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Piramal Imaging Announces the Acceptance for Review of [18F] florbetaben by the FDA and EMA for the Visual Detection of beta-amyloid in Alzheimer's Disease
Date:3/21/2013

e United States and Europe. The company owns and operates a network of 54 PET isotope facilities worldwide, a network that is unique in both size and scope. Dehareng said, "We believe our network of PET isotope facilities is well positioned to maximize patient access to [18F] florbetaben and is strongly committed to providing our customers and their patients with the best quality product and service possible."

Notes to the editors:

About florbetaben

[18F] florbetaben is an 18F-labeled tracer for use in positron emission tomography (PET) which specifically binds to beta-amyloid deposits in the brain, a key pathological hallmark in Alzheimer's disease. A Phase III trial presented for the first time at the annual meeting of the American Academy of Neurology in 2012 showed that PET imaging with [18F] florbetaben detects beta-amyloid in the brains of living subjects. The visual assessment procedure proposed for routine clinical practice demonstrated 100% sensitivity and 92% specificity.

About Alzheimer's disease

Alzheimer's disease is a progressive neurodegenerative disease which primarily affects people over the age of 60 and is the most common cause of dementia. In 2009 estimates suggested that more than 36 million people worldwide were suffering from Alzheimer's. This figure could exceed 115 million by 2050. At present there is no cure for the disease, although treatments which may help with certain symptoms, combined with the right services and support, can improve the quality of life for the millions of people living with Alzheimer's.

About Piramal Enterprises Ltd.

Piramal Enterprises is one of India's largest diversified companies with operations in pharmaceuticals, financial services and information management. Piramal Enterprises generated consolidated revenues of $500 million in the 2012 financial year. In
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SOURCE Piramal Enterprises Ltd.
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