Navigation Links
Putting a bull's-eye on the flu: Detailing influenza's structure for drug targeting
Date:10/21/2010

nior author of the paper.

The magnet allows the team to use a technique called solid-state nuclear magnetic resonance which utilizes some of the underlying technology of an MRI to map the structure of the channel. Florida State's Huan-Xiang Zhou and his students used the data from the NMR to compute precise readings of the distance between two molecules or atoms.

"Now we have a much more refined view of M2, all the way down to the atomic level, the level that includes protons going through the channel, to draw conclusions about how to block it," said Busath.

Busath runs tests to ensure that the samples being studied behave in the same way as viruses in real cells, which demonstrate that the experimental conditions have preserved the study's relevance to the real world.

This new study is more precise than previous work because it examines the virus in an environment that closely simulates its native setting. This is particularly important because its structure can change significantly based on its surroundings.

Now the research team has started screening millions of compounds, looking for drugs that will bind to the channel and block it in its reproductive role.


'/>"/>

Contact: Joseph Hadfield
joseph_hadfield@byu.edu
801-422-9206
Brigham Young University
Source:Eurekalert  

Page: 1 2

Related biology technology :

1. Researchers putting a freeze on oscillator vibrations
2. Putting the squeeze on an old material could lead to instant on electronic memory
3. Putting a new spin on current research
4. Intricate, curving 3-D nanostructures created using capillary action forces
5. New computer-tomography method visualizes nano-structure of bones
6. High-speed filter uses electrified nanostructures to purify water at low cost
7. Federal grant invests in nanostructured super materials
8. Unprecedented look at oxide interfaces reveals unexpected structures on atomic scale
9. Empa grows sea urchin-shaped structures
10. Depth charge: Using atomic force microscopy to study subsurface structures
11. Researchers use X-ray diffraction microscope to reveal 3-D internal structure of whole cell
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Putting a bull's-eye on the flu: Detailing influenza's structure for drug targeting
(Date:12/19/2014)... 18, 2014 Egenix, Inc. is pleased to announce ... of the Board, to succeed Donald Fresne ; Mr. ... continue as a member of the Board.  In recognition of ... the company over almost twenty years, the Board designated Mr. ... Directors has established a Search Committee to find a suitable ...
(Date:12/17/2014)... 16, 2014 The Activated Carbon ... which is why IBISWorld updated its original industry research ... benefit from an intensified focus on environmental policy. Over ... emission standards for power plants and a range of ... IBISWorld Industry Analyst Sarah Kahn, “a range of downstream ...
(Date:12/17/2014)... 17, 2014 Achim Noack has been ... Stoller Group. In this position, Noack will assist Jerry ... matters, develop marketing strategy and supervise global marketing management ... “Achim has tremendous knowledge and experience in the crop ... “His experience and innovative thinking will be a great ...
(Date:12/17/2014)... This report is a professional ... For an overview analysis, the report introduces quartz ... structure, industry overview, policy analysis, and news analysis, ... has witnessed rapid development with key manufacturers increasing ... report mentions quartz tubing upstream raw materials and ...
Breaking Biology Technology:Activated Carbon Manufacturing in the US Industry Market Research Report Has Been Updated from IBISWorld 2Activated Carbon Manufacturing in the US Industry Market Research Report Has Been Updated from IBISWorld 3Achim Noack Joins Stoller Group as Global Vice President of Marketing and Administration 22020 Quartz Tubing Market: Global Development & Forecasts Analysis Now at DeepResearchReports.com 2
... Growth Plans, Technology Leadership, INDIANAPOLIS, Feb. 12 ... wholly owned subsidiary of The Dow Chemical,Company (NYSE: ... presentation made to investors,earlier today by Jerome Peribere, ... at the Goldman Sachs Agricultural Chemicals,Conference in New ...
... CBM ) announced that it will release fourth quarter and,full ... (Logo: http://www.newscom.com/cgi-bin/prnh/20000613/CAMBREXLOGO ), The Company will host ... financial results., ... and Full Year 2007 Earnings Conference Call, When: ...
... ANN ARBOR, Mich., Feb. 12 New Enterprise,Forum will ... entrepreneurs,in conjunction with its annual awards presentations. The event ... the Holiday Inn North Campus on,3600 Plymouth Road in ... be given to entrepreneurs in the following,categories: Best New ...
Cached Biology Technology:Dow AgroSciences' Success Presented to Wall Street 2New Enterprise Forum Celebrates 22nd Anniversary, Presents Annual Entrepreneur Awards to Randal Charlton & Others 2
(Date:12/4/2014)... Dec. 3, 2014  Crossmatch™, a leading provider ... its DigitalPersona ® Pro Enterprise software and ... deployed throughout First Bank branch locations in ... Carolina and Virginia. First Bank, a progressive ... Pines, North Carolina , selected the Crossmatch ...
(Date:12/3/2014)... GLENDALE, Ariz. , Dec. 2, 2014 ... biometric hand readers, Inception Technologies is pleased to announce ... it easier for customers to collect the workforce data ... the problems that have been left by existing readers. ... to user interface, connectivity and modern technology. Older models ...
(Date:11/21/2014)... -- Earlier this year Donald Spector , Chairman of ... the most prolific inventors in the world, got a ... to third party agencies. Spector envisioned this technology even ... earliest known patents in this area. Now major technology ... care, elder care and hospital applications. This technology has ...
Breaking Biology News(10 mins):First Bank Partners with Crossmatch to Increase Log In Security 2First Bank Partners with Crossmatch to Increase Log In Security 3Inception Technologies to Release New Biometric Reader 2Patented Biosensor Wearable Technology Provides a More Civilized Method of Quarantine 2Patented Biosensor Wearable Technology Provides a More Civilized Method of Quarantine 3Patented Biosensor Wearable Technology Provides a More Civilized Method of Quarantine 4
... NY) Albert Einstein College of Medicine of Yeshiva University ... (NIH) Nathan Shock Centers of Excellence in the Basic Biology ... leadership in the pursuit of basic research into the biology ... from the NIH,s National Institute on Aging. "Einstein has ...
... discovery about selective serotonin reuptake inhibitors (SSRIs) suggests that ... disorders like depression and anxiety, have multiple effects on ... August 2010 issue of GENETICS ( http://www.genetics.org ... targets or pathways affected by SSRIs. Such secondary pathways ...
... A UCSF-led team has discovered at least one key ... genetic mutations that can lead to adult leukemia. Their finding ... disorders develop. The study, reported in " Cell Stem ... Stem Cell and Cell , opens a new ...
Cached Biology News:Einstein designated an NIH Center of Excellence for aging research 2Einstein designated an NIH Center of Excellence for aging research 3Einstein designated an NIH Center of Excellence for aging research 4SSRIs may pack more punch at the cellular level than believed 2Blood stem cell, leukemia link illuminated in UCSF-led study 2Blood stem cell, leukemia link illuminated in UCSF-led study 3
... The BAS-2500 is ... applications: Molecular Biology (1D ... protein blots, Macroarrays); Pharmacokinetics ... autoradiography, thin layer chromatography); ...
... This microscope is described by end-users ... it incorporates the fundamentals of light microscopy ... and small footprint, it does not require ... in a busy lab environment. The DM-BA300 ...
... BAS-5000 is the highest resolution standard ... top member of Fujifilm's family of ... Imaging Plate (IP) and changeable resolutions ... Fujifilm BAS-5000 does it without compromising ...
This bispecific antibody complex has been tested for efficient depletion of CD41+ cells using the StemSep ; negative immunomagnetic cell separation system....
Biology Products: