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Proteolix's Carfilzomib Receives Orphan Drug Designation for Treatment of Multiple Myeloma
Date:4/2/2008

ns by inhibiting the proteasome and thereby disrupting protein turnover in cells. Phase 1 clinical studies with carfilzomib, the Company's lead product, have shown that patients with hematologic malignancies who have relapsed or progressed following multiple therapies can achieve durable anti-tumor responses. Carfilzomib is currently in Phase 2 clinical studies to evaluate its safety and efficacy in multiple myeloma, lymphoma and solid tumor malignancies. Proteolix is also developing a pipeline of next-generation proteasome inhibitors, including an oral proteasome inhibitor and a selective immunoproteasome inhibitor. For more information, please visit the Company's website at http://www.proteolix.com.

Contact information:

Matthew Ferguson

investors@proteolix.com

650-266-2825


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SOURCE Proteolix, Inc.
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