying and identifying the dangerous genes from samples of gut bacteria including the diarrhoea-causing E. coli bacteria and the food poisoning bug Salmonella.

In a test of the new chip screening technique, the most common antibiotic resistance gene was identified in 90% of E. coli and 56% of Salmonella bacteria from a random group of animal and human clinical samples. The tests even identified some unique and previously unknown combinations of virulence genes, whose significance still needs to be determined.

"In the near future, we are planning to automate the method to enable each sample to be tested for up to 600 genes and for 96 samples to be processed in half a day", says Dr Muna Anjum. "This will allow large scale monitoring of bacterial pathogens to see how they gain and lose genes related to disease and its control".

This technology will also allow scientists to search for and identify important genes from other pathogens and bacteria, for instance genes which may be commercially important in industrial processes such as waste handling, plastics production, manufacturing, food processing or pharmaceutical development.


'/>"/>
Contact: Lucy Goodchild
l.goodchild@sgm.ac.uk
44-011-898-81843
Society for General Microbiology
Source:Eurekalert

Related biology technology :

1. Mastercycler Gradient Quick Programming Guide
2. QIAquick PCR Purification Kit
3. QuickLane 24 - 48 Hour Sequencing
4. QuickLyse Miniprep Kit
5. Quick peeks, Clawback Agreements, and the rules of electronic discovery
6. EraGen diagnostic passes UW tests, could quickly detect bird flu
7. Quick response manufacturing and biotech
8. Fiserv Credit Processing Selects System To Keep Transactions Quick
9. High sensitivity quantitation of metabolites of nitrofuran antibiotics in animal tissue using LC/MS/MS
10. WARF Granted New Antibiotics Patent
11. Oshkosh Truck spends $4.8 million on disaster-resistant network
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/12/2017)... ... October 12, 2017 , ... ... of a complex biological network, a depiction of a system of linkages and ... Dmitry Korkin, PhD, associate professor of computer science at Worcester Polytechnic Institute (WPI) ...
(Date:10/12/2017)... , ... October 12, 2017 , ... ... Vilnius, Lithuania, announced today that they have entered into a multiyear collaboration to ... provide CRISPR researchers with additional tools for gene editing across all applications. , ...
(Date:10/12/2017)... ... October 12, 2017 , ... ... with the addition of its newest module, US Hemostats & Sealants. , SmartTRAK’s ... hemostats, absorbable hemostats, fibrin sealants, synthetic sealants and biologic sealants used in surgical ...
(Date:10/12/2017)... ... October 12, 2017 , ... ... analysis platform specifically designed for life science researchers to analyze and interpret ... Rosalind Franklin, who made a major contribution to the discovery of the ...
Breaking Biology Technology:
(Date:4/5/2017)... Allen Institute for Cell Science today announces the launch ... dynamic digital window into the human cell. The website ... deep learning to create predictive models of cell organization, ... suite of powerful tools. The Allen Cell Explorer will ... resources created and shared by the Allen Institute for ...
(Date:4/4/2017)...   EyeLock LLC , a leader of iris-based ... Patent and Trademark Office (USPTO) has issued U.S. Patent ... an iris image with a face image acquired in ... 45 th issued patent. "The ... the multi-modal biometric capabilities that have recently come to ...
(Date:3/30/2017)... HONG KONG , March 30, 2017 ... developed a system for three-dimensional (3D) fingerprint identification by adopting ground ... technology into a new realm of speed and accuracy for use ... applications at an affordable cost. ... ...
Breaking Biology News(10 mins):