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Photos: FDA Approves 12-Month Labeling Update for EVOLENCE(R) Collagen-Based Facial Filler
Date:6/8/2009

ther products do, but instead uses natural sugar to improve durability. EVOLENCE(R) collagen is cross-linked through its patented GLYMATRIX(TM) Technology using the natural sugar, D-Ribose. The GLYMATRIX(TM) process is designed to:

  • Mimic naturally occurring collagen in the skin by creating a true structural framework with natural, durable cross-links to ensure filler longevity
  • Provide consistent and predictable results
  • Use natural ingredients for natural-looking results

The naturally sourced porcine collagen used in EVOLENCE(R) is the most genetically similar to human collagen and has been used safely and effectively for decades in various medical applications, including heart valve replacement.

This new generation collagen filler is intended for injection into the mid-to-deep dermis for the correction of moderate to deep facial wrinkles and folds, such as nasolabial folds. The most common side effects of EVOLENCE(R) injections are usually injection-site related and include mild swelling, redness, and pain. Other rare side effects include the development of small areas of firmness under the skin at the treated sites that may be noticed when the areas are pressed upon.

EVOLENCE(R) has undergone rigorous testing and has been demonstrated to be safe and effective through clinical studies. For more information on the product, visit www.evolence.com.

(1) "Twelve-Month Persistency of a Novel Ribose-Cross-linked Collagen Dermal Filler," Narins, R. et. al., Dermatol Surg 2008; 34; S31-S39

* Initial treatment is defined as a single treatment with the option of touch-up within two to three weeks to achieve optimal correction.

About Ortho Dermatologics:

EVOLENCE(R) is marketed in the United States by Ortho Derm
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SOURCE Ortho Dermatologics
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