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Presentation of Phase IIa Results for Cytos Biotechnology's Hypertension Vaccine at the American Heart Association Scientific Sessions 2007
Date:11/6/2007

tihypertensive drugs: a class of drugs used for treatment of high blood pressure.

Cardiovascular events: refer to conditions affecting the cardiovascular system, which comprises the heart, the blood vessels, and the cells and plasma that make up the blood.

Circadian: a circadian rhythm is a roughly 24-hour cycle in the physiological processes of living beings.

Compliance: a patient's adherence to a recommended course of treatment.

Diastolic blood pressure (DBP): the lowest pressure within the arterial blood stream occurring during each heart beat.

Double-blind: a set-up often applied in clinical trials where neither the doctor nor the patient knows if placebo or the active drug substance is applied.

Half-life: time required in which half the amount of a biological substance (e.g. antibodies) is removed from the organism.

mmHg: blood pressure values are universally stated in millimetres of mercury (mmHg).

Myocardial infarction: commonly known as a heart attack; is a disease state that occurs when the blood supply to a part of the heart is interrupted.

Peptide: a fragment of a protein comprised of two or more amino acids.

Phase IIa: clinical trial that examines a new drug candidate's safety and exploratory efficacy and may involve between 10 and 100 patients.

Placebo: dummy medical treatment.

Renin-angiotensin system (RAS): hormone system that regulates long-term blood pressure and blood volume in the body.

Receptor: a protein molecule that binds and responds to a certain interaction partner such as hormones, immune mediators or other substances.

Small molecule drugs: low molecular weight chemical compounds. Many pharmaceutical drugs are small molecules.

Stroke: a sudden interruption in the blood supply of the brain.

Systolic blood pressure (SBP): the highest pressure within the arterial blood stream occurring during each heart beat.

Therapeutic vaccine: a preparation
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SOURCE Cytos Biotechnology AG
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