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QIAGEN and Max Planck Institute for Infection Biology Collaborate to Develop Assay for Active TB Risk in Individuals With Latent Infection
Date:1/9/2012

developing countries, global travel and immigration render TB a problem for the whole world," said Professor Stefan H.E. Kaufmann, Director of the Department of Immunology at the MPIIB in Berlin. "We believe QIAGEN, as a leader in infectious disease testing, is the right choice to help us reach new scientific achievements and jointly improve previously inadequate preventive, diagnostic and therapeutic tools for TB. Through this collaboration we will gain access to important technologies and concomitantly strengthen the further development of our vaccine program."

The Department of Immunology at the MPIIB is performing pioneering research on infectious diseases that threaten global health. One major project includes development of a vaccine against TB in combination with the definition of biomarkers to reliably distinguish between latent and active TB. "Results from this research may accelerate clinical trials of TB vaccines. Identification of biomarkers that can predict risk of active TB disease in individuals with latent TB will also be able to predict protective efficacy of a vaccine candidate early in clinical trial", explains Prof. Stefan H.E. Kaufmann.

About Tuberculosis:

Although TB is an ancient infectious disease, it is still a global health threat with high morbidity and 1.4 million deaths worldwide, annually.[*] TB is caused by the bacterial pathogen Mycobacterium tuberculosis and usually affects the lung. In most infected individuals, the pathogen is contained and therefore causes latent infection. According to the World Health Organization (WHO), nearly one-third of the world's population is infected by M. tuberculosis, and 5-10% of infected persons develop active disease during their lifetime if they are not treated. Although diagnosis of active TB holds the most potential for containing the risk of infection, the WHO estimates that less than 60% of all active TB cases are identified.
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