Navigation Links
Publication of Shire plc's Annual Report 2008
Date:3/25/2009

if government regulation is stricter for the Group's new products than for existing treatments; - if the new products suffer a loss of patent protection or competitors successfully challenge or circumvent the Group's patents or regulatory exclusivity; - if planned geographical expansion into emerging markets is not successful; or - if the size of the patient population for the new product is less than expected or the Group fails to identify new patients for the new products.

If the Group is unable to commercialize ELAPRASE, VYVANSE, LIALDA, FIRAZYR, FOSRENOL (ROW) or any of its new products successfully, there may be a material adverse effect on the Group's revenues, financial condition and results of operations.

Any decrease in the combined sales of VYVANSE and ADDERALL XR will significantly reduce revenues and earnings

In 2008, the combined sales of VYVANSE and ADDERALL XR were $1,420.6 million, representing approximately 47% of the Group's total revenues. Sales of ADDERALL XR are expected to decrease significantly due to generic competition that is anticipated to commence on April 1, 2009. Any factors that decrease the sales of ADDERALL XR more significantly than expected could have a material adverse effect on the Group's financial condition and results of operations. In addition, the entrance of generic competitors for ADDERALL XR or other leading attention deficit and hyperactivity disorder ('ADHD') medications could impact the sales of VYVANSE. Other factors that could impact the sales of VYVANSE or ADDERALL XR include, but are not limited to:

    - faster than anticipated erosion of ADDERALL XR sales by
      generic competitors;

    - the development and marketing of competitive pharmaceuticals to VYVANSE
      and ADDERALL XR;

    - issues impacting the production of VYVANSE or ADDERALL XR or the supply
      of 
'/>"/>
SOURCE Shire Plc
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33

Related biology technology :

1. Bionovo Announces Publication of Positive Phase 2 Trial Results for Menerba(TM)
2. Sopherion Therapeutics, LLC Announces Publication of Phase I/II Myocet(R) (Nonpegylated Liposomal Doxorubicin) Data in Advanced Breast Cancer Patients
3. InVitria Among Leading Innovators in Cell Culture Media According to Top Biotechnology Publication
4. BioTrends Releases TreatmentTrends(TM): US Nephrology, an Ongoing Syndicated Publication Providing Insight into Physician Perceptions and Management of Renal Anemia, Hyperphosphatemia, and Secondary Hyperparathyroidism
5. New Publications Show Noninvasive Magnetic Resonance-Guided Focused Ultrasound to be a Potentially Safe, Effective Pain-Relieving Treatment for Bone Metastases
6. PharmSource and BioProcess Technology Consultants Announce Publication of New Market Report: Cell Culture Manufacturing Capacity: Trends and Outlook through 2013
7. Webcast Alert: Regulus Therapeutics, Alnylam Pharmaceuticals and Isis Pharmaceuticals Announce New Nature Publication on miR-21 Conference Call
8. Genomic Health Announces Publication of a Study Demonstrating the Oncotype DX(R) Breast Cancer Assay Influences Chemotherapy Treatment Recommendation in 44 Percent of Patients Evaluated
9. Publication on Tregitopes in Blood Journal of October 2008
10. Repligen Announces Publication of Positive Results with Proprietary HDAC Inhibitor in Huntingtons Disease Model
11. ABMAC Foundation Announces Publication of an Historic Volume Documenting the Creation of a National Health Care System in Taiwan
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/29/2014)... Burnt Hills, NY (PRWEB) August 29, 2014 ... at Burnt Hills Veterinary Hospital are seeking candidates to ... for dogs with osteoarthritis. The ultimate goal of ... of donor stem cells into one or two arthritically ... the treated joints. , Candidates for the current ...
(Date:8/29/2014)... August 29, 2014 Intrinsic Imaging, ... certified, GAMP® 5 compliant imaging core lab, announced ... Phase II clinical trial to assess a new ... this trial, Intrinsic Imaging will provide comprehensive imaging ... protocol and charter development, site qualification, site training ...
(Date:8/28/2014)... “This kit has an improved extraction efficiency and provides users ... said Mark Tess, PhD, Mycotoxin Product Manager for Charm Sciences. ... USDA-GIPSA inspection agencies that have a need to detect aflatoxin ... a matter of minutes with nothing but our equipment and ... grain before accepting it, but they no longer have to ...
(Date:8/28/2014)... PA (PRWEB) August 28, 2014 The ... create a culture that will allow individuals to perform ... becoming increasingly important for employers looking to compete in ... industries are embracing this trend, as the sector increasingly ... of a company, which will have real results on ...
Breaking Biology Technology:Burnt Hills Veterinary Hospital Seeks Candidates for an Investigational Study of Stem Cells for Dogs with Arthritis 2Intrinsic Imaging Awarded Phase II Clinical Trial to Assess New Treatment for Non-Hodgkin’s Lymphoma 2Klein Hersh International Leads Philadelphia Area Life Science Industry in Company Culture 2Klein Hersh International Leads Philadelphia Area Life Science Industry in Company Culture 3
... - Companies that operate in the clean technology industry ... soon will have the opportunity to impress the 600 investors ... Capital Forum in San Francisco. , , Orion Energy ... Madison are among 20 emerging clean technology companies that will ...
... fellow travelers a thing or two about commuting. , ,The ... an executive-in-residence and one of its portfolio companies, Caden ... , Gregg Fergus And since Fergus has been ... his new posts reduce the distance between home and work. ...
... a judge for an industry award contest. It wasn't the Oscars. ... conference room at the Sheraton at Los Angeles International Airport ... of this year's Medical Design Excellence Awards (MDEA). , ... MDEA winners may very well save your life some day. , ...
Cached Biology Technology:Biotech executive books a career flight that's closer to home 2Biotech executive books a career flight that's closer to home 3And the winners in medical design are 2And the winners in medical design are 3And the winners in medical design are 4And the winners in medical design are 5And the winners in medical design are 6
(Date:8/29/2014)... USA - The rise of the Tibetan plateau -- ... -- is important for both its profound effect on ... study published in GSA Bulletin , Katharine Huntington ... isotope thermometry -- using modern and fossil snail shells ... in southwestern Tibet. , Views range widely on ...
(Date:8/28/2014)... bacterial culprits that may drive inflammatory bowel diseases (IBD) ... own intestinal immune responses as a guide. , The ... Cell . , Trillions of bacteria exist within the ... the development and progression of IBD. Yet it,s thought ... a person,s susceptibility to IBD and its potential severity. ...
(Date:8/28/2014)... neighbors than traditional cigarettes, but still release toxins ... from USC. , Scientists studying secondhand smoke from ... to harmful particles, with close-to-zero exposure to organic ... metals in second-hand e-cigarette smoke were found to ... high levels of polycyclic aromatic hydrocarbons cancer-causing ...
Breaking Biology News(10 mins):Snails tell of the rise and fall of the Tibetan Plateau 2Snails tell of the rise and fall of the Tibetan Plateau 3Snails tell of the rise and fall of the Tibetan Plateau 4Snails tell of the rise and fall of the Tibetan Plateau 5Snails tell of the rise and fall of the Tibetan Plateau 6Snails tell of the rise and fall of the Tibetan Plateau 7Yale study identifies possible bacterial drivers of IBD 2Second-hand e-cig smoke compared to regular cigarette smoke 2
... a common genetic disorder previously linked to lung disease ... lung cancer, according to a report in the May ... the JAMA/Archives journals. The disorder, alpha1-antitrypsin deficiency (1ATD), ... the U.S. population and especially those of European descent, ...
... NEW YORK (May 23, 2008) A study led ... Columbia University Medical Center/NewYork-Presbyterian and chairman of the Cardiovascular ... were administered the direct thrombin inhibitor bivalirudin during primary ... a lower rate of major bleeding, and a lower ...
... Institute of Pacific Islands Forestry have submitted a proposal ... of strawberry guava, a South American tree that has ... introduced in 1825 as a garden plant. The scientists ... Land and Natural Resources, and Hawai Department of Agriculture, ...
Cached Biology News:Genetic mutation associated with increased risk of lung cancer 2Findings released from 1 of the largest percutaneous coronary intervention trials ever 2Insect release proposed to control exotic strawberry guava 2
Request Info...
... the consumable measurement plate for ... individually controlled measurement sites. Each ... liquid flow channel system that ... solution and compound applications necessary ...
... application capable of dynamic scheduling, is designed ... lab automation workcells easy for lab personnel, ... programmers. • Users create methods ... you can build a flowchart, you can ...
... to grow, the need for greater detection ... necessary, especially when discerning very similar or ... Confocal Microscope System gives you a level ... available in conventional confocal systems, with detectors ...
Biology Products: