Navigation Links
Precision Antibody Wins Contract to Develop 'Gold Standard' Antibodies as Part of National Cancer Institute's Clinical Proteomics Technologies for Cancer (CPTC) Initiative
Date:10/27/2009

COLUMBIA, Md., Oct. 27 /PRNewswire/ -- Precision Antibody(TM) has been selected as the antibody developer for a component of the National Cancer Institute (NCI)'s Clinical Proteomic Technologies for Cancer (CPTC), which is focused on improving the number and standardizing the quality of monoclonal antibody reagents available for clinical cancer proteomics research. The contract award is the result of a third solicitation for contract proposals from custom antibody suppliers as part of the Clinical Proteomic Reagents Resources component of the CPTC, whose mission is to develop high-quality, standardized, renewable reagents that are needed for effective proteomic analysis.

The contract is awarded to private companies through a competitive bidding process managed by Science Applications International Corporation-Frederick (SAIC-F), a wholly owned subsidiary of SAIC that operates the National Cancer Institute's leading center for cancer and AIDS research in Frederick, Maryland.

NCI's CPTC is a five-year, $104 million initiative to develop new proteomics tools and technologies that will accelerate discovery and clinical research in cancer. The antibody initiative of the CPTC's Clinical Proteomic Reagents Resource project was launched in late 2007 to address a major obstacle hindering the progress of proteomics research: The relatively small number of antibodies generated against proteins of interest, and their generally variable quality. The goal of the antibody initiative is to develop a standardized resource of very high-quality reference antibodies generated against cancer-related proteins of interest that will be made available to proteomics researchers, along with characterization data and other information intended to support replication and standardization.

"We are very pleased that SAIC-Frederick has selected Precision Antibody to contribute to this important initiative," said Jun Hayashi, Ph.D., Vice President of Precision Antibody. "Our goal is to rapidly develop and optimize antibodies for the target cancer-related antigens we have been assigned, which will help accelerate the NCI's creation of a public resource of gold-standard antibodies to advance proteomics research."

The terms of the contract call for Precision Antibody to apply its proprietary rapid antibody-generation technology to develop three monoclonal antibodies against each of 20 cancer-related target antigens produced by Argonne National Laboratory that have been identified to be of high interest to the cancer proteomics community. Other terms were not disclosed.

Following screening and initial characterization by Precision Antibody, SAIC-F will undertake screening and additional characterization of the antibodies. Techniques used in the rigorous characterization process may include ELISA and indirect ELISA, Western blot, antibody isotype, SDS-PAGE, surface plasma resonance, immunohistochemistry, immunoprecipitation, immunofluorescence, and immuno-mass spectrometry. Final characterization will be completed by the Biodesign Institute at Arizona State University and by the Royal Institute of Technology in Stockholm, Sweden, which runs the Human Protein Atlas, a comprehensive database that provides protein expression profiles for a large number of human proteins.

Once characterized and produced, NCI's final renewable, highly characterized, high-affinity antibodies and their producing hybridoma cells will be made commercially available to the research community through the Developmental Studies Hybridoma Bank at the University of Iowa. To ensure that experiments can be both repeated and compared among researchers, detailed standard operating procedures will also be provided, along with characterization data that will be available to the scientific community via a web portal (http://antibodies.cancer.gov)

About the Contract

This project is 100% supported with federal funds provided by the National Cancer Institute, National Institutes of Health, under Contract No. HHSN261200800001E. The content of this press release does not necessarily reflect the views or policies of the U.S. Department of Health and Human Services, nor does mention of trade names, commercial products, or organizations imply endorsement by the U.S. government.

About Precision Antibody (www.precisionantibody.com)

Precision Antibody(TM) provides customized, high-affinity monoclonal and polyclonal antibodies to pharmaceutical and biotechnology companies as well as to academic, government, and nonprofit research institutes for use in discovery, research, and testing of novel pharmaceuticals, biomarkers, and diagnostic tests. The company's products and services are based on a proprietary antibody discovery and development platform technology that enables rapid development and production of monoclonal antibodies from pilot to large scale. The company's comprehensive monoclonal antibody service offerings include antibody characterization, Biacore analysis, mammalian cell banking, and commercial-scale manufacturing consultation. Precision Antibody is a wholly owned service division of A&G Pharmaceutical, Inc. (www.agpharma.com) and is based in Columbia, MD.

    Contact:
    Michael Keefe
    (410) 884-4100 x11
    mkeefe@precisionantibody.com

SOURCE Precision Antibody


'/>"/>
SOURCE Precision Antibody
Copyright©2009 PR Newswire.
All rights reserved

Related biology technology :

1. Varian Medical Systems Exhibits Latest Technologies and Products Designed to Improve Speed and Precision of Radiotherapy at ESTRO 2007
2. DuPont and Precision BioSciences Collaborate to Accelerate Crop Product Development
3. Time Domain Showcases Precision Location Capability of Ultra Wideband PLUS Product Line at HIMSS 2008
4. Cellectis Sues Precision BioSciences for Infringement of its Patents Concerning Meganuclease Technology
5. SACHEM Launches 2-D HPLC e-Learning Program : New e-Learning Program Teaches Scientists How to Better Analyze and Prove Product Purity Through Greater Sensitivity and Precision in Identification of Trace Components
6. Applied Precision Introduces New Super-Resolution Imaging System Doubling Resolution of Traditional Microscopes
7. Sangamo BioSciences Announces Publication in Nature of the Use of Zinc Finger Nucleases to Accelerate Precision Trait Stacking in Commercial Crop Species
8. AMDL, Inc. Signs First Customer Agreement With Precision Diagnostic Laboratory for DR-70 (FDP) Cancer Test
9. Frost & Sullivan Awards Precision Biosciences for Technology Innovation and Molecular Design Process in the Genomics Market
10. NISTs LIDAR may offer peerless precision in remote measurements
11. Precision Stability Storage Announces Upcoming Expansion
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/27/2016)... ... 2016 , ... Cancer experts from Austria, Hungary, Switzerland, and ... new and helpful biomarker for malignant pleural mesothelioma. Surviving Mesothelioma has just published ... , Biomarkers are components in the blood, tissue or body fluids that ...
(Date:6/27/2016)... ... 2016 , ... Newly created 4Sight Medical Solutions ... healthcare market. The company's primary focus is on new product introductions, to include ... are necessary to help companies efficiently bring their products to market. , The ...
(Date:6/27/2016)... 2016  Liquid Biotech USA ... a Sponsored Research Agreement with The University of ... from cancer patients.  The funding will be used ... with clinical outcomes in cancer patients undergoing a ... be employed to support the design of a ...
(Date:6/24/2016)...  Regular discussions on a range of subjects including policies, ... entities said Poloz. Speaking at a lecture to ... he pointed to the country,s inflation target, which is set ... "In certain areas there needs ... economic goals, why not sit down and address strategy together?" ...
Breaking Biology Technology:
(Date:6/9/2016)... TURKU, Finland , June 9, 2016 ... French National Police deploy Teleste,s video security solution to ensure ... France during the major tournament ... and data communications systems and services, announced today that its ... Police Prefecture to back up public safety across ...
(Date:6/2/2016)... Perimeter Surveillance & Detection Systems, ... Infrastructure, Support & Other Service  The latest ... comprehensive analysis of the global Border Security market ... of $17.98 billion in 2016. Now: In ... in software and hardware technologies for advanced video surveillance. ...
(Date:5/12/2016)... -- WearablesResearch.com , a brand of Troubadour Research ... the Q1 wave of its quarterly wearables survey. A ... to a program where they would receive discounts for ... "We were surprised to see that so ... , CEO of Troubadour Research, "primarily because there are ...
Breaking Biology News(10 mins):