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Pradaxa® (dabigatran etexilate mesylate) Capsules Now on Formulary at Nation's Top Heart Hospitals
Date:7/21/2011

nce programs to help provide coverage for the costs of their medications.

Findings from the pivotal, Phase III RE-LY® trial showed that PRADAXA 150mg taken twice daily significantly reduced stroke and systemic embolism by 35 percent beyond the reduction achieved with warfarin in patients with NVAF.(1) Effects of PRADAXA were more apparent in patients with lower levels of INR (international normalized ratio) control.(1) Dabigatran was recently recommended in an update to atrial fibrillation treatment guidelines. PRADAXA is approved to reduce the risk of stroke and systemic embolism in patients with non-valvular atrial fibrillation in Canada, Japan, New Zealand and several other countries across four continents.  

About Atrial Fibrillation and Stroke

Atrial fibrillation can cause blood clots to form in the heart that can travel to the brain and cause a stroke.(2) Atrial fibrillation is associated with up to 15 percent of all strokes in the U.S.(3) An estimated 2.3 million Americans are living with AFib,(4) and the prevalence is expected to increase to 5.6 million by 2050.(4)  A large managed care database study showed that NVAF represents roughly 95 percent of all AFib cases in the U.S.(4)  Non-valvular atrial fibrillation refers to patients that do not have a prosthetic heart valve requiring anticoagulation, or patients with valvular disease that does not require surgical repair. Atrial fibrillation imposes a substantial economic burden to the healthcare system,(6) specifically the high costs associated with stroke.(8)

About Pradaxa® (dabigatran etexilate) Capsules

Indications and Usage

PRADAXA is indicated to reduce the risk of stroke and systemic embolism in patients with non-valvular atrial fibrillation.

IMPORTANT SAFETY INFORMATION ABOUT PRADAXA

CONTRAINDICATIONS

PRADAXA is contraindicated in patients with active patho
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SOURCE Boehringer Ingelheim Pharmaceuticals, Inc.
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