Navigation Links
Prometheus Laboratories and UCLA Sign Agreement to Validate Biological Markers of Mucosal Healing in IBD
Date:12/9/2010

SAN DIEGO, Dec. 9, 2010 /PRNewswire/ -- Prometheus Laboratories Inc., a specialty pharmaceutical and diagnostic company, and The Regents of the University of California, Los Angeles campus, today announced the execution of an exclusive research agreement that will focus on the identification of biological markers of mucosal healing in patients with Inflammatory Bowel Disease (IBD). The research will be led by Dr. Jonathan Braun, Chair of the Department of Pathology and Laboratory Medicine and a professor of molecular and medical pharmacology, UCLA David Geffen School of Medicine.

Using a cross sectional study design, Dr. Braun's laboratory will determine the correlation of genotoxicity markers to mucosal healing and disease activity in IBD patients. Prometheus will evaluate in its laboratory, additional markers of inflammation and other markers traditionally associated with the diagnosis and prognosis of IBD.

"We have come to realize that symptom response is not a true indication that a drug has been effective in stopping the progression of IBD. We need to look at mucosal healing as a more accurate predictor of effective response," said Dr. Jonathan Braun. "There is a clinical need for a non-invasive biomarker of mucosal healing as currently this has been seen using a colonoscopy."

"Adding this research project to our R&D portfolio is the latest in a series of investments Prometheus has made to answer the clinical questions related to optimization of the use of biologic therapies commonly used in IBD treatment," said Joseph M. Limber, President & Chief Executive Officer of Prometheus. "Our goal is to be able to answer the clinical questions of who will respond to these drugs up front, how one can manage patients most effectively while on these drugs and to have a non-invasive measurement of treatment efficacy."

Under the terms of the exclusive agreement, Prometheus will fund the research activities in Dr. Braun's laboratory in exchange for rights to any intellectual property generated as a result of the project. Prometheus holds a license to technology Dr. Braun co-invented and Dr. Braun is a co-founder of Prometheus. 

About Prometheus

Prometheus Laboratories Inc. is committed to improving lives through the development and commercialization of novel pharmaceutical and diagnostic products that enable physicians to provide greater individualized patient care. Prometheus is a leader in applying the principles of personalized medicine to the diagnosis and treatment of gastrointestinal diseases and is applying these principles to oncology. Its strategy includes the marketing and delivery of pharmaceutical products complemented by proprietary diagnostic testing services. By integrating therapeutics and diagnostics, Prometheus believes it can provide physicians with more targeted solutions to optimize care for their patients. Prometheus' corporate offices are located in San Diego, California.


'/>"/>
SOURCE Prometheus Laboratories Inc.
Copyright©2010 PR Newswire.
All rights reserved

Related biology technology :

1. Prometheus Research Launches Solutions Group to Springboard HTSQL-based Solutions for Customers
2. Prometheus and Tarrot Laboratories Collaborate to Identify Markers Associated With Response to Anti-TNF Therapies in Crohns Disease
3. Prometheus Research Informatics Technology Enables Multiple Presentations at IMFAR
4. Prometheus Research Awarded National Science Foundation Grant for Easy to Use, Web-Enabled Database Software
5. DNA Genotek Sample Collection Kit Selected by Prometheus for MyCeliacID™ Genetic Test
6. Prometheus Research Signs 3-Year Contract With Simons Foundation to Expand HTSQL Informatics System for Autism Research
7. Prometheus Receives New York State Approval for PROMETHEUS(R) IBS Diagnostic, First Blood Test for Irritable Bowel Syndrome
8. Prometheus Strengthens Intellectual Property Portfolio with Newly Issued Patents for Thiopurine Metabolite Testing
9. Terso Solutions RFID Jump Start Takes the Risk Out of Implementing RFID for Hospitals and Research Laboratories Looking to Streamline Operations and Improve Regulatory Compliance
10. MO BIO Laboratories, Inc. DNA Isolation Products Used to Analyze Microbes Present in Deepwater Horizon Oil Plume
11. Forensic Laboratories Develops First Oral Fluid Test for Ethyl Sulfate Detection
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/5/2016)... HILL, N.C. , Feb. 5, 2016  In ... key role for a host of launch activities including ... importance of this launch activity is especially high in ... specialists. Best Practices and the Role of ... will help companies focused on oncology therapies find better ...
(Date:2/4/2016)... ... February 04, 2016 , ... ... training, today announced an interactive FDA compliance training course, Writing ... Affairs Professional Society) accredited interactive course on Morf Playbook—now conveniently available on smartphones ...
(Date:2/4/2016)... Church, VA (PRWEB) , ... ... ... first-year cybersecurity conference presented by Bloomsburg University’s Digital Forensics Club, takes place ... PA. The two-day event features 20+ speakers and activities such as workshops ...
(Date:2/4/2016)... , February 4, 2016 ... a biotechnology acceleration company is pleased to provide the following ... --> Over the last 3 months we have ... securities purchase agreements exceeding $1,000,000. As a result, we have ... Mannin Research Inc. license agreement and expect that development to ...
Breaking Biology Technology:
(Date:2/1/2016)... MELBOURNE, Fla. , Feb. 1, 2016  Wocket® smart wallet ( ... actor and television personality, Joey Fatone . Las ... and greet fans. --> Las Vegas , ... --> The new video ad was filmed at the ... Joey appeared at the Wocket booth to meet and greet fans. ...
(Date:1/25/2016)...   Unisys Corporation (NYSE: UIS ) today announced ... International Airport, New York City , to help ... to enter the United States using passports ... pilot testing of the system at Dulles last year. The ... during January 2016. --> pilot testing of the ...
(Date:1/22/2016)... , Jan. 22, 2016 ... addition of the "Global Biometrics Market ... their offering. --> http://www.researchandmarkets.com/research/p74whf/global_biometrics ... "Global Biometrics Market in Retail Sector ... --> Research and Markets ( ...
Breaking Biology News(10 mins):