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PharmAthene Presents Data for Valortim(R) Anthrax Anti-Toxin and Third Generation rPA Anthrax Vaccine Programs at the Bacillus - ACT 2009 Conference
Date:9/3/2009

ANNAPOLIS, Md., Sept. 3 /PRNewswire-FirstCall/ -- PharmAthene, Inc. (NYSE Amex: PIP), a biodefense company developing medical countermeasures against biological and chemical threats, announced today that data from the Company's third generation recombinant protective antigen (rPA) anthrax vaccine program and its Valortim((R)) anthrax anti-toxin program were presented at the Bacillus - ACT 2009 meeting, August 30 - September 3, 2009, organized by the American Society for Microbiology.

David P. Wright, President and Chief Executive Officer of PharmAthene commented, "Preliminary data from our third generation (3G) rPA anthrax vaccine program suggest that a 3G product prototype may be able to provide a more rapid onset of immunity and enhanced immunogenicity than the currently available anthrax vaccine, suggesting the potential for a vaccine that can be given in fewer doses than is required today."

"Additionally, new data from our Valortim((R)) program were presented highlighting the potential for Valortim((R)) as a promising new therapeutic for anthrax. In the African Green Monkey (AGM) model, up to 70% of Valortim((R))-treated animals survived inhalational challenge with anthrax spores. A second poster, presented additional studies in immunodeficient mouse models, and demonstrated the unique activity of Valortim((R)) in protecting these mice from being killed by B. anthracis. These data suggest a potential unique mechanism of action for Valortim(TM) that will need to be substantiated in additional studies," continued Mr. Wright.

Valortim((R)), which is being co-developed by PharmAthene and Medarex, Inc., is a fully human monoclonal antibody designed to protect against and treat inhalational anthrax, the most lethal form of illness in humans caused by
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