Navigation Links
Philanthropist John Moores Gives $2 Million to The Scripps Research Institute to Develop River Blindness Field Test
Date:3/20/2013

le in patients' urine, that is secreted by Onchocerca volvulus worms during an active infection.

"For this to be of value in Third World countries we need to morph this biomarker into something that's inexpensive, simple to use, tolerant of extreme temperatures and portable—basically distilling our finding to a test that can be carted around in a backpack," said Janda. "This new gift will make that possible."

A leading cause of vision loss, Onchocerciasis infections are transmitted among humans by river-dwelling blackflies in tropical regions. The vast majority of cases occur in sub-Saharan Africa, although pockets of endemic infection exist in Yemen and in Central and South America. The major symptoms of the disease, including blindness, result from the spread of O. volvulus "microfilariae"—early-stage larval worms—to the eyes and other tissues, where they trigger damaging inflammatory reactions.

Mass treatment campaigns, begun in the 1990s, have used the anti-worm drug ivermectin, as well as the antibiotic doxycycline, which kills a symbiotic bacterium within the worms. But Onchocerciasis treatment is seldom effective immediately, and often spares adult worms. The latter can remain in protected nodules under the skin of a patient and secrete microfilaria for a decade or more.

Current diagnostic methods include the painful cutting of "skin snips" from patients for microscopic analysis and an ELISA antibody test for microfilariae, which may yield positive results even for non-active infections. Health agencies need better diagnostic methods to track the progress of Onchocerciasis treatment campaigns and to wisely monitor the use of ivermectin and doxycycline to reduce the risk of resistance.

Janda envisions the new diagnostic test, which he hopes to develop over the next two years, as a simple, accurate and painless urine dipstick test, much like a home pregnan
'/>"/>

SOURCE The Scripps Research Institute
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3

Related biology technology :

1. Independent Marketing Automation Software Expert gives Positive review on MindMatrix's platform, AMP
2. New research gives insight into graphene grain boundaries
3. Tiny structure gives big boost to solar power
4. Artificial cornea gives the gift of vision
5. Rusterizer Brings Out New Non-Toxic Rust Remover, Gives Samples of the Product
6. Tropical Storm Debby Pounds Florida With Heavy Rain. Green Bean Buddy Gives Reason Why Home Owners Should Prepare For Mold Outbreaks
7. Tiger Woods Gives Exclusive First Interview Since POWERED by FUSE Announcement!
8. Nabsys Secures $20 Million Series D Financing to Support Launch of Semiconductor-Based Single-Molecule Platform for Genomic Analysis
9. Z Trim Holdings Announces Conclusion of Successful Warrant Exercise Program: Raises $2.195 Million
10. World Kidney Day Symposium at Allegheny General Hospital Brings Attention to Disease that Afflicts 26 Million People in U.S.
11. Aratana Closes $10 Million Non-Dilutive Financing with Square 1 Bank
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/22/2015)... January 22, 2015 Crystal Diagnostics (CDx) Xpress ... it has received AOAC-PTM Certifications for the six non-O157 Shiga ... O145; collectively referred to as STEC or the “Big-6”) as ... forming unit (cfu) per 325 g of raw ground beef ...
(Date:1/22/2015)... Boston, MA (PRWEB) January 22, 2015 ... systems, is pleased to announce an exciting product from a ... of motion analysis solutions over the past 15 years, with ... industries. Most recently, their 3D IMU system (inertial measurement unit), ...
(Date:1/22/2015)... 22, 2015 Controlled Substance Compliance Services ... helps companies check the legal requirements around using controlled ... China. , As their international operations expand and ... software solutions built as a result of the first ...
(Date:1/22/2015)... (PRWEB) January 22, 2015 Diagenode, ... such as the Bioruptor® and complete solutions for ... for chromatin immunoprecipitation, alleviating the need for manual ... controls needed for ChIP of histones or transcription ...
Breaking Biology Technology:Crystal Diagnostics Awarded AOAC-PTM Accreditation for the Rapid Detection of “Big 6” E.coli Food Pathogens 23D Motion Capture Just Got Easy 2Global Compliance Service for Controlled Substances to Expand to China 2Diagenode Launches Unique Semi-Automated Solution for Chromatin Immunoprecipitation 2
... that a new market research report is available in ... 2010 http://www.reportlinker.com/p0481350/China-Bio-breeding-Industry-Report-2010.html ... China reached RMB 29.8 billion, up 4.9% from a ... capable of R&D independently, but they seem inferior when ...
... University, the Salk Institute for Biological Studies, and other ... patient,s own brain cells, which then can be studied ... brings researchers a step closer to understanding the biological ... be used to study other mysterious diseases such as ...
... cooperative research center program (I/UCRC) will "provide a one-stop ... wide range of metamaterials." Dr. David Crouse, associate ... Engineering at The City College of New York, serves ... Participating institutions are The City University of ...
Cached Biology Technology:Reportlinker Adds China Bio-breeding Industry Report, 2010 2Reportlinker Adds China Bio-breeding Industry Report, 2010 3Reportlinker Adds China Bio-breeding Industry Report, 2010 4Reportlinker Adds China Bio-breeding Industry Report, 2010 5Scientists recreate brain cells from skin cells to study schizophrenia safely 2Scientists recreate brain cells from skin cells to study schizophrenia safely 3Grove School professor leads new metamaterials center 2Grove School professor leads new metamaterials center 3Grove School professor leads new metamaterials center 4
(Date:1/22/2015)... man-made form of insulin delivered by nasal spray may ... with mild cognitive impairment and Alzheimer,s disease dementia, according ... Forest Baptist Medical Center. The study,s subjects ... (MCI) or mild to moderate Alzheimer,s dementia (AD). Those ...
(Date:1/22/2015)... NEW YORK and POINT ROBERTS, Washington ... global news source covering leading sectors including technology and tech ... Personal Privacy marketplace featuring master pickpocket and security consultant ... wallet is stolen and talks about the Wocket™ biometric smart ...
(Date:1/22/2015)... , Europe,s most ... Patent Office to present a video retrospective of the most exciting ... Christofer Toumazou and Sophie Wilson   ... the Award   Starting on 22 January 2015 on   ...
Breaking Biology News(10 mins):Nasal Spray with Insulin Equivalent Shows Promise as Treatment for Adults with Mild Cognitive Impairment, Alzheimer's Dementia 2Nasal Spray with Insulin Equivalent Shows Promise as Treatment for Adults with Mild Cognitive Impairment, Alzheimer's Dementia 3Apollo Robbins Talks about the Illusion of Personal Safety and How Easily Your Wallet is Stolen; If a Wocket Wallet is Stolen the Thief Can't do Anything With it! 2Apollo Robbins Talks about the Illusion of Personal Safety and How Easily Your Wallet is Stolen; If a Wocket Wallet is Stolen the Thief Can't do Anything With it! 3Ten Years of the European Inventor Award: A Retrospective Look at the Inventors and Ideas That Have Changed Our Lives 2Ten Years of the European Inventor Award: A Retrospective Look at the Inventors and Ideas That Have Changed Our Lives 3
... 2009 A St. Louis-based team of plant and ... the developing world today announced the formation of ... involving St. Louis Children,s Hospital, The Donald Danforth ... Medicine. Though they share a commonality of ...
... 2009 - Temperature explains much of why cold-blooded ... longer at higher latitudes than at lower latitudes, according ... of the National Academy of Sciences ( PNAS ... candidate Santiago Salinas, both of Stony Brook University,s School ...
... STILLWATER, Okla. In a first to the ... Sciences and Natural Resources will receive $226,890 in grant ... Oklahoma Water Resources Research Institute. OWRRI and USGS ... encroachment and the water cycle in the tallgrass prairie, ...
Cached Biology News:Researchers team up to provide new hope for childhood hunger 2Researchers team up to provide new hope for childhood hunger 3Researchers team up to provide new hope for childhood hunger 4Warmer environment means shorter lives for cold-blooded animals 2Key OSU water research receives national funding 2
... Specificity: (4) ,human IgG subclass 1 100% ,human ... 100% ,human IgG subclass 4 ... 100% ,human IgG ... 0.04% ,human IgG Fab ...
...
Human VEGF R2 (KDR) MAb (Clone 89106)...
...
Biology Products: