Navigation Links
Programmed nanoparticles organize themselves into highly complex nanostructures
Date:11/7/2013

le to guide the triblock macromolecules into soft nanoparticles with a diameter of roughly 50 nanometers. The choice of solvents played a key role in this macromolecular self-assembly process. The solvents were precisely selected and used so that the varying solubility of the three blocks and the incompatibility of the polymers with one another contributed significantly to the quality of the desired interior structure of the nanoparticles.

The scientists applied this technique to two types of triblock terpolymers. These differed with regard to the chemical properties of the middle blocks. The block sequences of the macromolecules were A-B-C and A-D-C, respectively. The first results in nanoparticles with a single bonding site and tends to form spherical clusters, while the latter creates nanoparticles with two bonding sites and thus tends to form linear superstructures. Importantly, in both cases the structure of the nanoparticles is preprogrammed by the chemical structure of the source macromolecule in the same way as the structure of a protein is determined by its amino acid sequence.

However, the process of self-assembly does not end with the nanoparticles. If the nanoparticles formed by each type of macromolecule were left to their own, spherical superstructures would result on the one hand and linear superstructures on the other. Mller's team has developed and implemented a different approach. The nanoparticles with one and two bonding sites are mixed so that they aggregate together into a completely new superstructure in a process of co-assembly. In the final superstructure, the nanoparticles originating from the A-B-C molecules and nanoparticles formed by the A-D-C molecules alternate in a precisely defined pattern.

When viewed under a transmission electron microscope, the new superstructure bears a strong resemblance to a caterpillar larva, because it also consists of a series of clearly separate, regularly ordered sections. Mll
'/>"/>

Contact: Dr. Axel H. E. Müller
axel.mueller@uni-mainz.de
49-613-139-22372
Johannes Gutenberg Universitaet Mainz
Source:Eurekalert  

Page: 1 2 3 4

Related biology technology :

1. Preliminary Research, Led By Dr. Vincent Giampapa, Finds Aged Adult Stem Cells Can Be Functionally Reprogrammed To Act Like Younger Cells
2. Marshall study shows nanoparticles used as additives in diesel fuels can travel from lungs to liver
3. Metal nanoparticles shine with customizable color
4. New measuring techniques can improve efficiency, safety of nanoparticles
5. Light touch keeps a grip on delicate nanoparticles
6. Nanoparticles seen as artificial atoms
7. Nanoparticles found in moon glass bubbles explain weird lunar soil behavior
8. Study improves understanding of surface molecules in controlling size of gold nanoparticles
9. Gold nanoparticles could treat prostate cancer with fewer side effects than chemotherapy
10. New structural information on functionalization of gold nanoparticles
11. New imaging technique homes in on electrocatalysis of nanoparticles
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Programmed nanoparticles organize themselves into highly complex nanostructures
(Date:1/22/2015)... , Jan. 22, 2015   Cypher Genomics, ... Sequenom, Inc. (NASDAQ: SQNM ), the ... agreement for next generation noninvasive prenatal tests (NIPT). ... interpretation technology, called Mantis™, to advance analysis of ...
(Date:12/24/2014)... Dec. 24, 2014  United Therapeutics Corporation (NASDAQ: ... MDT ) has submitted a pre-market approval application ... the use of Medtronic,s SynchroMed ® II implantable ... use with United Therapeutics, Remodulin ® (treprostinil) Injection ...
(Date:12/24/2014)... St. Louis, Missouri (PRWEB) December 23, 2014 ... Swiss biotechnology company, Syngenta, are in the process of being ... consolidated case is In Re: Syngenta AG MIR 162 Corn ... the District of Kansas. , Management of the Syngenta GMO ...
(Date:12/24/2014)... December 23, 2014 The report ... its definition, classification, application and industry overview. This ... product cost structure. Production is separated by regions, ... raw materials, equipment, downstream client survey, marketing channels, ...
Breaking Biology Technology:Cypher Genomics and Sequenom Announce Development Agreement 2Cypher Genomics and Sequenom Announce Development Agreement 3Cypher Genomics and Sequenom Announce Development Agreement 4United Therapeutics Announces Submission Of Pre-Market Approval Application For Implantable Drug Infusion System To Deliver Remodulin 2United Therapeutics Announces Submission Of Pre-Market Approval Application For Implantable Drug Infusion System To Deliver Remodulin 3United Therapeutics Announces Submission Of Pre-Market Approval Application For Implantable Drug Infusion System To Deliver Remodulin 4Carey Danis & Lowe Reports on Syngenta GMO Corn Transfer Order 2Worldwide Methyl Mercaptan Market 2015-2020 Forecasts on Development & Trends Now Available at ReportsnReports.com 2
... Groton , Connecticut MORRISVILLE, N.C., May ... of APIs, intermediates and Drug Products to the pharmaceutical industry, ... announce the recent award by Pfizer Inc. as the 2008 ... Groton, Connecticut R&D center on May 1, 2009. The award ...
... Blinatumomab in NHL and ALL Highlighted at the ... Combination Data in Breast Cancer to Be Presented ... MeetingBETHESDA, Md., May 20 Micromet, Inc. (Nasdaq: ... novel, proprietary antibodies for the treatment of cancer, ...
... WOODMERE, N.Y., May 19 In an eleventh-hour attempt ... QGLY ) has issued a press release claiming that ... a key staff member of a subsidiary of Quigley, and ... who have offered their own slate of Quigley,s Board of ...
Cached Biology Technology:Pfizer Global R&D Presents 2008 Top Intermediates CMO Award to Asymchem 2Micromet to Present New Clinical Data on Blinatumomab at EHA and on Adecatumumab at ASCO 2Micromet to Present New Clinical Data on Blinatumomab at EHA and on Adecatumumab at ASCO 3Micromet to Present New Clinical Data on Blinatumomab at EHA and on Adecatumumab at ASCO 4Micromet to Present New Clinical Data on Blinatumomab at EHA and on Adecatumumab at ASCO 5In Eleventh-Hour Smear Attempt, Quigley Management Sacrifices Key Employee of its Pharma Division 2In Eleventh-Hour Smear Attempt, Quigley Management Sacrifices Key Employee of its Pharma Division 3
(Date:1/22/2015)... Jan. 13, 2015  Today, FreeWavz ( www.FreeWavz.com ), ... crowdfunding campaign on Fundable, https://www.fundable.com/freewavz . FreeWavz ... production capacity to meet customer demand. ... http://photos.prnewswire.com/prnh/20150113/168790 Invented by ...
(Date:1/22/2015)... 16, 2015  A man-made form of insulin delivered by ... capabilities in adults with mild cognitive impairment and Alzheimer,s ... researchers at Wake Forest Baptist Medical Center. ... mild cognitive impairment (MCI) or mild to moderate Alzheimer,s ...
(Date:1/22/2015)... , Jan. 21, 2015  Analyst Report Issued by Small ... Brands report showed that planet-wide, transactions at merchants on the ... the total number of credit, debit, and prepaid cards reached ... were victims of fraudulent card usage in 2012, and credit ...
Breaking Biology News(10 mins):FreeWavz Launches on Fundable to Drive Speed-to-Market in 2015 2Nasal Spray with Insulin Equivalent Shows Promise as Treatment for Adults with Mild Cognitive Impairment, Alzheimer's Dementia 2Nasal Spray with Insulin Equivalent Shows Promise as Treatment for Adults with Mild Cognitive Impairment, Alzheimer's Dementia 3$4.80 Near Term Price Target with "Buy" given by CapRock Research for NXT-ID, Inc. (NASDAQ: NXTD) issued by Small Cap IR 2
... Epitomics, Inc. announced today that it has signed a ... HealthCare). Epitomics will use its proprietary rabbit monoclonal antibody ... identification and validation. "Epitomics has had ... is a major expansion of our collaboration and confirms ...
... German . Medicines from plants ... that has nothing in common with what the researchers ... Ecology IME in Aachen, Germany, are doing. They use ... many other medications, cannot be chemically produced. Biologically ...
... persist in the often violently competitive realm of bacteria, ... University Bloomington biologists have learned that in one bacterium, ... cheaters and arrest their bids for dominance. ... suppress social cheaters," said Gregory Velicer, who with Ph.D. ...
Cached Biology News:Medicines from plants 2'Policing' stops cheaters from dominating groups of cooperative bacteria 2'Policing' stops cheaters from dominating groups of cooperative bacteria 3'Policing' stops cheaters from dominating groups of cooperative bacteria 4
Rabbit Anti-melatonin (different linkage) Polyclonal Antibody...
Transcription factor Sp2. [Source:Uniprot/SWISSPROT;Acc:Q02086] Antigen: Recombinant Protein Epitope Signature Tag (PrEST)....
Proline-serine-threonine phosphatase-interacting protein 2...
Rabbit Anti-melatonin (different linkage) Polyclonal Antibody...
Biology Products: