Date:11/6/2007

Biotechnology AG is a public Swiss biotechnology company that specializes in the discovery, development and commercialization of a new class of biopharmaceutical products - the Immunodrugs(TM). Immunodrugs(TM) are intended for use in the treatment and prevention of common chronic diseases, which afflict millions of people worldwide. Immunodrugs(TM) are designed to instruct the patient's immune system to produce desired therapeutic antibody or T cell responses that modulate chronic disease processes. Taking advantage of the high flexibility of its Immunodrug(TM) platform, Cytos Biotechnology has built a pipeline of different Immunodrug(TM) candidates in various disease areas, of which 6 are currently in clinical development. The Immunodrug(TM) candidates are developed both in-house and together with Novartis and Pfizer Animal Health. Founded in 1995 as a spin-off from the Swiss Federal Institute of Technology (ETH) in Zurich, the company is located in Schlieren (Zurich). Currently, the company has 130 employees. Cytos Biotechnology AG has been listed on the SWX Swiss Exchange (SWX:CYTN) since October 2002.

References

1. Journal of Hypertension, 2007, 25:63.

2. World Health Organization, Atlas of Heart Disease and Stroke, 2004.

3. Hypertension 2003; 42:1206.

4. New England Journal of Medicine, 1985, 313:1315.

5. Hypertension, 2006, 47:149.

6. Hypertension Research, 2006, 29:581.

7. American Journal of Hypertension, 2004, 17:347.

8. Hypertension, 2003, 42:1137.

Glossary

Ambulatory blood pressure: blood pressure measured continuously during a normally active day; takes numerous automatic readings over a 24-hour period or longer and applies non-invasive ambulatory blood pressure monitoring devices.

Angiotensin II: a molecule of the RAS inducing vasoconstriction of blood vessels and other effects to raise blood pressure.

Antibody: class of blood proteins generated by the immune system.

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