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Precision Therapeutics' ChemoFx® Demonstrates Significant Role in Selection of Chemotherapy Doublets in Non Small Cell Lung Cancer

PITTSBURGH, April 12, 2011 /PRNewswire/ -- Drs. Rodney Landreneau and Matthew Schuchert from the University of Pittsburgh presented a new non small cell lung cancer study at the 2011 Society of Surgical Oncology (SSO) conference in San Antonio, Texas.  Dr. Landreneau is Director of the Lung Center at UPMC Shady Side Hospital as well as the Head of Thoracic Surgery at UPMC Passavant Medical Center and Director of the Division of Cardiothoracic Surgery at UPMC St. Margaret Medical Center.  Dr. Matthew J. Schuchert is an Assistant Professor of Surgery in the Department of Cardiothoracic Surgery at the University of Pittsburgh Cancer Institute.  

The study, titled,  "Assessment of In Vitro Chemoresponsiveness to Platinum Based Chemotherapy Doublets Lead to Improvements in 'Individualized' Therapy for Resected Non Small Cell Lung Cancer (NSCLC),"  demonstrates that while 35% of patient specimens evaluated in vitro are resistant to all three standard platinum doublets tested, 28% demonstrate a uniquely variable response, suggesting therefore that ChemoFx® chemoresponse testing may help guide optimal selection of the platinum doublet for treatment, a factor that may be crucial to the patient's outcome.

Christine Gan, Ph.D., a medical science liaison for Precision Therapeutics, noted, "Selecting the optimal platinum doublet for individual NSCLC patients is not straightforward when three equally efficacious options exist.  ChemoFx®, when used as a tool in conjunction with a physician's clinical judgment, can potentially help guide the selection of therapy in this difficult to treat disease."

According to recent statistics, lung cancer is currently responsible for 29% of cancer deaths in the United States, which represents more deaths than breast cancer, colon cancer, and prostate cancer combined. Lung cancer remains the leading cause of cancer deaths for both men and women.

About Precision Therapeutics

Precision Therapeutics, a life-science company based in Pittsburgh, Pennsylvania, is committed to improving outcomes of cancer patients.  As leaders in the science of individualizing cancer therapy through the use of a proprietary and unique live-tissue platform, Precision develops novel markers to help guide treatment decisions based on the biological processes of each individual's cancer.  

Precision's state of the art bioinformatics combined with the analysis of the live molecular, proteomic and genomic activity of each patient's cancer offer an innovative foundation for further development and commercialization of novel predictive markers for cancer therapy. 

ChemoFx® is a proprietary drug response marker which measures an individual's malignant tumor response to a range of standard therapeutic alternatives under consideration by a physician.  Precision currently receives ChemoFx® specimens from 271 top medical institutions including 20 of the 21 National Comprehensive Cancer Network (NCCN) Member Institutions, and 8 of the US News and World Report Top 10 Hospitals for Cancer Care. To date, ChemoFx® Final Reports have been provided for over 56,000 patient specimens, using 105 unique chemotherapy treatments and combinations. For more information, visit or

SOURCE Precision Therapeutics
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