Navigation Links
Polaris Group Announces Positive Results for Phase 2 Study of ADI-PEG 20 in Malignant Pleural Mesothelioma
Date:10/28/2013

to treat cancers, especially those carrying a major metabolic defect that renders such cancer cells, unlike normal cells, unable to internally synthesize arginine. Because arginine is one of the 20 amino acids that are essential for protein synthesis and survival of cells, it is believed these cancer cells become dependent upon the external supply of arginine to survive and grow. ADI-PEG 20 is designed to systemically deplete the external supply of arginine, which causes arginine-dependent cancer cells to die while leaving the normal cells unharmed. Multiple cancers have been reported to have a high degree of arginine-dependency.

About Polaris Group

Polaris Group is a privately held biopharmaceutical company that specializes in the research and development of protein drugs to treat cancer and other debilitating diseases. The company's lead therapeutic, ADI-PEG 20, is currently being evaluated in a pivotal Phase 3 trial for hepatocellular carcinoma. Polaris Group is also investigating ADI-PEG 20 as a treatment for other cancers. In addition to the ADI-PEG 20 program, Polaris Group is researching and developing other biotherapeutic agents and is advancing a small molecule drug program that utilizes a rational structure-based approach to design novel compounds that inhibit the biological function of cancer-related protein targets.

For additional information please visit www.polarispharma.com


'/>"/>
SOURCE Polaris Group
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2

Related biology technology :

1. Polaris Group Files New IND for ADI-PEG 20 in Breast Cancer
2. ePharmaSolutions To Acquire Global Patient Recruitment Firm Polaris BioPharma
3. KEW Group Launches CancerPlex(SM) Assay to Bring State-of-the-Art Genomic Testing to Community Oncologists
4. Consolidation, Patent Loses, Weak R&D Productivity Depress ITO Transactions in Life Sciences Segment: Everest Group Annual Report
5. WIRB-Copernicus Group Leaders Speak at Global Clinical Research Summit in South Korea
6. Global Stem Cells Group, Inc. Announces Worldwide Alliance with EmCyte Corp. to Promote In-office Regenerative Medicine Solutions
7. FarHawk Marketing Services Represents IonBench™ and MS Noise™ at the Greater Boston Mass Spectrometry Discussion Group Corporate Night October 3rd
8. Reimbursement Marketing Agency Element Marketing Group Inc. Opens New Office in Irvine, California
9. Dennis R. Hill, MD to Speak at the American Cancer Society Man-to-Man Support Group to Discuss HDR Brachytherapy for Prostate Cancer Treatment
10. Bangkok Hospital Group Selects ClinicalKey to Enhance Medical Practice and Improve Patient Care
11. The Arrow Group of Animal Hospitals in Central Arizona Partners with Vet-Stem, Inc. to Bring Stem Cell Therapy to Their Patients
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/28/2015)... ... August 28, 2015 , ... Proove Biosciences , ... International Spine Intervention Society’ s 23rd Annual Scientific Meeting (ASM). The ... With a focus on evidence-based research and clinical application, the event gathered industry ...
(Date:8/27/2015)... ... August 27, 2015 , ... The Kansas City Animal Health ... animal health companies to hear from animal health companies with the newest technology. ... licensing agreements or distribution contracts. This meeting is one of the only ...
(Date:8/27/2015)... PARK, Calif. , Aug. 27, 2015  Asterias ... in the emerging field of regenerative medicine, today announced ... investor conferences in the month of September.  ... will present at Rodman & Renshaw,s 17th Annual Global ... ET/7:25am PT at the St. Regis Hotel in ...
(Date:8/27/2015)... ... August 27, 2015 , ... METTLER TOLEDO's web-based EasyFinder™ ... product choices to a manageable shortlist of bench and floor scales and terminals. ... fit best with the customer’s industry and application. , Side-by-side product comparisons ...
Breaking Biology Technology:Proove Biosciences Presents New Research Study at the International Spine Intervention Society’s Annual Scientific Meeting 2Proove Biosciences Presents New Research Study at the International Spine Intervention Society’s Annual Scientific Meeting 3Proove Biosciences Presents New Research Study at the International Spine Intervention Society’s Annual Scientific Meeting 4VetStem Biopharma, Inc. Among Seventeen Companies Selected to Present at the KC Animal Health Investment Forum on September 1st 2015 2VetStem Biopharma, Inc. Among Seventeen Companies Selected to Present at the KC Animal Health Investment Forum on September 1st 2015 3Asterias Biotherapeutics to Present at Upcoming Investor Conferences 2METTLER TOLEDO Updates Online Scale Selection Tool 2
... Verenium Corporation (Nasdaq: VRNM ), ... high-performance industrial enzyme solutions, today announced that it ... a high performance enzyme for the saccharification of ...  The DELTAZYM® GA L-E5 enzyme has demonstrated high ...
... a three-hospital health system providing care to ... management system provided by Surgical Information Systems ... into the hospitals, existing Siemens Soarian® system ... and drive business results. (Logo: ...
... MISSISSAUGA, ON, Sept. 29 /PRNewswire-FirstCall/ - YM BioSciences ... Pulmokine Inc. (Slingerlands, New York), a licensee of ... awarded two National Institutes of Health (NIH) Small ... more than US$650,000, are Phase I awards to ...
Cached Biology Technology:Verenium Launches DELTAZYM® GA L-E5 Enzyme for Fuel Ethanol Production 2Verenium Launches DELTAZYM® GA L-E5 Enzyme for Fuel Ethanol Production 3Susquehanna Health Selects Perioperative and Anesthesia Automation Solution from Surgical Information Systems 2Susquehanna Health Selects Perioperative and Anesthesia Automation Solution from Surgical Information Systems 3Susquehanna Health Selects Perioperative and Anesthesia Automation Solution from Surgical Information Systems 4YM BioSciences licensee Pulmokine awarded NIH funding to develop small molecule drugs for pulmonary hypertension 2YM BioSciences licensee Pulmokine awarded NIH funding to develop small molecule drugs for pulmonary hypertension 3
(Date:7/31/2015)... La 10e Conférence internationale sur la ... le BGI du 22 au 25 octobre 2015 ... La conférence célèbre son 10e anniversaire ... est devenue l,une des réunions annuelles mondiales les ... c,est aussi la plus dynamique, la plus enthousiaste ...
(Date:7/31/2015)... Jul. 31, 2015 NXT-ID, Inc. (NASDAQ: NXTD ... focused on the growing mobile commerce market and creator ... filed provisional patent 62/198989 for ELECTRONIC CRYPTO-CURRENCY ... a method to advance crypto-currencies such as Bitcoin into ... common, uniform way to manage all payments.  ...
(Date:7/27/2015)... , July 27, 2015  Synaptics Inc. (NASDAQ: ... interface solutions, today announced that Huawei has selected ... solution for its stylish smartwatch. Huawei chose the ... reliability, low power and highly responsive human interface ... Huawei designers also required a classic round watch ...
Breaking Biology News(10 mins):La 10e International Conference on Genomics (ICG-10) doit s'ouvrir en octobre 2La 10e International Conference on Genomics (ICG-10) doit s'ouvrir en octobre 3NXT-ID Patents Electronic Crypto-Currency Management Technology 2NXT-ID Patents Electronic Crypto-Currency Management Technology 3NXT-ID Patents Electronic Crypto-Currency Management Technology 4Synaptics Touchscreen Solution Powers New Huawei Watch 2Synaptics Touchscreen Solution Powers New Huawei Watch 3
... . , A tip about a folk ... off bugs has led to the discovery of insect-repelling ... identified components of Jatropha curcas seed oil ... Agricultural Research Service (ARS) Natural Products Utilization Research Unit ...
... Approximately one-third of Americans take a daily multivitamin, but little ... Now, new research from Brigham and Women,s Hospital (BWH) ... of cardiovascular disease in men. A similar BWH study, ... man,s risk of cancer by 8 percent. The cardiovascular ...
... move their facial whiskers back and forth about eight times ... acquire this sense? And if they can, what could understanding ... about how humans normally sense? At the Weizmann Institute, researchers ... of blindfolded volunteers and asking them to carry out a ...
Cached Biology News:Daily multivitamin use does not reduce cardiovascular disease risk in men 2Learning a new sense 2Learning a new sense 3
... catalyzes the degradation of single-stranded DNA and ... While the nuclease prefers ssDNA over dsDNA ... enzyme degrades double-stranded DNA from both ends ... for transcript mapping studies (3,4), for flushing ...
... The S.c. EasyComp Transformation Kit is ... Saccharomyces cerevisiae cells. Advantages over commonly ... formation or LiCl methods include:- Cells can ... 30 minutes - Competent cell preparation and ...
Endomorphin-2. Cross reactivity: Endomorphin-1 3%, Met-enkephalin <0.03%, Leu-enkephalin <0.01% and beta-Endorphin <0.01%....
...
Biology Products: