Navigation Links
Promising Data ATIR Studies Presented by NIH Investigators
Date:11/28/2007

AMSTERDAM, November 28 /PRNewswire/ -- Kiadis Pharma announced today the presentation of the results obtained so far in the physician initiated study led by Dr. Stephan Mielke* and Dr. John Barrett* of the National Heart, Lung, and Blood Institute (NHLBI) a department of the National Institutes of Health (NIH) on Kiadis' lead product ATIR at the AABB annual meeting & TXPO 2007 in Anaheim, California.

According to the NHLBI investigators the challenge in the field of allogeneic bone marrow transplantations lies with disease control, Graft versus Host Disease (GvHD) control and donor availability. Doctors Barrett and Mielke have focused on controlling GvHD whilst sparing the Graft versus Leukemia (GvL) effect and also on increasing donor availability.

The investigators have published the preclinical data showing promising results with Kiadis Pharma's ATIR in eliminating alloreactive T cells from donor grafts (Mielke et al. Blood, 2007). These results have led to the start of a phase II study with ATIR by the NHLBI. This trial is designed to demonstrate that ATIR treatment may overcome the need of immunosuppressant prophylaxis post transplantation. Prophylaxis is currently standard practice to prevent GvHD, but has a serious drawback, as it increases the chance of infection and also the relapse rate. Thus ATIR does not only intend to prevent GvHD, but could also reduce the rates of infection and relapse. Together, these complications account for approximately 70 % of allogeneic transplant related mortality.

For the complete press release go to http://www.kiadis.com/News

*Note

Dr John Barrett is Chief of the Allotransplant Section at National Heart, Lung, and Blood Institute (NHLBI) of National Institutes of Health (NIH) in Bethesda, MD, USA, where the trial is being performed. Dr Stephan Mielke, who initiated this study as principal investigator at NHLBI, is currently worki
'/>"/>

SOURCE Kiadis Pharma
Copyright©2007 PR Newswire.
All rights reserved

0

GOOD

Page: 1 2

Related biology technology :

1. Drugs from Johnson & Johnson/Basilea and Forest Are the Most Promising Antibiotics in the Community-Acquired Pneumonia Pipeline
2. Three Studies by Independent Scientists Highlighting Pressure Cycling Technology (PCT) to be Presented this Week at the British Mass Spectrometry Societys 29th Annual Meeting
3. Caliper Life Sciences Introduces High Throughput RNA Assay to Improve Workflow in Gene Expression Studies
4. Sigma-Aldrich and the Universite de Montreal Establish Collaboration for RNA Interference Studies
5. Argonne researcher studies what makes quantum dots blink
6. Three PDX (Pralatrexate) Studies Presented at the 2007 AACR-NCI-EORTC Conference
7. AIM-Quoted Verona Pharma Progresses Anti-Asthma Drug Studies
8. Rosetta Genomics Announces Initiation of In Vivo Studies Following Successful Completion of First Milestone in MicroRNA-based Therapeutic Program for Liver Cancer
9. Survival Data Presented From Phase II Study of Investigational Drug ZD4054 in Hormone-Resistant Prostate Cancer Patients
10. New Data Presented on Immunocytokine Fusion Protein Further Supports Broad Anti-Cancer Potential Of Peregrines Anti-PS Technology Platform
11. Results of Colon Cancer Study Utilizing Pressure Cycling Technology (PCT) Presented at the American College of Gastroenterology Annual Scientific Meeting
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/17/2013)... (PRWEB) May 17, 2013 Men’s skin is ... La-roche Posay ) and has been known to react ... some men may be far from puberty, other acne causing ... pores, causing breakouts, and threatening skin with unsightly acne scars. ... from Men’s Health on how to reduce and ...
(Date:5/17/2013)... (PRWEB) May 17, 2013 Rust removal is ... and non-metal home items could be damaged. To help rust ... use of its no-scrubbing rust remover it called ... able available with 10% discount. , My Cleaning Products explained ... corroding them or by staining them. The first one, ...
(Date:5/16/2013)... Athens, OH (PRWEB) May 16, 2013 ... freezer manufactured by Global Cooling, Inc., Athens, OH, USA, ... 8, 2013 by the International Society for Biological and ... Australia. The award, given to one product annually, recognizes ... energy efficient ultra-low temperature freezer. The award was ...
(Date:5/16/2013)... Zealand (PRWEB) May 16, 2013 In late ... invited to speak to doctors in China about Appearance ... and NZ, this was her first trip to lecture in ... Hart visited Guangzhou and Fuzhou, home to 12 and 7 ... China is very high at this point in time. As ...
Breaking Biology Technology:Adult Acne Treatment, Probiotic Action Shares New Insight on Why Men’s Skin Scars from Acne and How to Prevent It 2Organic-Based Rust Remover Cuts Down Price by 10%, My Cleaning Products Details Mechanics How to Get the Discount 2Stirling Ultracold Ultra-Low Freezer Wins 2013 Outstanding New Product Award at International Biorepository Conference, Sydney, Australia 2
... the Hyatt Regency Cambridge, ... Massachusetts, ... leading marketplace for expertise, and the Biotechnology Industry,Organization (BIO) announced an ... venture investment community,registered to attend the BIO National Venture Conference, with ...
... Executive Positions, WITTEN, Germany, April 8 Sangui ... its,fiscal year ended June 30, 2006, on April 3, ... with the SEC the company almost tripled its sales,of ... level. In,FY 2006, Sangui yielded sales of approximately USD ...
... DUBLIN, Calif., April 8, 2008 Microchip,Biotechnologies, Inc. ... Centre,for DNA Barcoding (CCDB), at the Biodiversity Institute ... participant to join MBI,s early,access program for the ... is the,first fully automated and integrated system for ...
Cached Biology Technology:Gerson Lehrman Group Extends Partnership With BIO to Provide Scientific Expertise for the First Annual BIO National Venture Conference 2Gerson Lehrman Group Extends Partnership With BIO to Provide Scientific Expertise for the First Annual BIO National Venture Conference 3Sangui BioTech International, Inc., Reports Sales Increase, Continued Losses 2Sangui BioTech International, Inc., Reports Sales Increase, Continued Losses 3Canadian Centre for DNA Barcoding to Participate in Microchip Biotechnologies Early Access Program for Microchip-Based DNA Sample Preparation and Cycle Sequencing 2
(Date:5/17/2013)... An international team of scientists using a ... movement inside a living frog embryo in greater detail ... to advance biological research and the search for new ... the Karlsruher Institut fr Technologie in Germany, in collaboration ... of Energy,s Argonne National Laboratory, released the most precise ...
(Date:5/16/2013)... MARC (Maximizing Access to Research Careers) Program has ... Society (ENDO) 95th Annual Meeting in San Francisco, ... meant to promote the entry of students, postdoctorates ... of the basic science community and to encourage ... 2013 Annual Meeting. , Awards are given to ...
(Date:5/16/2013)... African-American adults living closer to a fast food restaurant ... who lived further away from fast food, according to ... Center, and this association was particularly strong among those ... published online in the American Journal of Public ... to a fast food restaurant, and among lower-income African-Americans, ...
Breaking Biology News(10 mins):New X-ray method shows how frog embryos could help thwart disease 2Body mass index of low income African-Americans linked to proximity of fast food restaurants 2Body mass index of low income African-Americans linked to proximity of fast food restaurants 3
... PatientSecure(TM) on Display at Leading Healthcare Conference, ... 20 Identity,management in a busy healthcare ... especially when it must be repeated with ... Inc., a leading supplier of,innovative computer products, ...
... team of researchers led by the Smithsonian Institution has ... to as the hobbit, a 3-foot-tall, 18,000-year-old hominin skeleton, ... Flores. This study offers one of the most striking ... an island remnant of one of the oldest human ...
... Women with low levels of vitamin D have an ... by the University of Pittsburgh Graduate School of Public Health ... American Society for Bone and Mineral Research at the Hawaii ... and colleagues evaluated patient data on 400 women enrolled in ...
Cached Biology News:Fujitsu and HT Systems Partner to Provide Biometric Patient Identity Management 2Fujitsu and HT Systems Partner to Provide Biometric Patient Identity Management 3Fujitsu and HT Systems Partner to Provide Biometric Patient Identity Management 4New research sheds light on 'Hobbit' 2Low vitamin D linked to higher risk of hip fracture 2
Ready-to-use; 40mg/ml X-Gal and 32mg/ml IPTG...
This BioSolution package is excellent for doing fluorescence thermal melt experiments on nucleic acids, studies involving biomolecular interactions, protein folding experiments, and more!...
... Error-free cloning of BAC (100+kb), fosmid (40kb), ... insert stability than any othe BAC vector. ... high yields and easy recombinant DNA purification. ... transcription-free (pSMART VC) vectors for the highest ...
MOUSE ANTI RAT RT1Bu / MOUSE Ia:BIOTIN Immunogen: Rat thymocyte membrane glycoproteins...
Biology Products: