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Predicting the fate of stem cells
Date:10/22/2013

ave different research protocols for different cell types. But as it turns out, very often those protocols don't work across many different cell lines," Nazareth said.

The work also provides a way to study differences across cell lines that can be used to predict certain genetic information, such as abnormal chromosomes. What's more, these predictions can be done in a fraction of the time compared to other existing techniques, and for a substantially lower cost compared to other testing and screening methods.

"We anticipate this technology will underpin new strategies to identify cell fate control molecules, or even drugs, for a number of different stem cell types," Zandstra said.

As a drug screening technology "it's a dramatic improvement over its predecessors," said Nazareth. He notes that in some cases, the new technology can drop testing time from up to a month to a mere two days.

Professor Peter Zandstra was awarded the 2013 Till & McCulloch Award in recognition of this contribution to global stem cell research.


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Contact: Erin Vollick
Comm.ibbme@utoronto.ca
416-946-8019
University of Toronto
Source:Eurekalert

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