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Proteolix Presents Preclinical Data for Oral Proteasome Inhibitor PR-047 at the 50th Annual Meeting of the American Society of Hematology
Date:12/8/2008

Bennett, Ph.D., Vice President of Research at Proteolix. "An effective and tolerable oral proteasome inhibitor would have the potential to provide the clinical benefits of intravenous proteasome inhibitors with added patient convenience and dosing flexibility. With these positive preclinical results in hand, we look forward to advancing PR-047 into clinical trials."

About Proteolix

Founded in December 2003, Proteolix, Inc. is a privately-held biopharmaceutical company, headquartered in South San Francisco, dedicated to discovering, developing and commercializing novel therapeutics that target protein degradation pathways for cancer and autoimmune diseases. Proteolix's lead product, carfilzomib, is the first in a new class of highly specific proteasome inhibitors, and is currently in multiple Phase 2 clinical studies to evaluate its safety and efficacy in hematologic and solid tumor malignancies. Proteolix is also developing a pipeline of novel proteasome inhibitors, including an oral proteasome inhibitor (PR-047) and a selective immunoproteasome inhibitor. For additional information on Proteolix, please visit www.proteolix.com.

    Contact information
    Investors:                          Media Inquiries:
    Matthew Ferguson                    BCC Partners
    Chief Financial Officer             Karen L. Bergman or Michelle Corral
    650-266-2825                        650-575-1509 or 415-794-8662
    investors@proteolix.com


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