Navigation Links
Promega Now Offers Complete Solution for Profiling Kinase Inhibitor Compounds Against the Human Kinome
Date:7/7/2010

Promega announces that from a single platform, scientists can efficiently profile lead compounds in their own lab with new Kinase Enzyme Systems from Promega and SignalChem.

Madison, WI (PRWEB) July 7, 2010 -- Promega Corporation has partnered with SignalChem Pharmaceuticals to launch a flexible and complete kinase solution for the profiling of lead compounds against kinases representative of all major families of the kinome. By using this single platform, scientists can easily profile lead compounds in their own laboratories in a cost-effective manner with no loss in sensitivity.

The complete solution is accomplished by combining an expanding series of unique Kinase Enzyme Systems with Promega ADP-Glo™ Kinase Assay. The Kinase Enzyme Systems, used in concert with the new universal, bioluminescent ADP-Glo Kinase Assay from Promega, provide all of the necessary tools and give drug screeners unprecedented ease to profile inhibitors against the human kinome for off-target effects.

Each Kinase System is composed of a unique protein kinase enzyme, cognate kinase substrate and enzyme buffer. All of the Kinase Enzyme Systems have been optimized and QC’d with the ADP-Glo Assay. The ADP-Glo Kinase Assay is as sensitive as radiometric kinase assays and is quickly replacing such traditional technology.

“This partnering of SignalChem’s kinase reagents with the Promega ADP-Glo detection assay for kinases is an ideal fit. Now researchers can obtain all the necessary components to test protein kinase inhibition from a single source while still obtaining the level of sensitivity obtained with traditional radiometric assays.” said Jasbinder Sanghera, Ph.D., President & CSO of SignalChem Pharmaceuticals, of British Columbia, Canada.

Promega is the sole distributor of Kinase Enzymes Systems from SignalChem. Each Kinase Enzyme System will be available as a stand-alone enzyme system or will be sold together with ADP-Glo Assay.

Promega Corporation is a leader in providing innovative solutions and technical support to the life sciences industry. The company’s 2,000 products enable scientists worldwide to advance their knowledge in genomics, proteomics, cellular analysis, molecular diagnostics and human identification. Founded in 1978, the company is headquartered in Madison, WI, USA with branches in 14 countries and over 50 global distributors. For more information about Promega, visit www.promega.com.

# # #

Read the full story at http://www.prweb.com/releases/2010/07/prweb4229264.htm.


'/>"/>
Source: PRWeb
Copyright©2010 Vocus, Inc.
All rights reserved  

Related biology technology :

1. Promega Releases 2009 Corporate Sustainability Report
2. Promega and Cellular Dynamics Partner to Validate Stem Cell-Based In Vitro Assays for Predicting Drug-Induced Cardiotoxicity
3. New Promega Maxwell 16 LEV Blood DNA Kit Surpasses Concentration Standards in Less Time
4. NDIS Approval of Promega PowerPlex Kit Clears Path for More DNA Profiles to be Added to U.S. Database
5. Promega and SwitchGear Publish Findings from Combined Technologies that Correlate Binding Events and Transcriptional Activity
6. Promega HaloTag Protein Purification System Makes it Easier to Purify Difficult-to-Express Proteins
7. New STR Systems from Promega Comply with Latest DNA Database Standards
8. Celsis In Vitro Technologies and Promega to Offer Fast, Reliable Solutions for ADME-Tox Testing With Primary Hepatocytes
9. Research from Rensselaer Polytechnic Institute professor offers clues to Alzheimers disease
10. Carl Zeiss Offers Online Promotions – Discounts on Stereomicroscopy and Converting to 3D Imaging
11. MD Biosciences Offers Occlusion-induced Myocardial Infarct Model for Investigating the Cardio-protection of a Drug Treatment in the Event of Ischemia/reperfusion Injury
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Promega Now Offers Complete Solution for Profiling Kinase Inhibitor Compounds Against the Human Kinome  
(Date:6/24/2016)... ... June 24, 2016 , ... While the majority of commercial spectrophotometers and fluorometers ... the 6000i models are higher end machines that use the more unconventional z-dimension of ... beam from the bottom of the cuvette holder. , FireflySci has developed several ...
(Date:6/23/2016)... 2016 /PRNewswire/ - FACIT has announced the creation ... biotechnology company, Propellon Therapeutics Inc. ("Propellon" or "the ... a portfolio of first-in-class WDR5 inhibitors for the ... WDR5 represent an exciting class of therapies, possessing ... for cancer patients. Substantial advances have been achieved ...
(Date:6/23/2016)... 2016  The Biodesign Challenge (BDC), a university competition ... harness living systems and biotechnology, announced its winning teams ... New York City . The ... projects at MoMA,s Celeste Bartos Theater during the daylong ... senior curator of architecture and design, and Suzanne ...
(Date:6/23/2016)... Apellis Pharmaceuticals, Inc. today announced positive ... its complement C3 inhibitor, APL-2. The trials were ... studies designed to assess the safety, tolerability, pharmacokinetics ... healthy adult volunteers. Forty subjects were ... dose (ranging from 45 to 1,440mg) or repeated ...
Breaking Biology Technology:
(Date:3/31/2016)... R.I. , March 31, 2016  Genomics firm ... of founding CEO, Barrett Bready , M.D., who ... members of the original technical leadership team, including Chief ... President of Product Development, Steve Nurnberg and Vice President ... returned to the company. Dr. Bready served ...
(Date:3/23/2016)... March 23, 2016 ... Sicherheit Gesichts- und Stimmerkennung mit Passwörtern ... (NASDAQ: MESG ), ein führender Anbieter ... Unternehmen mit SpeechPro zusammenarbeitet, um erstmals dessen ... wird die Möglichkeit angeboten, im Rahmen mobiler ...
(Date:3/22/2016)... Ontario , PROVO and ... Newborn Screening Ontario (NSO), which operates the ... for molecular testing, and Tute Genomics and UNIConnect, ... management technology respectively, today announced the launch of a ... next-generation sequencing (NGS) testing panel. NSO ...
Breaking Biology News(10 mins):