Navigation Links
Positive Study Results for Ceftaroline Phase III Clinical Study for the Treatment of Complicated Skin and Skin Structure Infections Presented at ICAAC / IDSA
Date:10/27/2008

agues showed that ceftaroline has the greatest overall in vitro bactericidal activity against community-associated MRSA (CA-MRSA), vancomycin-intermediate S. aureus (VISA), vancomycin-resistant S. aureus (VRSA) and daptomycin non-susceptible S. aureus (DNSSA) compared to vancomycin, daptomycin, clindamycin, linezolid, TMP/SMX, and ceftriaxone.(6)

--Spontaneous mutation frequency and serial passage resistance development studies with ceftaroline (CPT) (Poster C1-185)(7)

Dr. R. Hinshaw and colleagues evaluated the risk of ceftaroline resistance development using an in vitro model. There was no propensity for resistance development to ceftaroline when serially tested against important skin and community-acquired pneumonia pathogens, including methicillin-susceptible S. aureus (MSSA), MRSA, community-acquired MRSA (CA-MRSA), vancomycin-intermediate S. aureus (VISA), penicillin-susceptible S. pneumoniae (PSSP), penicillin-resistant S. pneumoniae (PRSP), and beta-lactamase-negative H. influenzae.(7)

About Complicated Skin and Skin Structure Infections (cSSSIs)

cSSSIs are caused by gram-positive bacteria, such as MRSA, and common gram-negative bacteria.(8) cSSSIs are among the most common infections treated in the hospital setting,(9) and MRSA infections, now the most frequent cause of cSSSI presenting to emergency departments in the United States (U.S.) and the cause of more than 18,000 deaths in 2005, are becoming more common in patients in both the hospital and community settings.(10)

According to the Centers for Disease Control and Prevention, about 70% of bacterial infections are resistant to at least one drug.(11) Many are resistant to multiple drugs making cSSSIs, especially due to MRSA, challenging to treat.(12) cSSSIs can become extremely serious, leading to hospitalization with increased risk for morbidity and mortality and increased healthcare costs.(11) In a study of patients in the emergency room with skin and skin-structure
'/>"/>

SOURCE Forest Laboratories, Inc.
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7 8

Related biology technology :

1. Poniard Announces Positive Incremental Efficacy and Safety Data from Phase 2 Picoplatin Trial in Patients With Metastatic Colorectal Cancer
2. Poniard Announces Positive Incremental Efficacy and Safety Data From Ongoing Phase 2 Picoplatin Trial in Hormone-Refractory Prostate Cancer
3. Positive Preclinical Data on Cell Therapy for Spinal Disc Repair Presented at 23rd Annual Meeting of the North American Spine Society
4. Nile Therapeutics Announces Positive Interim Data from Phase 2a Study of CD-NP in Patients with Heart Failure
5. BioMS Medicals relapsing-remitting multiple sclerosis trial receives positive review from Data Safety Monitoring Board
6. BioMS Medicals phase III U.S. multiple sclerosis trial receives positive safety review from Data Safety Monitoring Board
7. Cepheid Receives FDA Clearance for First On-Demand Diagnostic Test for Life-Threatening MRSA and Staphylococcus aureus From Patient Positive Blood Cultures
8. Kuvan Receives Positive Opinion From CHMP for European Approval
9. InspireMD Announces Enrollment of First Patients in the MGuard(TM) Acute Myocardial Infarction Clinical Trial Data Will be Used to Confirm Initial Positive Results
10. Tengion Scientists Publish Positive Preclinical Findings With Neo-Organ Demonstrating Long-term Durability and Growth With Skeletal Maturation
11. Repligen Announces Publication of Positive Results with Proprietary HDAC Inhibitor in Huntingtons Disease Model
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/19/2014)... The Latin American hardware encryption display ... America with analysis and forecast of revenue. This market ... expected to reach $2,366.8 million by 2018, at a ... through the TOC of the Latin American hardware encryption ... analysis provided. It also provides a glimpse of the ...
(Date:10/19/2014)... October 19, 2014 The Asia-Pacific ... market in Asia-Pacific with analysis and forecast of ... Asia Pacific Bromine Market report, to get an ... provides a glimpse of the segmentation in the ... tables and figures. , http://www.micromarketmonitor.com/market/asia-pacific-bromine-6741503144.html ...
(Date:10/19/2014)... The report "Chocolate, Cocoa Beans, Lecithin, Sugar and ... and Forecast (2011 - 2016)," analyzes the chocolate ... the major market drivers, restraints, and opportunities for the ... The global chocolate market is expected to grow from ... an estimated CAGR of 2.7% from 2011 to 2016. ...
(Date:10/19/2014)... According to market research report “Outdoor Wi-Fi Market ... Global Advancements, Forecasts and Analysis (2013 - 2018)", ... with analysis and forecasting of the global revenues. ... and the restrains for this market with the ... Browse 65 market data tables and 69 figures ...
Breaking Biology Technology:The Latin American hardware encryption display market is expected to reach $2,366.8 million by 2018 - New Report by MicroMarket Monitor 2The Latin American hardware encryption display market is expected to reach $2,366.8 million by 2018 - New Report by MicroMarket Monitor 3The Asia-Pacific Bromine Market is estimated to grow to $4,080.1 million by 2018 - New Report by MicroMarket Monitor 2The Asia-Pacific Bromine Market is estimated to grow to $4,080.1 million by 2018 - New Report by MicroMarket Monitor 3Chocolate Market Projected To Reach $98.3 Billion by 2016 - New Report by MarketsandMarkets 2Chocolate Market Projected To Reach $98.3 Billion by 2016 - New Report by MarketsandMarkets 3Chocolate Market Projected To Reach $98.3 Billion by 2016 - New Report by MarketsandMarkets 4Outdoor Wi-Fi Market (by Access Points, WLAN Controllers, Wireless gateways) Expected to Cross $37.2 Billion by 2018 - New Report by MarketsandMarkets 2Outdoor Wi-Fi Market (by Access Points, WLAN Controllers, Wireless gateways) Expected to Cross $37.2 Billion by 2018 - New Report by MarketsandMarkets 3Outdoor Wi-Fi Market (by Access Points, WLAN Controllers, Wireless gateways) Expected to Cross $37.2 Billion by 2018 - New Report by MarketsandMarkets 4
... Boston,Scientific Corporation (NYSE: BSX ) and ... Boston Scientific has completed its acquisition of CryoCor.,The ... 16.,Under the terms of the transaction, all remaining ... share in cash, for a total of,approximately $17.6 ...
... Ill., May 28 Abbott will present,at the ... June 10, 2008. Thomas C. Freyman, executive vice ... presentation on the,company at 3:20 p.m. Central time., ... will be accessible through,Abbott,s Investor Relations Web site ...
... MOUNTAINSIDE, N.J., May 28 National Stem Cell,Holding, Inc. ... taking steps to,change its name to Proteonomix, Inc. The ... Michael Cohen, President/CEO, stated: "Our new name reflects ... and development stage and,commencing the commercialization of our technologies. ...
Cached Biology Technology:Boston Scientific Completes Acquisition of CryoCor 2Boston Scientific Completes Acquisition of CryoCor 3National Stem Cell Holding, Inc. Announces the Change of Its Name to Proteonomix, Inc. 2National Stem Cell Holding, Inc. Announces the Change of Its Name to Proteonomix, Inc. 3
(Date:10/17/2014)... regarding Ebola is critical and pertinent for practicing physicians ... outbreak and epidemic. The Journal, Disaster Medicine and ... Ebola Virus and Public Health, to surround the public, ... critical societal moment. , On October 17, the ... . The primer was prepared by Dr. Eric Toner, ...
(Date:10/16/2014)... Mary,s Virginia Institute of Marine Science have received ... Agency to identify the streams and wetlands most ... to help local governments and citizens conserve these ... a dataset of tidal-marsh observations first gathered by ... historical baseline can today,s researchers accurately map the ...
(Date:10/16/2014)... Post-menopausal women experienced improvements in vaginal atrophy, with ... bleeding, after 12 weeks of daily 10 milligram ... nutritional supplement previously shown to help relieve certain ... study reported in a poster at the North ... , "These data documented improved vaginal epithelium, without ...
Breaking Biology News(10 mins):EPA grant will help localities conserve headwater wetlands 2EPA grant will help localities conserve headwater wetlands 3S-equol supplements associated with improved measures of reproductive health in postmenopausal women 2
... collaboration between BBSRC, EPSRC and industry has today (9 ... of extracting valuable chemicals from the co-products of grain ... produces low-value derivatives that are often sold as animal ... find ways of processing these by-products to yield chemicals ...
... Canada Large-Scale Applied Research Project Competition, which as a ... the country, the researchers in Ontario will be focusing ... identifying genes or proteins for drug targets, and the ... diseases. The first project, with a budget of ...
... Advances in HIV/AIDS Prevention and Treatment" is a one-day ... issues facing researchers working towards the development of an ... The symposium will cover epidemiological challenges, developments in HIV ... imaging of viruses crossing the mucosal barrier, the latest ...
Cached Biology News:Public and private sectors unite to make more of brewing by-products 2OGI genomics researchers awarded $23 million 2OGI genomics researchers awarded $23 million 3
... is a 16 amino acid (amino acids 3-18) synthetic peptide ... The sequence of this peptide is (amino to carboxy terminus): ... V - K - L - R - A - ... K(18). This peptide may be used for neutralization ...
... standard microarray image analysis software because of ... tools, visualizations, automation capabilities, performance and ease ... every GenePix scanner, and it also imports ... types of arrays. A wide range of ...
... Package Superior Protein Detection and Quantitation ... 2D Proteomic Imaging System is a highly ... general life science research applications. ProXPRESS 2D ... all dyes in the UV and VIS ...
... Description: ,Kit containing Dermal Fibroblasts ... containing 20% FBS and 10% DMSO at ... mL) of optimized medium.This cell culture is ... guaranteed to provide an additional 6 months ...
Biology Products: