Navigation Links
Pharmasset and Roche to Present R7128 Data at the 14th International Symposium on Hepatitis C Virus and Related Viruses


Rodriguez CA, Beard A, Symonds WT, Hill G and Berrey MM (Pharmasset,

Christchurch Clinical Studies Trust and Roche Palo Alto).

-- Abstract P-262: The Mechanism of Action of Beta-D-2'-Deoxy-2'-fluoro-

2'-C-methylcytidine Involves a Second Metabolic Pathway Leading to

Beta-D-2'-Deoxy-2'-fluoro-2'-C-methyluridine 5'-Triphosphate, a Potent

Inhibitor of the HCV RNA-Dependent RNA Polymerase. Murakami E, Niu C,

Bao H, Micolochick Steuer HM, Otto MJ and Furman PA (Pharmasset).

-- Abstract P-265: The Nucleoside Inhibitors R1479, PSI-6130, and NM107

have a Higher Genetic Barrier to Resistance than the Non-nucleoside

Inhibitor HCV-796 and the Protease Inhibitor VX-950. McCown M,

Rajyaguru S, Symons J, Cammack N and Najera I (Roche Palo Alto).

-- Abstract P-263: In Vitro Selection and Characterization of HCV

Replicons Resistant to PSI-6130. Ali S, Leveque V, LePogam S, Ma H,

Philipp F, Najera I, Klumpp K, Symons J, Cammack N and Jiang WR (Roche

Palo Alto).

-- Abstract P-259: Beta-D-2'-Deoxy-2'-fluoro-2'-C-methyluridine

Phosphoramidates: Potent and Selective Inhibitors of HCV RNA

Replication. Sofia MJ, Wang P, Du J, Micolochick Steuer HM, Niu C,

Furman PA and Otto MJ (Pharmasset).

About Pharmasset

Pharmasset is a clinical-stage pharmaceutical company committed to discovering, developing and commercializing novel drugs to treat viral infections. Pharmasset's primary focus is on the development of oral therapeutics for the treatment of hepatitis B virus (HBV), hepatitis C virus (HCV) and human immunodeficiency virus (HIV).

Pharmasset is currently developing three product candidates. Clevudine, for the treatment of chronic HBV infection, is expected to enter Phase 3 clinical trials for registration in the Americas and Europe. Clevudine is already approved for HBV in South Korea and marketed by

SOURCE Pharmasset, Inc.
Copyright©2007 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related biology technology :

1. Advantages of Roche Applied Science amplification products
2. Roche Diagnostics Corporation
3. Roche Diagnostics Corporation
4. NimbleGen to discontinue IPO after Roches $272.5 million acquisition
5. Prodesse enters patent agreement with Roche
6. Amplification of genome-representative DNA from limited sources with GenomePlex WGA technology for use in genetic alterations studies
7. Wisconsin firms to present at Cleantech venture capital event
8. New Sonic Foundry search engine finds words, phrases in video presentations
9. Lone Wisconsin firm to present at InvestMidwest
10. Sonic Foundry creates search engine for 7,000 expert video presentations
11. InvestMidWest calls for business presentations
Post Your Comments:
(Date:10/8/2015)... ... October 08, 2015 , ... Talon Innovations, a provider ... and other technology-driven industries, announces that it is one of three finalists for the ... Company.” On Thursday, September 25 Talon Innovations was recognized as a nominee for ...
(Date:10/7/2015)... , Oct. 7, 2015 Boston Scientific ... start of the Boston Scientific Connected Patient Challenge ... in the use of remote patient monitoring to enhance ... and entrepreneurs can submit their ideas and collaborate on ... ). Cambridge, MA ...
(Date:10/7/2015)...  ContraVir Pharmaceuticals, Inc. (Nasdaq: CTRV ) ("ContraVir" ... development and commercialization of targeted antiviral therapies, today announced ... shares of its common stock and warrants to purchase ... at a fixed combined price to the public of ... be issued separately.  The warrants will be exercisable for ...
(Date:10/7/2015)... 7, 2015   Intrexon Corporation (NYSE: ... it will hold an Investor Day in ... Thursday, November 12, 2015. Intrexon,s Chairman and Chief Executive ... of the Company,s management team as well as collaborators ... strategic initiatives, product pipeline, and program updates within its ...
Breaking Biology Technology:
... , ... integral to the SPEX FLUOROMAX -P or as an accessory ... information on various systems of chemical and biochemical interest, by revealing data ... <P,>This Application Note describes an example, using the SPEX ...
... , ... DataMax is the software used to display data from all SPEX ... a contour map. A contour map displays multifiles or 3-D data, and ... meteorological plot of barometric pressures. X values are plotted on the horizontal ...
... Introduction , ... 1 O 2 , is of considerable interest in environmental applications, ... been directed towards understanding the biological effects of 1 O 2 ... a dye, oxygen, and light. <P,>An understanding of the mechanisms that produce ...
Cached Biology Technology:
(Date:9/30/2015)... -- The global glucose monitoring device and diabetes management market is ... report on the industry from Kalorama Information. Sales in the traditional ... by continuous glucose monitoring and sensor segment, according to the ... products in its latest report, The Global Glucose Monitoring ... , ...
(Date:9/28/2015)... YORK , Sept. 28, 2015 /PRNewswire/ ... announced today that its expedited traveler service ... innovative platform transforms travel, bringing a frictionless ... its members. "CLEAR offers our ... enhances customer service," said Jim Smith ...
(Date:9/28/2015)... -- According to a new market research ... & Others), Application (Access Control & Others), Industry (Travel ... Global - Forecast to 2020", published by MarketsandMarkets, the Iris ... by 2020, at a CAGR of 23.40% between 2015 ... T ables and 66 Figures spread ...
Breaking Biology News(10 mins):
... that the dawn of agriculture may have come with ... some 11,400 years ago, roughly a thousand years before ... in the region. The discovery dates domesticated figs to ... making the fruit trees the oldest known domesticated crop. ...
... combining the four bacterial surface proteins that generate ... the University of Chicago have created a vaccine ... drug-resistant strains of Staphylococcus aureus, the most common ... source of community-associated illness. , The vaccine ...
... June 15th issue of G&D, Dr. Marie-Louise Hammarskjold (UVA) ... the Wilms' Tumor 1 tumor suppressor. The Wilms' Tumor ... pathological human development, with known roles in kidney and ... , Dr. Hammarskjold and colleagues reveal that WT1 works ...
Cached Biology News:
... a silica based spin filter membrane to isolate ... DNA band is cut from an agarose gel ... The gel slice is melted irreversibly in a ... bound to the silica spin filter membrane and ...
... incorporation of Br-dUTP results in a stronger ... a fluorescein-labeled anti-BrdU antibody. Propidium iodide/RNase ... to counterstain the total DNA. Features and ... improved detection than found by using biotin- ...
Mouse polyclonal antibody raised against a partial recombinant WRB. NCBI Entrez Gene ID = 7485...
Biology Products: