Navigation Links
'Possible Key to Alzheimer Medication'
Date:10/26/2010

'Possible Key to Alzheimer Medication' -- LEIDEN, Netherlands, October 26, 2010 /PRNewswire/ --


Advanced Search Search

  
Close
  1. Send a release
  2. Member sign in
  3. Become a member
  4. For journalists
  5. Global sites
PR Newswire: news distribution, targeting and monitoring
  1. Products & Services
  2. Knowledge Center
  3. Browse News Releases
  4. Contact PR Newswire
Biotechnology, Health Care & Hospitals, Medical Pharmaceuticals, Clinical Trials & Medical Discoveries Click to view news release full screen  

'Possible Key to Alzheimer Medication'

 

LEIDEN, Netherlands, October 26, 2010 /PRNewswire/ -- Dutch researchers have discovered a possible key which might result in a medicine for Alzheimer's disease. "We have found brain cells which become extra active at a time when there are still no visible symptoms of the disease. Nevertheless, people are already ill", says brain researcher Dick Swaab. "It would be fantastic if we could simulate this activation process through medicines once the disease has progressed." The findings of the Dutch scientists, under the auspices of research institute TI Pharma, are due to be published in the reputable scientific magazine Brain.

Scientists examined the brain tissue of 49 deceased patients, in various stages of the disease. In the very earliest stage of the disease, patients did not appear to have any memory impairments or other symptoms of Alzheimer's disease. Under the microscope, however, signs of Alzheimer's are visible. Swaab: "The brain itself appears to compensate for the disease process; nearly 500 genes in the front part of the parahippocampal cortex then become extra active. These genes ensure that nerve cells are better able to communicate with each other, allowing people to continue to function well. As soon as these genes become less active, the memory impairments become apparent."

According to Swaab, this discovery is an important step on the road to finding effective medication. "We see these temporarily active genes as a pointer to a medicine. Once the disease has progressed to a more advanced stage, we can see whether we can reactivate the brain cells using medicines." Swaab adds that a medicine for Alzheimer's will only be a possibility for future generations.

Alzheimer's is the most common cause of dementia. Between sixty and seventy percent of patients suffer from this form of dementia. In Alzheimer's disease, the nerve cells in the brain and the connections between these cells break down, preventing the brain from functioning well. There are an estimated quarter of a million patients in the Netherlands; this number will double in the next forty years.

The research to which among others neuroscientists Dick Swaab, Joost Verhaagen and Koen Bossers from the Netherlands Institute for Neurosciences contribute is funded by Top Instituut Pharma. Other partners are the Netherlands Brain Bank, DNage and health care organization Abbott.

About Top Institute Pharma

Top Institute Pharma (TI Pharma) is a public-private partnership in which the academic and business world work together on innovative, multidisciplinary research targeted toward the improvement of the development of socially valuable medicines. The project portfolio is based on the clinical areas as described in the "Priority Medicines" report from the World Health Organization (WHO). These projects create knowledge that is important for the better, faster and less expensive development of valuable new medicines. For more information, please visit http://www.tipharma.com.


'/>"/>
SOURCE Top Institute Pharma
Copyright©2010 PR Newswire.
All rights reserved

Related biology technology :

1. Canopus Biopharma and Leading Chinese Researcher Team Up to Treat Avian Influenza, to Prevent Possible Pandemic
2. Denser, more powerful computer chips possible with plasmonic lenses that fly
3. Self-powered devices possible, says Texas A&M researcher
4. Bio-Matrix Scientific Group CEO Tells Wall Street Transcript That Positive Cash Flow Is Possible in 09; New Stem Cell Banking Facility Is Growth Vehicle Over the Next Two Years, Says CEO in Exclusive News Interview
5. New security and medical sensor devices made possible by metallic nanostructures
6. MMR Offers Free Surgical Masks to Call Attention to Importance of Personal Health Records in Preparing for Possible Swine Flu Pandemic
7. Practice makes perfect -- motor memory possible for neuroprosthetic control
8. NeoStem, Inc. is Certified by the State of New York as a Qualified Emerging Technology Company and Notifies Investors of Possible Tax Credit of up to 20%
9. Brazilian Sugarcane Industry Association Stresses Need for Brazils Government to Announce Ethanol Import Tariff Cut as Soon as Possible
10. BioSpec Global Solutions Inc. Enters into talks with possible Chinese partner
11. Researchers stretch a lackluster material into a possible electronics revolution
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/5/2016)... , Feb. 5, 2016 Australian-US drug discovery and ... today the appointment of a new Chairman, Mr John ... , effective immediately. James Garner , has ... Director and former Acting CEO, Mr Iain Ross , ... Director. --> James Garner , has also been ...
(Date:2/4/2016)... , ... February 04, 2016 ... ... presented by Bloomsburg University’s Digital Forensics Club, takes place February 5-6 at ... event features 20+ speakers and activities such as workshops and competitions for ...
(Date:2/4/2016)... , Feb. 4, 2016 ContraVir Pharmaceuticals, Inc. ... the development and commercialization of targeted antiviral therapies, announced ... Investor Conference 2016, to be held February 8-9, 2016, ... Group,s 2016 Disruptive Growth & Healthcare Conference, taking place ... 10-11, 2016. James Sapirstein , Chief Executive ...
(Date:2/4/2016)... (PRWEB) , ... February 04, 2016 , ... Many of ... for over 10 years. What sets them apart from other cuvette manufacturers is ... posted on their website. On top of this steady flow of inside information, ...
Breaking Biology Technology:
(Date:1/28/2016)... Synaptics (NASDAQ: SYNA ), a leading developer of human interface ... 31, 2015. --> --> ... percent compared to the comparable quarter last year to $470.5 million. ... million, or $0.93 per diluted share. --> ... of fiscal 2016 grew 9 percent over the prior year period ...
(Date:1/22/2016)... 2016 http://www.researchandmarkets.com/research/4lmf2s/global_behavioral ... the  "Global Behavioral Biometric Market 2016-2020" ... http://www.researchandmarkets.com/research/4lmf2s/global_behavioral ) has announced the ... Market 2016-2020"  report to their offering. ... http://www.researchandmarkets.com/research/4lmf2s/global_behavioral ) has announced the addition ...
(Date:1/20/2016)... , Jan. 20, 2016   MedNet Solutions ... the entire spectrum of clinical research, is pleased to ... MedNet,s significant achievements are the result of the company,s ... iMedNet eClinical , it,s comprehensive, easy-to-use and ... --> Key MedNet growth achievements in ...
Breaking Biology News(10 mins):