Navigation Links
Positive Preclinical Data on Cell Therapy for Spinal Disc Repair Presented at 23rd Annual Meeting of the North American Spine Society
Date:10/16/2008

ST. LOUIS, Oct. 16 /PRNewswire/ -- ISTO Technologies, Inc., a privately held orthobiologics company, today announced positive preclinical data related to its NuQu(TM) injectable cell-based therapy for spinal disc repair. The data was presented in Toronto, Canada at the 23rd Annual Meeting of the North American Spine Society. Studies carried out at the University of California San Francisco (UCSF) Department of Orthopedics were designed to investigate potential applications of ISTO's core cell-based platform technology (juvenile cartilage cells) as a non-invasive procedure for treatment of degenerative intervertebral disc. In these pre-clinical studies, the disc nucleus from adult pigs was removed and replaced with juvenile chondrocytes in a protein gel carrier.

"We are encouraged by the results of the UCSF preclinical studies and we believe ISTO's cell-based therapy may offer a breakthrough for early non- surgical intervention for patients suffering from back pain," said Mitchell Seyedin, Ph.D., President & CEO.

"Because the disc environment is only conducive to highly specialized cells, the purpose of this preclinical study was to evaluate whether juvenile cartilage cells can effectively replace and regenerate cartilage in the nucleus," said Jeffrey Lotz, Ph.D., Director of the Orthopaedic Bioengineering Laboratory at UCSF. "We are very encouraged by the fact, that in several animal studies, these cells have shown the ability to generate cartilage in the disc nucleus in a predictable and consistent basis," said Dr. Lotz.

NuQu is being developed as a non-invasive treatment for degenerative disc disease for patients who are suffering from low back pain and have failed to respond to conservative therapy. The economic and social impact of back pain due to disc degeneration places a tremendous burden on patients, the healthcare system and the overall economy. Today, there is no effective treatment for degenerative disc disease.

Disc de
'/>"/>

SOURCE ISTO Technologies, Inc.
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2

Related biology technology :

1. Nile Therapeutics Announces Positive Interim Data from Phase 2a Study of CD-NP in Patients with Heart Failure
2. BioMS Medicals relapsing-remitting multiple sclerosis trial receives positive review from Data Safety Monitoring Board
3. BioMS Medicals phase III U.S. multiple sclerosis trial receives positive safety review from Data Safety Monitoring Board
4. Cepheid Receives FDA Clearance for First On-Demand Diagnostic Test for Life-Threatening MRSA and Staphylococcus aureus From Patient Positive Blood Cultures
5. Kuvan Receives Positive Opinion From CHMP for European Approval
6. InspireMD Announces Enrollment of First Patients in the MGuard(TM) Acute Myocardial Infarction Clinical Trial Data Will be Used to Confirm Initial Positive Results
7. Tengion Scientists Publish Positive Preclinical Findings With Neo-Organ Demonstrating Long-term Durability and Growth With Skeletal Maturation
8. Repligen Announces Publication of Positive Results with Proprietary HDAC Inhibitor in Huntingtons Disease Model
9. Positive SPA Reply From the FDA for TopoTargets Pivotal Trial With Belinostat in PTCL
10. Ondine Announces Presentation of Positive Clinical Trial Results at the American Academy of Periodontologys 94th Annual Meeting
11. Palatin Technologies, Inc. Reports Positive Results of Phase 2a Clinical Study with PL-3994 for the Treatment of Heart Failure

Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/5/2009)... RANCHO CORDOVA, Calif., Nov. 5 /PRNewswire-FirstC...ading supplier of innovative products for processi...sults for the first quarter of fiscal 2010. ,, ...any reported revenues of $5.2 million, a 15 percen...rst quarter a year ago. The Company said the key c...
(Date:11/5/2009)... LYNBROOK, N.Y., Nov. 5 ...a biopharmaceutical company developing first-in-cl...s financial results for the third quarter ended Se...that, in September of this year, the FDA,s Arthrit...a vote of 12-0, the approval of XIAFLEX(TM) for th...
(Date:11/5/2009)... SAN DIEGO, CA, November 5, 2009 /PRNewswire-First... focused on using proprietary taste receptor-based... for the food, beverage, and ingredient supply ind...orted financial results for the third quarter ende...for the third quarter of 2009, compared to $4.0 mi...
(Date:11/5/2009)... PLYMOUTH MEETING, Pa., Nov. 5 /PRNewswire-Asi... BJGP ) ("BMP Sunstone" or the "Company") today an...arter 2009 financial results on,Monday, November 9...mpany will hold a conference call at 5:00 pm ET on...sults. Listeners may access the call by,dialing 1...
Breaking Biology Technology:ThermoGenesis Reports 15 Percent Increase in First Quarter Revenues; Improved Bottom Line 2ThermoGenesis Reports 15 Percent Increase in First Quarter Revenues; Improved Bottom Line 3ThermoGenesis Reports 15 Percent Increase in First Quarter Revenues; Improved Bottom Line 4ThermoGenesis Reports 15 Percent Increase in First Quarter Revenues; Improved Bottom Line 5ThermoGenesis Reports 15 Percent Increase in First Quarter Revenues; Improved Bottom Line 6ThermoGenesis Reports 15 Percent Increase in First Quarter Revenues; Improved Bottom Line 7ThermoGenesis Reports 15 Percent Increase in First Quarter Revenues; Improved Bottom Line 8BioSpecifics Technologies Corp. Reports Third Quarter 2009 Financial Results 2BioSpecifics Technologies Corp. Reports Third Quarter 2009 Financial Results 3BioSpecifics Technologies Corp. Reports Third Quarter 2009 Financial Results 4BioSpecifics Technologies Corp. Reports Third Quarter 2009 Financial Results 5SENOMYX ANNOUNCES CORPORATE UPDATE AND THIRD QUARTER 2009 FINANCIAL RESULTS 2SENOMYX ANNOUNCES CORPORATE UPDATE AND THIRD QUARTER 2009 FINANCIAL RESULTS 3SENOMYX ANNOUNCES CORPORATE UPDATE AND THIRD QUARTER 2009 FINANCIAL RESULTS 4SENOMYX ANNOUNCES CORPORATE UPDATE AND THIRD QUARTER 2009 FINANCIAL RESULTS 5SENOMYX ANNOUNCES CORPORATE UPDATE AND THIRD QUARTER 2009 FINANCIAL RESULTS 6SENOMYX ANNOUNCES CORPORATE UPDATE AND THIRD QUARTER 2009 FINANCIAL RESULTS 7SENOMYX ANNOUNCES CORPORATE UPDATE AND THIRD QUARTER 2009 FINANCIAL RESULTS 8SENOMYX ANNOUNCES CORPORATE UPDATE AND THIRD QUARTER 2009 FINANCIAL RESULTS 9SENOMYX ANNOUNCES CORPORATE UPDATE AND THIRD QUARTER 2009 FINANCIAL RESULTS 10SENOMYX ANNOUNCES CORPORATE UPDATE AND THIRD QUARTER 2009 FINANCIAL RESULTS 11SENOMYX ANNOUNCES CORPORATE UPDATE AND THIRD QUARTER 2009 FINANCIAL RESULTS 12SENOMYX ANNOUNCES CORPORATE UPDATE AND THIRD QUARTER 2009 FINANCIAL RESULTS 13SENOMYX ANNOUNCES CORPORATE UPDATE AND THIRD QUARTER 2009 FINANCIAL RESULTS 14BMP Sunstone to Report Third Quarter 2009 Financial Results 2
...l implants placed will use guided surgery ...up, WALTHAM, Mass., May 6 According to Millenniu...2008 report, the incorporation of,guided surgery t...ease,dramatically over the next few years and by 2...e advantage of some form of guided surgery,technol...
...h Programs Supported by a Grant from Otsuka ...VILLE, Md., May 6 The American Psychiatric,Founda... and one individual,as the recipients of the fifth...ealth. The awards were presented at the 2008 APF A...n or individual was presented a plaque,along with ...
...rex, Inc. (Nasdaq:,MEDX) announced today that it i... Healthcare Conference at 1:00 p.m. EDT on Tuesday...will be available in the Investor,Relations sectio...m . An archived,edition of the presentation will b... Medarex is a biopharmaceutical company focused on...
Other Biology Technology:Guided Surgery Technology Gaining Popularity in the Dental Implant Market 2American Psychiatric Foundation Announces Recipients of 2008 Awards for Advancing Minority Mental Health 2American Psychiatric Foundation Announces Recipients of 2008 Awards for Advancing Minority Mental Health 3American Psychiatric Foundation Announces Recipients of 2008 Awards for Advancing Minority Mental Health 4American Psychiatric Foundation Announces Recipients of 2008 Awards for Advancing Minority Mental Health 5
(Date:11/4/2009)...deciphered the DNA codes, or genomes, of the famed...ed The Genome 10K Project, an international effort...s on 10,000 species of animals for conducting comp...be achieved. , Participating in The Genome 10K p... 5, 2009 issue of the Journal of Heredity , are 7...
(Date:11/4/2009)...RNewswire-FirstCall/ -- Aware, Inc. (Nasdaq: AWRE... biometrics software, today reported financial res...09. ,, Michael Tzannes, Aware,s Chairman and ...announced an agreement to sell our DSL and home ne...miconductor company being spun out of Infineon. T...
(Date:11/4/2009)... at the University of North Carolina at Chapel Hil...nia, San Francisco have developed and experimental...es for existing drugs. , The researchers develop...r the structures of all known drugs are to the nat...nds -- of disease targets within the cell. In a st...
Breaking Biology News(10 mins):Singapore scientists join international study of 10,000 vertebrates' genomes 2Aware, Inc. Reports Third Quarter 2009 Financial Results 2Aware, Inc. Reports Third Quarter 2009 Financial Results 3Aware, Inc. Reports Third Quarter 2009 Financial Results 4Aware, Inc. Reports Third Quarter 2009 Financial Results 5Aware, Inc. Reports Third Quarter 2009 Financial Results 6Aware, Inc. Reports Third Quarter 2009 Financial Results 7Study points to new uses, unexpected side effects of already existing drugs 2DaVitas Patient Centric Modalities Offer Students with Kidney Disease More Choices 56685 1DaVitas Patient Centric Modalities Offer Students with Kidney Disease More Choices 56685 2FDA Panel Backs Giving HPV Vaccine Gardasil to Young Males 56683 1FDA Panel Backs Giving HPV Vaccine Gardasil to Young Males 56683 2FDA Panel Backs Giving HPV Vaccine Gardasil to Young Males 56683 3FDA Panel Backs Giving HPV Vaccine Gardasil to Young Males 56683 4Link found between common sexual infection and risk of aggressive prostate cancer 56681 1Link found between common sexual infection and risk of aggressive prostate cancer 56681 2
... the frontier between Uganda and the Democratic Re...d in a national park and wildlife preserve on the ...cattle have settled in an adjoining Ugandan park. ...uld potentially support more than 900 individuals ...esearch but only if immediate conservation steps ...
...fornia, Davis have discovered that a prototype dru...n causes of heart failure. , Heart failure, whic...roughout the body, affects 5 million people in the...00 deaths each year. , The research in the labor... Chiamvimonvat, Department of Cardiovascular Medic...
...ty of Bath and London,s Natural History Museum has... of dinosaurs is remarkably complete. , Evolutio...n of prehistoric plants and animals: firstly they ...n chronological order according to the age of the ...ndly they observe and classify the characteristics...
Other Biology News:Research uncovers surprising lion stronghold in war-torn central Africa 2Research uncovers surprising lion stronghold in war-torn central Africa 3UC Davis research shows that newly discovered drug reduces heart enlargement 2Dinosaur fossils fit perfectly into the evolutionary tree of life 2
.... Optimized for the rapid and efficient cloning of...es traditional TA cloning approaches by offering c...any as 25-fold more positive clones.Amplicons gene...e fully compatible.High efficiency cloning, no req...
GeneAmp High Fidelity PCR from Applied Biosystems
Guanylate Cyclase Blocking Peptide from Cayman Chemical
Expansion and Cryopreservation of Cells from Meridian Life Science, Inc.
Biology Products: