Navigation Links
PharmAthene Presents Data for Valortim(R) Anthrax Anti-Toxin and Third Generation rPA Anthrax Vaccine Programs at the Bacillus - ACT 2009 Conference
Date:9/3/2009

gram was developed to accelerate the commercialization of technology in Maryland by jointly funding collaborative R&D projects between companies and University System of Maryland faculty.

Separately, Dr. Louise Pitt, Director, Center for Aerobiological Sciences, U.S. Army Medical Research Institute of Infectious Diseases (USAMRIID), presented data in a poster entitled, "Therapeutic Efficacy of Valortim((R)) an Anti-toxin Monoclonal Antibody, in the African Green Monkey Model of Inhalational Anthrax." Inhalational anthrax in certain primates such as African Green Monkeys (AGMs) is believed to follow a similar disease course as in humans.

In this randomized, blinded study, 48 AGMs were exposed by aerosol to Ames anthrax spores and blood samples were collected every 8 hours, beginning 24 hours post-exposure, to assess antigenemia (protective antigen 'PA' in circulation) and bacteremia. Samples were assayed for PA by a rapid electrochemiluminescence immunoassay (ECL), and bacteremia was confirmed by culture. The presence of PA in the blood of infected animals was the trigger for initiation of treatment with normal saline control, or Valortim((R)) at doses of 5, 10, 20 or 40 mg/kg.

In the study, AGMs were exposed by aerosol to Ames spores (approximately 200 LD(50)). Up to seventy percent (70%) of the Valortim((R))-treated animals survived. All AGMs were bacteremic at the time of treatment. These data suggest that Valortim((R) )may be a promising therapy for inhalational anthrax in symptomatic individuals and may have utility for use as rescue therapy.

The therapeutic efficacy study of Valortim((R)), given as a monotherapy in the AGM model, is being conducted by PharmAthene and its collaborators at USAMRIID, and has been funded in whole or in part with Federal funds from the Department of Defense through the United States Army Medical Research Institute of Infectious Di
'/>"/>

SOURCE PharmAthene, Inc.
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7 8 9

Related biology technology :

1. Hearing Scheduled in the Delaware Court of Chancery for August 27, 2007 to Establish the Valid Approval and Consummation of the Merger Between PharmAthene, Inc. and Healthcare Acquisition Corp.
2. Proceedings to Affirm Merger Between PharmAthene and Healthcare Acquisition Corp Initiated in Delaware Chancery Court
3. PharmAthene Named as Contractor in $13.9 Million Award Notice Published by the Department of Health and Human Services
4. Delaware Court Denies Motion by SIGA Technologies Seeking to Dismiss PharmAthenes Legal Action in Breach of Contract Lawsuit Against SIGA
5. PharmAthene to Present at the BIO CEO & Investor Conference 2008
6. PharmAthene Enhances Executive Leadership Team and Appoints Joan Fusco, Ph.D. Senior Vice President of Operations
7. PharmAthene Completes Pharmacokinetic Studies of Protexia(R); Program on Target for IND Filing in 2008
8. PharmAthene to Present at the Cowen and Company 28th Annual Health Care Conference
9. PharmAthene Signs Definitive Agreement to Acquire Biodefense Vaccines Business From Avecia
10. PharmAthene to Delay Release of Full Year 2007 Financial Results
11. PharmAthene Year-End 2007 Earnings Conference Call and Webcast Scheduled for Monday, March 31, 2008
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/15/2014)... The Microcompetition with Foreign DNA theory explains how latent ... viruses is the Epstein Barr Virus (EBV), and one of ... a chronic inflammatory disease that destroys the body’s joints. As ... have high concentrations of EBV DNA in their bodies (1). ...
(Date:1/15/2014)... AudioNotch is the internet's leading provider ... treatment of tinnitus. Patients listen to sound therapy that ... period of weeks to months, their tinnitus volume decreases. , ... Notched Music and Notched White Noise. Now, AudioNotch is pleased ...
(Date:1/14/2014)... January 14, 2014 Histogen, Inc., a ... of cells grown under simulated embryonic conditions, today announced ... with Suneva Medical, Inc. for physician-dispensed aesthetic products containing ... , This agreement is an amendment to the existing ...
(Date:1/14/2014)... , Jan. 14, 2014 The largest international ... medicinal plants and therapeutic derivatives thereof has endorsed ... and researchers about the challenges of adulterated herb ... ) The Society for Medicinal ...
Breaking Biology Technology:Study: Rheumatoid Arthritis (RA) Patients Have EBV; The CBCD Says this is Consistent with Microcompetition 2Study: Rheumatoid Arthritis (RA) Patients Have EBV; The CBCD Says this is Consistent with Microcompetition 3Histogen and Suneva Medical Expand License for Cell Conditioned Media-based Aesthetic Products Internationally 2Histogen and Suneva Medical Expand License for Cell Conditioned Media-based Aesthetic Products Internationally 3World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 2World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 3World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 4World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 5World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 6World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 7World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 8
... Va. The American Institute of Aeronautics and ... of top emerging aerospace technologies. Developed by ... the following: 1. "Greener Aviation" Technologies including ... in the Federal Aviation Administration,s Continuous Low Emissions, ...
... Multifaceted agreement enhances Microsoft Amalga Life Sciences to accelerate ... REDMOND, Wash., June 1 Microsoft Corp. today announced ... Co. Inc. to acquire certain assets of Rosetta Biosoftware, ... owned subsidiary of Merck & Co. Inc. The deal ...
... ... for Mass Spectrometry-based biomarker discovery will be demonstrated at the 57th ASMS Conference on ... Center. , ... PA (PRWEB) June 1, 2009 -- Genedata , a leading provider of in ...
Cached Biology Technology:AIAA names top ten emerging aerospace technologies of 2009 2Microsoft Signs Agreement With Merck & Co. Inc. to Acquire Assets of Rosetta Biosoftware, Strengthening Position in Life Sciences Industry 2Microsoft Signs Agreement With Merck & Co. Inc. to Acquire Assets of Rosetta Biosoftware, Strengthening Position in Life Sciences Industry 3Genedata Launches Expressionist with Expanded Mass Spectrometry Biomarker Discovery Capabilities 2Genedata Launches Expressionist with Expanded Mass Spectrometry Biomarker Discovery Capabilities 3
(Date:4/23/2014)... Wash. -- Like a hungry diner ripping open a ... into electricity must tear open a hydrogen molecule. Now ... holding onto the two halves of its hydrogen feast. ... how to make the catalyst work better for alternative ... scientists have shown precisely where the hydrogen halves end ...
(Date:4/23/2014)... have conclusive evidence that the source of a unique ... and called the "bio-duck," is the Antarctic minke whale ... submarine personnel in the 1960s who thought it sounded ... at various locations in the Southern Ocean, but its ... February 2013, an international team of researchers deployed acoustic ...
(Date:4/23/2014)... At a signing ceremony in Buenos Aires yesterday, ... as an associate member state. The move strengthens ... life science communities. It grants Argentinian scientists access ... mutually beneficial collaborations. , "Ever since its inception, ... internationalisation have been at the core of EMBL,s ...
Breaking Biology News(10 mins):Halving hydrogen 2Halving hydrogen 3Halving hydrogen 4Scientists identify source of mysterious sound in the Southern Ocean 2Scientists identify source of mysterious sound in the Southern Ocean 3
... Sure, some delicacies might taste just like chicken, but they ... as the soy burger, have become more popular recently, with ... scientists at the University of Missouri have created a soy ... The new soy chicken also has health benefits, including lowering ...
... Researchers at the University of Pittsburgh and their ... to pursue the continued development of an implanted ventricular ... congenital or acquired heart disease. The project aims to ... saved the lives of older heart failure patients. ...
... scientists are reporting the first discovery of the female ... thought that only animals could make progesterone. A steroid ... for pregnancy and maintains pregnancy. A synthetic version, progestin, ... The discovery is reported in the American Chemical ...
Cached Biology News:It looks, feels and tastes like chicken, but it's made of soy 2Pitt-led team gets $5.6 million contract for heart assist device for infants and toddlers 2Pitt-led team gets $5.6 million contract for heart assist device for infants and toddlers 3