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Pipeline for Breast Cancer Therapies is Focus of New MedPredict Report
Date:8/27/2008

SCOTTSDALE, Ariz., Aug. 27 /PRNewswire/ -- MedPredict has published a new report in its oncology series entitled "Thought Leader Insight & Analysis: Breast Cancer," designed to provide critical strategic insight for pharma and biotech companies with a stake in the market for diagnostics and treatments in this disease area. MedPredict interviewed renowned North American and European breast cancer thought leaders to identify the most promising candidates in clinical development, as well as explore unmet needs. They address the following questions:

-- Has Novartis jumped ahead of Amgen in developing a breast cancer drug that provides a mortality benefit and preserves bone? MedPredict's panel debates the implications of Novartis' positive zoledronic acid (Zometa) data presented at ASCO 2008.

-- How prevalent is osteonecrosis of the jaw with antiresorptives, and how will this affect their usage in breast cancer?

-- How is triple negative breast cancer being treated, and where are the opportunities for development in this subtype?

-- What are the best approaches for development of inhibitors of mTOR, IGF1R, EGFR, PARP-1, HSP90, Src, angiogenesis, FA2, hedgehog, and vaccines?

"This report will provide essential strategic insight for those involved in development of breast cancer therapies," according to MedPredict President Dr. Jeffrey Berk. "Our report discusses ongoing clinical programs, and offers insight into which of the many new drugs in development are likely to be significant improvements over current options."

Companies included in this report: Abbott (ABT-888, ABT-999, A-928605), Abraxis/AstraZeneca (Abraxane), Amgen (denosumab, AMG-479), AstraZeneca (Arimidex, olaparib, saracatinib), Bayer-Schering (Bonefos), BiPar (BSI-201, BSI-401), Boehringer Ingelheim (Tovok), Bristol-Myers Squibb (brivanib, BMS-754807, Sprycel, Ixempra), BMS/Imclone (Erbitux), Exelixis (XL-765, XL-647), Genentech (Avastin, GDC-0941, Herceptin, pertuzumab, trastuzumab-DM1), GlaxoSmithKline (Tykerb), Imclone (IMC-A12, IMC-1121B), Kosan (tanespimycin), Merck (Fosamax, odanacatib, MK-0646), Myriad (BRCA1/BRCA2 Screening), Merck/Ariad (deforolimus), Novartis (Zometa, Femara, everolimus, patupilone, TAE-266), OSI (OSI-906), Pfizer (Aromasin, Sutent, Tarceva, CP-751871), Pierre Fabre (Javlor), Roche/GSK (Boniva), Roche (Xeloda), Sanofi-Aventis (AVE-1642), Schering-Plough (SCH-717454), and Wyeth (Torisel, neratinib).

The full report can be purchased by contacting MedPredict.

About MedPredict

MedPredict (http://www.medpredict.com) maintains a proprietary database of over 1,000 global physician thought leaders. Based on primary interviews with these thought leaders, MedPredict publishes periodic therapeutic area reports to keep clients up-to-date on emerging trends and competitive activity. The reports include thought leader reactions to recent publications and presentations, as well as clinical, regulatory and marketing activity.


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