Navigation Links
Pro Bono Bio Announces the Successful Development of Subcutaneous and Long-Acting Blood Factors VIIa,VIII and IX for the Treatment of Haemophilia
Date:9/10/2012

LONDON and MOSCOW, September 11, 2012 /PRNewswire/ --

Subcutaneous blood factors expected to revolutionise the treatment paradigm of haemophiliac patients worldwide

Pro Bono Bio Group plc ("PBB"), the international healthcare group, announces the successful conclusion of a series of pre-clinical trials in haemophiliac subjects conducted with the world's first long acting blood Factors VIIa, VIII and IX capable of subcutaneous administration. The results of these trials are of great importance as these novel long-acting, subcutaneous blood factors are expected to revolutionise the treatment paradigm for haemophilia sufferers worldwide. The availability of PBB's subcutaneous blood factors would make self-administration by patients at home much easier leading to a significant improvement in treatment compliance and reduction in healthcare system costs by avoiding the need for regular IV infusions.

Key findings from the 8 trials with 6 products conducted at the University of Alabama were:

  • PBB's current subcutaneous form of FVIIa achieved up to 3 days of haemostatic cover providing the prospect of sustained prophylactic treatment for haemophilia A patients who suffer an immune response to FVIII meaning that FVIII is no longer a viable therapy for them.
  • PBB's current intravenous form of Factor VIIa achieved a 12x extension of haemostasis over current commercially available products. This means it could offer significant advantages in trauma applications in hospitals where haemostatic cover can be maintained for the duration of long operations and post-operation, without the current need for multiple administrations and related complications.
  • PBB's subcutaneous form of Factor VIII for haemophilia A achieved a circulating dose level of 20% of the intravenous version and also maintained haemostasis for 72 hours, meaning that it is already suitable for twice-weekly dosing a
    '/>"/>

SOURCE Pro Bono Bio
Copyright©2012 PR Newswire.
All rights reserved

0

GOOD

Page: 1 2 3 4 5 6

Related biology technology :

1. Keryx Biopharmaceuticals, Inc. Announces Upcoming Poster Presentations of Zerenex™ (Ferric Citrate) at the Upcoming American Society of Nephrology Kidney Week 2011 Annual Meeting
2. VaxyGen Assay Services, LLC Announces Launch of Custom Bioassay Services and Operations
3. Sequenom Announces Participation at the Lazard Capital Markets 8th Annual Healthcare Conference
4. ACORN Research, LLC Announces Partnership with AdeptBio, LLC
5. GeoVax Labs, Inc. Announces Nine Month 2011 Financial Results
6. WuXi PharmaTech Announces Third-Quarter 2011 Results
7. Chimerix Announces Late-Breaking Poster Presentation at Kidney Week 2011 Annual Meeting
8. Spherix Announces Third Quarter Financial Results
9. Modern Mobility Aids, Inc. Announces November 30, 2011 Closing of Lumigene Acquisition
10. MedImmune Announces Winners of Its 6th Annual Global Abstract Competition
11. Nile Therapeutics Announces Top-Line Results in Clinical Trial Evaluating the Subcutaneous Infusion of Cenderitide, Meets Primary Endpoint
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/20/2013)... , May 20, 2013  Dr. ... of nucleic acid research, recently launched a new blog ... with Zon ( zon.trilinkbiotech.com ), focuses on what,s trending ... interviews with industry thought leaders, discussions of research presented ... more. Dr. Zon (PhD Princeton University ...
(Date:5/20/2013)... , Md. and BALTIMORE , May ... (BHI), a regional private-public partnership focusing on commercializing ... funding in Central Maryland , ... M.B.A., as the first Entrepreneur-in-Residence (EIR) for BHI ... National Heart, Lung and Blood Institute (NHLBI). ...
(Date:5/20/2013)... Rhythm announced today the results of a ... novel ghrelin agonist for the treatment of diabetic gastroparesis ... RM-131 significantly accelerates early gastric emptying and reduces upper ... diabetic gastroparesis. The findings were presented at the Digestive ... and recently published in Clinical Gastroenterology and ...
(Date:5/20/2013)... Recognizing exciting and innovative scientific ... its 2013 Class of Young Professors. Over ... this outstanding international group with more than $824,000 ... to meet global challenges.     , The DuPont Young ... and untenured research faculty working in areas of ...
Breaking Biology Technology:Dr. Gerald 'Jerry' Zon Launches New Blog for TriLink BioTechnologies 2BioHealth Innovation, Inc. Names Ram Aiyar as Entrepreneur-in-Residence to NIH National Heart, Lung and Blood Institute 2BioHealth Innovation, Inc. Names Ram Aiyar as Entrepreneur-in-Residence to NIH National Heart, Lung and Blood Institute 3BioHealth Innovation, Inc. Names Ram Aiyar as Entrepreneur-in-Residence to NIH National Heart, Lung and Blood Institute 4Rhythm Announces Phase 1b Results for Ghrelin Prokinetic RM-131 for Gastroparesis in Patients with Type 1 Diabetes 2Rhythm Announces Phase 1b Results for Ghrelin Prokinetic RM-131 for Gastroparesis in Patients with Type 1 Diabetes 3DuPont Celebrates Scientific Innovation by Recognizing Young Professors 2DuPont Celebrates Scientific Innovation by Recognizing Young Professors 3
... Chembio Diagnostics, Inc. (OTC.PK: CEMI and OTC.QB: ... diagnostic tests, today announced that Lawrence A. Siebert, President ... Showcase in San Francisco at approximately 5:30 pm Eastern ... 2012.   The conference will be simultaneously ...
... 9, 2012 /PRNewswire-Asia-FirstCall/ -- 3SBio Inc. (NASDAQ: ... biotechnology company focused on researching, developing, manufacturing and marketing ... financial officer will attend the UBS Greater China Conference ... of Mr. Tan,s presentation will be archived at ...
... Mass., Jan. 9, 2012  Idenix Pharmaceuticals, Inc. (NASDAQ: ... discovery and development of drugs for the treatment of ... 12-week phase IIb clinical trial of IDX184, the Company,s ... virus (HCV) infection.  IDX184, a pan-genotypic oral nucleotide polymerase ...
Cached Biology Technology:Chembio Presenting at Biotech Conference 2Chembio Presenting at Biotech Conference 3Idenix Reports Positive Interim Data for HCV Nucleotide Inhibitor, IDX184 2Idenix Reports Positive Interim Data for HCV Nucleotide Inhibitor, IDX184 3Idenix Reports Positive Interim Data for HCV Nucleotide Inhibitor, IDX184 4Idenix Reports Positive Interim Data for HCV Nucleotide Inhibitor, IDX184 5
(Date:5/20/2013)... research suggests that a compound abundant in the Mediterranean ... , By altering a very specific step in ... normal cells that die as scheduled. , One way ... that would cause them to die on a regular ... in cells, led by Ohio State University researchers, found ...
(Date:5/20/2013)... A novel vaccine study from South Dakota State ... be unveiled at the American Association of Pharmaceutical Scientists, ... Monday, May 20 - Wednesday, May 22 at the ... main goal of a vaccine is to stimulate the ... the disease", explained Dr. Hemachand Tummala, assistant professor of ...
(Date:5/20/2013)... Colo., USA New Geology articles ... May 2013 cover a wide swath of geoscience ... oceanography, geophysics, and paleobotany. Locations studied include Siberia; ... at Alpi Apuane, Italy; Ukraine; Mars; and the ... , 1. Rubies, jadeite, and plate tectonics;, 2. ...
Breaking Biology News(10 mins):The compound in the Mediterranean diet that makes cancer cells 'mortal' 2The compound in the Mediterranean diet that makes cancer cells 'mortal' 3Germ-fighting vaccine system makes great strides in delivery 2New in GEOLOGY: Gems, Darwin, Mars, Hemp, Snowball Earth, a Siberian Impact Crater, and More 2New in GEOLOGY: Gems, Darwin, Mars, Hemp, Snowball Earth, a Siberian Impact Crater, and More 3New in GEOLOGY: Gems, Darwin, Mars, Hemp, Snowball Earth, a Siberian Impact Crater, and More 4New in GEOLOGY: Gems, Darwin, Mars, Hemp, Snowball Earth, a Siberian Impact Crater, and More 5New in GEOLOGY: Gems, Darwin, Mars, Hemp, Snowball Earth, a Siberian Impact Crater, and More 6New in GEOLOGY: Gems, Darwin, Mars, Hemp, Snowball Earth, a Siberian Impact Crater, and More 7New in GEOLOGY: Gems, Darwin, Mars, Hemp, Snowball Earth, a Siberian Impact Crater, and More 8New in GEOLOGY: Gems, Darwin, Mars, Hemp, Snowball Earth, a Siberian Impact Crater, and More 9New in GEOLOGY: Gems, Darwin, Mars, Hemp, Snowball Earth, a Siberian Impact Crater, and More 10New in GEOLOGY: Gems, Darwin, Mars, Hemp, Snowball Earth, a Siberian Impact Crater, and More 11
... Dec. 7, 2009, New York, N.Y./Los Angeles, Calif.: ... is awarding $9.68 million to support high-risk/high-reward cancer research ... each investigator will receive a total of up to ... which supports the next generation of cancer research leaders. ...
... battle zone. Cells constantly compete with one another for space and ... is well known to be the survival of the fittest, how ... as clear. A study on fruit flies published in the October ... how stem cells win this battle by literally sticking around. ...
... the Natural History Museum believe that carnivorous behaviour in plants ... grown plants such as petunias at least part ... Victorian Gothic, Darwin and modern insights into vegetable carnivory, is ... of the Linnean Society . Carnivorous plants have caught ...
Cached Biology News:Stand Up to Cancer funds high-risk/high-reward cancer research by 13 young scientists 2Stand Up to Cancer funds high-risk/high-reward cancer research by 13 young scientists 3Stand Up to Cancer funds high-risk/high-reward cancer research by 13 young scientists 4Stand Up to Cancer funds high-risk/high-reward cancer research by 13 young scientists 5Stand Up to Cancer funds high-risk/high-reward cancer research by 13 young scientists 6Stem cells battle for space 2Scientists think 'killer petunias' should join the ranks of carnivorous plants 2
... an endoribonuclease, the RNA strand of ... origin, e.g. that of phage FX174, ... x poly(dT). RNase H produces ribonucleotides ... no activity is detected with polyribonucleotides ...
... Source: E. coli strain containing an overproducing clone ... catalyzes the formation of a phosphodiester bond between ... duplex DNA or RNA. It repairs single-stranded nicks ... will join both blunt-end and cohesive-end fragments of ...
Goat polyclonal to Haptoglobin ( Abpromise for all tested applications). Antigen: Affinity purified human haptoglobin. Entrez GeneID: 3240 Swiss Protein ID: P00738...
SHEEP ANTI BOVINE BETA-LACTOGLOBULIN A...
Biology Products: