Navigation Links
Publication of Shire plc's Annual Report 2008
Date:3/25/2009

rom the lower price jurisdiction to the higher price jurisdiction. If the parallel importation of lower priced drugs is permitted in the US, it could have the effect of reducing sales of equivalent drugs in the US. To the extent that parallel importation increases, the Group may receive less revenue and earnings from its commercialized products. The parallel importation of prescription drugs is relatively common within the EU.

A disruption to the product supply chain may result in the Group being unable to continue marketing or developing a product or may result in the Group being unable to do so on a commercially viable basis

The Group sources its products from third party contract manufacturers, and for certain products has its own manufacturing capability. In the event of either the Group's failure or the failure of any third party contract manufacturer to comply with mandatory manufacturing standards (often referred to as 'Current Good Manufacturing Standards' or cGMP) in the countries in which the Group intends to sell or have its products sold, the Group may experience a delay in supply or be unable to market or develop its products.

The Group dual-sources certain key products and/or active ingredients. However, the Group currently relies on a single source for production of the final drug product for each of DAYTRANA, FIRAZYR, LIALDA, PENTASA, REMINYL and XAGRID and relies on a single active ingredient source for each of ELAPRASE, FIRAZYR, FOSRENOL, REMINYL, REPLAGAL and XAGRID.

In the event of financial failure of a third party contract manufacturer, the Group may experience a delay in supply or be unable to market or develop its products. This could have a material adverse affect on the Group's financial condition and results of operations.

There is no assurance that suppliers will continue to supply on commercially viable terms, or be able to supply components that m
'/>"/>

SOURCE Shire Plc
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33

Related biology technology :

1. Bionovo Announces Publication of Positive Phase 2 Trial Results for Menerba(TM)
2. Sopherion Therapeutics, LLC Announces Publication of Phase I/II Myocet(R) (Nonpegylated Liposomal Doxorubicin) Data in Advanced Breast Cancer Patients
3. InVitria Among Leading Innovators in Cell Culture Media According to Top Biotechnology Publication
4. BioTrends Releases TreatmentTrends(TM): US Nephrology, an Ongoing Syndicated Publication Providing Insight into Physician Perceptions and Management of Renal Anemia, Hyperphosphatemia, and Secondary Hyperparathyroidism
5. New Publications Show Noninvasive Magnetic Resonance-Guided Focused Ultrasound to be a Potentially Safe, Effective Pain-Relieving Treatment for Bone Metastases
6. PharmSource and BioProcess Technology Consultants Announce Publication of New Market Report: Cell Culture Manufacturing Capacity: Trends and Outlook through 2013
7. Webcast Alert: Regulus Therapeutics, Alnylam Pharmaceuticals and Isis Pharmaceuticals Announce New Nature Publication on miR-21 Conference Call
8. Genomic Health Announces Publication of a Study Demonstrating the Oncotype DX(R) Breast Cancer Assay Influences Chemotherapy Treatment Recommendation in 44 Percent of Patients Evaluated
9. Publication on Tregitopes in Blood Journal of October 2008
10. Repligen Announces Publication of Positive Results with Proprietary HDAC Inhibitor in Huntingtons Disease Model
11. ABMAC Foundation Announces Publication of an Historic Volume Documenting the Creation of a National Health Care System in Taiwan
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/15/2014)... (PRWEB) January 15, 2014 DTS Language ... its Online Web Portal for Life Science organizations who need ... specify the subject matter of their documents in advance with ... help reduce time-to-delivery of translations, often a critical factor in ...
(Date:1/15/2014)... 2014 AudioNotch is the internet's leading ... the treatment of tinnitus. Patients listen to sound therapy ... a period of weeks to months, their tinnitus volume decreases. ... forms: Notched Music and Notched White Noise. Now, AudioNotch is ...
(Date:1/14/2014)... Washington, DC (PRWEB) January 14, 2014 ... session for Thursday, January 23, 2014 at 2pm EST ... Actionable Knowledge.” The topic focuses on how technology can ... mission critical decisions for government agencies. The online webinar ...
(Date:1/14/2014)... As pet owners drew up their lists of New Year,s resolutions ... care of my furry companion." Nowadays there are pet salons, dog ... to take the little canine or feline darlings along wherever mommy ... some pricey toys at the pet store. But anyone who has ...
Breaking Biology Technology:DTS Improves Efficiency for Life Science Document Translations 2Webcast - Natural Language Processing: Converting Raw Data into Actionable Knowledge – Hosted by Carahsoft and CDS Federal Services 2New Year's Resolution: Give Pets the Gift of Top-Notch Health Care 2
... from MedImmune Inc., Elliott Sigal, M.D., Ph.D, from Bristol-Myers Squibb ... ... May 7 IBC Life Sciences announced,the keynote line up ... World Congress, to take place August 4-7, 2008 in,Boston, MA. ...
... The Annual,General Meeting of Arpida Ltd (SWX: ARPN) ... Board of Directors., A total of 73 shareholders ... today. 6,186,266 shares were represented, or 29.3% of the ... were on the agenda., 1. Approval of the ...
... May 7 Champions,Biotechnology, Inc. (OTC Bulletin ... of advanced preclinical platforms and tumor specific ... today announced that it has,established an agreement ... of certain therapeutic antibodies in ImClone,s,clinical development ...
Cached Biology Technology:Innovative and Forward-Thinking Experts to Deliver Keynote Presentations at IBC's 13th Annual Drug Discovery & Development of Innovative Therapeutics World Congress 2Arpida Annual General Meeting of Shareholders Approves All Board Proposals 2Champions Biotechnology and ImClone Systems Establish Agreement for Preclinical Evaluation of Oncology Drugs 2Champions Biotechnology and ImClone Systems Establish Agreement for Preclinical Evaluation of Oncology Drugs 3
(Date:7/10/2014)... control everyday household items such as washing machines could ... a new study has claimed., As part of an ... mathematicians, including those from the University of Exeter, have ... be replicated in the natural world to help restock ... - in essence a built-in feedback control mechanism to ...
(Date:7/10/2014)... is ranked amongst the top 100 worst global invasive species ... new study published in the open access journal ... of the introduction of the yellow crazy ant to the ... de Mai, a UNESCO World Heritage Site, on the Seychelles. ... unique ecosystem containing many endemic species, including the iconic coco ...
(Date:7/9/2014)... of protein, that,s not why the Millennials are eating it, ... Club Inc.,s annual International Recognition Days convention July 10th in ... want dishes that are quick, easy to cook and that ... care less about any health benefits of Tofu," said lead ... and because it,s quick to cook and it,s filling.", The ...
Breaking Biology News(10 mins):Feedback control could be key to robust conservation management 2Invasion of yellow crazy ant in a Seychelles UNESCO palm forest: Threats and solutions 2
... Assassin bugs, so named because these insects lie in ambush ... found all over the world. Nearly 140 species of these ... mouth, they are also called kissing bugs. All kissing ... disease that imposes an economic burden on society. Surprising, ...
... ocean distribution of populations of phytoplankton, tiny organisms that could ... this week,s online journal Science Express, researchers show ... will cause populations of these marine microorganisms to thrive near ... tropical oceans, we are predicting a 40 percent drop in ...
... PARK, Pa. -- Had a bad day? Extending your ... the solution, according to Penn State researchers, who found ... when they exercised more than usual. "We found ... their daily physical activity," said Jaclyn Maher, graduate student ...
Cached Biology News:A clearer picture of how assassin bugs evolved 2A clearer picture of how assassin bugs evolved 3Small marine organisms' big changes could affect world climate 2Exercise boosts satisfaction with life, researchers find 2
BD Falcon, microtest ELISA plate 96 well flat-bottom, clear. Polystyrene, nonsterile, no lid (25/sp, 100/ca) Packaging: 25 / pack, 100 / case ...
... The Chemicon Detergent-OUT Kit is a ... from protein solutions. Removes detergents without ... load the protein solution on the Detergent-OUT ... solution. Micro columns are suitable for removing ...
... is a simple high performance method for ... detergents without significant dilution of protein solution. ... the Detergent-OUT Spin column and collect detergent ... suitable for removing detergent from a maximum ...
... microarrays are derived from frozen embedded tissue ... control procedures to ensure the highest quality. ... in one block, sectioned at a thickness ... slides. Sections are large (3-5 mm in ...
Biology Products: