Navigation Links
Positive Results Reported for Phase I Clinical Trial at UCLA for the Treatment of ADHD in Children Using External Trigeminal Nerve Stimulation (eTNS)
Date:5/20/2013

LOS ANGELES, May 20, 2013 /PRNewswire/ -- Today, at the American Psychiatric Association (APA) Meeting in San Francisco, James McGough , M.D., M.S., principal investigator and Professor of Clinical Psychiatry at the Semel Institute for Neuroscience and Human Behavior and David Geffen School of Medicine at the University of California Los Angeles (UCLA), and director of clinical teaching programs in both Child and Adolescent Psychopharmacology and ADHD at UCLA, presented the results of a Phase I open-label pediatric clinical trial. The study commenced in November 2011 and investigated the effects of external Trigeminal Nerve Stimulation (eTNS™) on Attention Deficit Hyperactivity Disorder (ADHD) as stand-alone monotherapy (i.e., without use of medications of any kind).

Mean improvements of over 40% were recorded after 4 weeks and over 45% after 8 weeks (both results p<0.001 versus baseline) using the total scores of the a priori primary outcome metric, the clinician-rated ADHD Rating Scale (ADHD-RS). These results are in line with improvements reported in other clinical trials that used stimulant medications, and form the basis for proceeding with larger clinical trials under double blind conditions to better establish its effects.  In the eTNS trial, 20 subjects, aged 7 to 14 years with APA Diagnostic and Statistical Manual-IV (DSM-IV) diagnosis of ADHD, had stimulating electric patch electrodes placed on their foreheads on a nightly basis while asleep.  Their ADHD symptoms were assessed every four weeks.  eTNS was well tolerated and no serious adverse events occurred during the 8-week treatment period.

The investigator-initiated study was funded entirely by NeuroSigma and conducted at UCLA.  Project design, data collection, analyses, and conclusions, were solely the work of the UCLA study investigator
'/>"/>

SOURCE NeuroSigma
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related biology technology :

1. ChemoCentryx Presents Positive Results for Novel CCR2 Inhibitor in Preclinical Models of Diabetic Nephropathy at the 44th Annual Meeting of the American Society of Nephrology
2. Positive Clinical Study Results for BSPs HyperQ Technology
3. Echo Therapeutics Announces Positive Results of Clinical Trial of its Symphony® Transdermal Continuous Glucose Monitoring (tCGM) System in Patients With Type 1 and Type 2 Diabetes
4. Silence Therapeutics Announces Positive Outcome From Oral Hearing at the European Patent Office
5. Metabolex Announces Positive Results From its Clinical Study of Arhalofenate in Combination With Febuxostat
6. Puma Biotechnology Announces Positive PB272 (Neratinib) Phase II Data at CTRC-AACR San Antonio Breast Cancer Symposium
7. Silence Therapeutics Announces Positive Response by USPTO that Affirms Validity of Four Foundational RNAi Patents
8. Idenix Reports Positive Interim Data for HCV Nucleotide Inhibitor, IDX184
9. Xention Reports Positive Phase 1 Data for New Atrial Fibrillation Drug
10. Echo Therapeutics to Present Positive Clinical Trial Results at the 72nd Scientific Sessions of the American Diabetes Association
11. Syndax Pharmaceuticals Announces Start of Phase 1/2 Study of Entinostat in Combination with Lapatinib in HER2-Positive Metastatic Breast Cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/24/2014)... and NEW YORK , Dec. 23, ... open-label pilot study of mazindol in children with attention ... Therapy in December 2014 . The ... children with attention deficit/hyperactivity disorder" ( Konofal et al, ... Dec 1;8:2321-2332. eCollection 2014 ) shows that mazindol ...
(Date:12/22/2014)... GenomeDx Biosciences today announced that a new ... genomic test for prostate cancer, was able to predict ... radical prostatectomy without adjuvant therapy. Although rapid metastasis in ... tumor genomics to identify these men who have a ... advance. The study has been published online by ...
(Date:12/19/2014)... December 19, 2014 Bioject Medical ... and manufacturer of needle-free injection technology, today announced ... Immunomic Therapeutics, Inc. (“ITI”) for ITI to use ... its LAMP™ vaccine platform. , In the ... Worldwide license to the Biojector®-2000 that triggers based ...
(Date:12/19/2014)... REDWOOD CITY, Calif. , Dec. 19, 2014 ... , USA) announced today that they have been ... Technologies 1,2 is a privately held company that ... processing of next generation sequencing (NGS) data for the ... into the Roche Sequencing Unit, and will continue to ...
Breaking Biology Technology:Redefining ADHD: A New Approach & A Shift of Paradigm in ADHD Therapeutics 2Redefining ADHD: A New Approach & A Shift of Paradigm in ADHD Therapeutics 3Study Published in European Urology Shows that the Decipher Prostate Cancer Classifier is Predictive of Rapid Metastasis in High-Risk Men who have had Prostate Surgery 2Study Published in European Urology Shows that the Decipher Prostate Cancer Classifier is Predictive of Rapid Metastasis in High-Risk Men who have had Prostate Surgery 3Bioject and Immunomic Therapeutics Enter into an Agreement for License of Needle-Free Technology for LAMP-vax Vaccines 2Bioject and Immunomic Therapeutics Enter into an Agreement for License of Needle-Free Technology for LAMP-vax Vaccines 3Bina Technologies is acquired by Roche. 2Bina Technologies is acquired by Roche. 3
... challenges , ,MADISON The white board in the ... their condition is a familiar scene in many hospitals. But ... best interest of the patient but still providing information to ... of a lecture given by Dennis Dassenko , UW ...
... of Wisconsin-Madison Department of Educational Psychology has teamed up ... Co-Lab to create new worlds in which people ... Department's Learning Sciences Program studies how human ... in UW-Madison's School of Education. "We have made digital ...
... EMD Biosciences Inc. , a supplier of premium ... it has formed a strategic partnership with The ... automation for life science applications. , ,This partnership ... and validate EMDs products on the Piccolo system, TAP's ...
Cached Biology Technology:The challenges of maintaining patient privacy and delivering secure clinical information 2The challenges of maintaining patient privacy and delivering secure clinical information 3University of Wisconsin team creates learning games 2University of Wisconsin team creates learning games 3EMD Biosciences partners with European biotech company 2
(Date:12/19/2014)... 2014 Research and Markets ( http://www.researchandmarkets.com/research/86ncd6/micro_market ... Market Monitor: North America Perimeter Security Systems Market" ... http://photos.prnewswire.com/prnh/20130307/600769 The North American perimeter security ... 3.6% from 2014 to 2019. Although the U.S. market ... Canada is expected to grow at a ...
(Date:12/17/2014)... BELVOIR, Va. , Dec. 15, 2014 /PRNewswire-USNewswire/ ... efforts to make it easier to detect and ... chain. Today the agency started performing ... The capability will validate the authenticity of purchased ... chain. The new quality control measures will be ...
(Date:12/17/2014)... -- Automation is fundamentally transforming the travel experience and ... borders. Over the past decade, ePassports, biometric readers, ... to self process through border control via eGates ... increasing number of airports, seaports, and land borders ... Maxine Most , Principal at Acuity Market ...
Breaking Biology News(10 mins):Micro Market Monitor: North America Perimeter Security Systems Market (Intrusion Detection Sensor, Video Surveillance, Communication/Alarm and Notification, Access Control System) 2Micro Market Monitor: North America Perimeter Security Systems Market (Intrusion Detection Sensor, Video Surveillance, Communication/Alarm and Notification, Access Control System) 3Defense Logistics Agency Launches DNA Marking Capability to Strengthen Microcircuit Supply Chain 2Defense Logistics Agency Launches DNA Marking Capability to Strengthen Microcircuit Supply Chain 3Automated Border Control (ABC) Transforms the Global Travel Experience With More Than 2500 ABC eGates and APC Kiosks Deployed In Airports, Seaports, and Land Borders Worldwide 2
... May 4 Strengthening its position as a ... PKI-based ePassport technology to help the Malaysian government (Jabatan Imigresen Malaysia) migrate ... , , , ... always prided itself on being at the forefront of border security," said ...
... available in German . , The hairs on ... 10 per cent decrease in fuel consumption. The plant has the ... water. Researchers at the University of Bonn, Rostock and Karlsruhe now ... the fern does this. Their results can possibly be used for ...
... Granada (UGR) have studied the natural history and conservation status ... balansae in Europe, a thorny bush that can grow ... be exclusive to Morocco. The team of scientists is calling ... of threatened species. In 2006, a research team from ...
Cached Biology News:Entrust Technology, Expertise Called on for Malaysian ePassport Project 2Entrust Technology, Expertise Called on for Malaysian ePassport Project 3Entrust Technology, Expertise Called on for Malaysian ePassport Project 4Bionic coating could help ships to economize on fuel 2Polygala balansae, a new bush to Europe, at risk of extinction in Spain 2
... Sigmas 10 Capillary Electrophoresis Running Buffer ... and high throughput demands of todays sequencing ... supplier of TBE to the gel-based sequencing ... large scale capacity to meet your buffer ...
... knockdown of all human, mouse, and ... Genomewide, predesigned siRNAs for a ... , Ready-to-use, convenient matching solutions for ... Cost-effective RNAi and downstream analysis ...
... Excalibur™ mid-, near- and far-infrared range FT-IR ... performance in their class. Yet all this ... Features: Highest-energy throughput: Having a larger ... compared to other conventional FT-IRs provides 300%,larger ...
... Rapid-Screen cDNA Library Panels were designed for ... sets of PCRs to identify the desired ... performed in a 96-well "Master Plate," where ... clones. Having identified the positive well(s) by ...
Biology Products: