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Promising Data Presented on GenVec Malaria Program
Date:11/14/2012

GAITHERSBURG, Md., Nov. 14, 2012 /PRNewswire/ -- GenVec, Inc. (Nasdaq: GNVC) announced today that data were presented on GenVec's malaria vaccine program at the American Society of Tropical Medicine and Hygiene (ASTMH) 61st Annual Meeting, which took take place in Atlanta, Georgia on November 11-15, 2012.           

Data presented at the conference highlighted GenVec's success in identifying novel antigens for use in its malarial vaccine development program. Using a proprietary screening technology, GenVec identified new antigens that are as protective as the gold standard: circumsporozoite protein, or CSP, in an industry-accepted mouse model of malaria.  Recent data suggest that new antigens are needed and that CSP, used in vaccines being developed by others, may not be sufficient to generate a protective response in an adequate percentage of people. 

Data presented at the conference also highlighted GenVec's proprietary non-human primate adenoviral vectors that are capable of generating broad immune responses while avoiding the problems of vector-specific immunity which has limited the development of other adenoviruses as vectors for vaccines.

"We have identified promising antigens and we have superior technology to present them," said Dr. Joseph Bruder, Director of Research and head of GenVec's malaria program. "We are pleased with the progress we are making towards the goal of creating a viable vaccine against malaria."

In October 2012, GenVec announced an agreement, valued at approximately $3.5 million, with the Naval Medical Research Center to support malaria vaccine development.  Under the terms of the agreement, GenVec is responsible for producing clinical supplies of its malaria vaccine, which utilizes its novel, proprietary technology.  The Naval Medical Research C
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SOURCE GenVec, Inc.
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