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Pyratine-6(TM) Study Published in Journal of Drugs in Dermatology
Date:2/26/2008

matopharmacology. During his academic career he has effectively combined his expertise in pharmacology to the basic and clinical areas of dermatology. His work in dermatopharmacology has focused on the skin barrier properties and topical delivery of drugs. He has worked extensively with pharmaceutical companies in the development of effective topical drug delivery systems and has written over 40 IND applications for testing new topical therapies for skin disorders. His work is unique, in that drug development is taken from formulation testing in vitro to studies in experimental models, and finally to clinical testing in patients.

Dr. McCullough joined the faculty of the Department of Dermatology of the University of California, Irvine School of Medicine in 1979, where he is currently a Professor of Dermatology and Director of the Dermatology Clinical Research Center. Dr. McCullough earned his Bachelor of Science degree in chemistry from Indiana University and his Ph.D. in pharmacology from Yale University.

About Senetek PLC

Senetek PLC (OTCBB: SNKTY) is a Life Sciences company engaged in the development of breakthrough technologies that target the science of healthy aging. The Company's extensive research collaborations have resulted in a strong pipeline of patented compounds and products with broad therapeutic applications and a leading presence in dermatology. Senetek collaborates with established specialty pharmaceutical companies in the final development and marketing of its proprietary products, most recently resulting in the development of the best-selling anti-aging product sold in the North American physician market.

For more information, visit the company's website at http://www.senetekplc.com.

This news release contains statements that may be considered 'forward-looking statements' within the meaning of the Private Securities Litigation Reform Act. Forward-looking stat
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