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Poniard Pharmaceuticals to Present Final Data from Picoplatin Phase 1 Clinical Trials at American Association for Cancer Research's 100th Annual Meeting

-- Phase 1 Data from Colorectal Cancer and Oral Picoplatin Trials To Be Presented --

SOUTH SAN FRANCISCO, Calif., April 14 /PRNewswire-FirstCall/ -- Poniard Pharmaceuticals, Inc. (Nasdaq: PARD), a biopharmaceutical company focused on oncology, today announced that the Company will present final data from two Phase 1 clinical trials of picoplatin, the Company's lead product candidate, at poster sessions during the American Association for Cancer Research 100th Annual Meeting 2009 at the Colorado Convention Center in Denver. The Company will present efficacy and safety data from its Phase 1 trial of picoplatin in colorectal cancer (CRC) and bioavailability data from its Phase 1 trial of an oral formulation of picoplatin.

    Details are as follows:

    A Phase 1 study of picoplatin in combination with 5-fluorouracil and
    leucovorin (FOLPI) for colorectal cancer (CRC): Comparison of two
    picoplatin schedules
    Abstract #3578
    Earhart R, Gladkov OA, Cheporov SV, Biakhov MY, Manikhas B, Berdov B,
    Tjulandin S, Breitz H, De Jager R.
    Tuesday, April 21, 8:00 a.m. MDT
    Clinical Research 11 Session
    Hall B-F, Poster Section 30

    A Phase 1 randomized crossover oral picoplatin bioavailability
    pharmacokinetics and pharmacodynamics study
    Abstract #3594
    Phillips A, Saleh M, Yee L, Sharma S, Houston S, Karlin D, Breitz H,
    DeJager R, Earhart R.
    Tuesday, April 21, 8:00 a.m. MDT
    Clinical Research 12
    Hall B-F, Poster Section 31

About Poniard Pharmaceuticals

Poniard Pharmaceuticals, Inc. is a biopharmaceutical company focused on the development and commercialization of innovative oncology products to impact the lives of people with cancer. Picoplatin, the Company's lead platform product candidate, is a new generation platinum chemotherapy. To date, clinical studies suggest that picoplatin has an improved safety profile relative to existing platinum-based cancer therapies. Picoplatin is designed to overcome platinum resistance associated with chemotherapy in solid tumors, and is being studied in multiple cancer indications, combinations and formulations. Clinical trials of intravenous picoplatin include a Phase 3 trial in small cell lung cancer and Phase 2 trials in metastatic 2 colorectal and castration-resistant (hormone refractory) prostate cancers. The Company also is conducting a clinical trial of oral picoplatin in solid tumors. For additional information please visit

(C) 2009 Poniard Pharmaceuticals, Inc. All Rights Reserved.

Poniard and Poniard Pharmaceuticals are trademarks of Poniard Pharmaceuticals, Inc.

SOURCE Poniard Pharmaceuticals, Inc.
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