Navigation Links
People fall into 3 categories of gut microbiota
Date:4/21/2011

"The three gut types can explain why the uptake of medicines and nutrients varies from person to person," says bioinformatician Jeroen Raes of the VIB and Vrije Universiteit Brussel, one of the two lead researchers in the study. "This knowledge could form the basis of personalized therapies. Treatments and doses could be determined on the basis of the gut type of the patient."

Improved knowledge of the gut types could also lead to other medical applications, such as the early diagnosis of intestinal cancer, Crohn's disease and the adverse effects of obesity.

Three types of gut microbiota

The types of gut microbiota (called enterotypes) can be classified into three large, clearly distinguishable groups: Bacteroides, Prevotella and Ruminococcus. They are named for the bacteria that dominate the intestines of the respective groups. It is still unclear whether people can change from one group to another during their lives.

Bacteria form strong ecosystem in the gut

Scientists do not yet have a conclusive explanation for the existence of the types of gut microbiota, but all the evidence indicates that only a limited number of stable biotic communities are possible in our intestines. In this way they are comparable to other ecosystems in nature, such as forests, tundra, tropical jungles, savannas and others. Ecosystems have a tendency to evolve towards a stable equilibrium, with certain species that become dominant and others that occupy niches. This also appears to apply to our intestines.

Relationship with BMI

The study shows a connection between human characteristics and gut microbiota. For instance, correlations were found between the Body Mass Index (BMI) and the strains of bacteria in the gut. The more efficiently the bacteria can extract energy from the food, the greater the chance that the person has a high BMI (and therefore struggles with obesity). The researchers found that the presence of certain bacterial genes could serve as diagnostic and/or predictive markers for obesity. This finding is currently undergoing further testing in a clinical study in a group of over 100 individuals. This involves examining the DNA of the complete gut microbiome of those.

Differences in vitamin production

It is notable that the vitamin production between the different groups varies strongly. People that belong to the Bacteroides group have more gut bacteria that produce vitamins C, B2, B5 and H. The Prevotella group showed higher numbers of B1 and folic acid-producing flora.

Crucial role of gut microbiota

An estimated 100,000 billion individual bacteria live in our intestines. They form our gut microbiota. These bacteria play a crucial role in protecting our health. They help to covert food into energy and protect us against attacks by pathogens. In exchange for these benefits, our bodies provide the bacteria with habitat and nutrition.

Metagenomics as a study method

In the past, the study of gut microflora was very difficult. The problem was that most gut bacteria cannot be cultivated in a lab and only survive in the intestines. A different approach is now used. Instead of cultivating the bacteria, the genetic information (DNA) of all the bacteria is studied together (metagenomics). This generates a vast amount of data that is analyzed using powerful computers.


'/>"/>

Contact: Jeroen Raes
jeroen.raes@vib-vub.be
32-477-697-668
VIB (the Flanders Institute for Biotechnology)
Source:Eurekalert

Related biology technology :

1. LF Elimination Program Treats Over Half Billion People and Protects Millions More From Debilitating Disease
2. MyHeritage And Family Tree DNA Partner To Help People Trace Family History Using DNA
3. Health Robotics Announces Partnership in the Peoples Republic of China With The Devon International Group
4. Video: Experts Unite to Help People Manage Spring Nasal Allergy Sneezin
5. Niusule Biotech Corp. Formally Establishes a New Venture to Import and Sell Health Foods in the Peoples Republic of China
6. Kendle Senior Scientist Edward Sellers, MD, PhD, Named One of Nine Notable People in R&D
7. MEDS World, LLC Provides Multiple Environments with Designed Solutions - Wherever People Congregate, MEDS Odor Elimination Solutions Offer Eco-Friendly, Odor-Free Air
8. Patton Medical Devices Partners With Unomedical to Develop and Market the i-port Advance(TM) Injection Port for People Taking Multiple Daily Injections
9. Video: New Way RA(TM) Talk Show Premieres Online for People Living With Rheumatoid Arthritis (RA)
10. Fast Forward, LLC and Amplimmune, Inc. Join Forces to Speed New Treatments to People with MS**
11. New Vision Device Passes Virtual Collision Test for People with Tunnel Vision
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/23/2017)... Research and Markets has announced the addition of the ... ... The Global Market for Bioproducts Should Reach $714.6 Billion by ... 8.9%, This research report quantifies the two ... segments: bio-derived chemicals, biofuels, pharmaceuticals (biodrugs and herbal/botanicals), biocomposite materials, ...
(Date:3/23/2017)... Mass. , March 23, 2017 /PRNewswire/ ... partner to global in vitro diagnostics manufacturers ... of the industry,s first multiplexed Inherited ... disease testing by next-generation sequencing (NGS). The ... were developed with input from industry experts ...
(Date:3/23/2017)... PARK, Calif., March 23, 2017  BioPharmX Corporation ... products for the dermatology market, today reported financial ... 31, 2017, and will provide an update on ... the year. "We are pleased to ... year for BioPharmX," said President Anja Krammer. "We ...
(Date:3/23/2017)... -- Kineta, Inc., a biotechnology company focused on ... today announced the discovery and characterization of several ... interferon response factor 3 (IRF3) via RIG-I like ... in a murine colon carcinoma mouse model.  Furthermore, ... regression to initial drug treatment were resistant to ...
Breaking Biology Technology:
(Date:2/21/2017)... 2017 Der weltweite Biobanking-Sektor wird ... einem Gespräch mit mehr als 50 Vertretern aus verschiedenen Branchen ... gilt, um diese Prognose zu realisieren. ... Zu den ... finanziellen Mittel für die Biobank, die Implementierung Zeit sparender ...
(Date:2/13/2017)... FRANCISCO , Feb. 13, 2017  RSA ... centralized platform that is designed to enhance fraud ... latest release in the RSA Fraud & Risk ... enable organizations to leverage additional insights from internal ... tools to better protect their customers from targeted ...
(Date:2/9/2017)... 2017 The biomass boiler market report by ... boiler market globally in terms of revenue (US$ Mn) ... market for biomass boilers has been segmented on the ... country/region. The market based on feedstock type, has been ... & energy crops, urban residues, and others. On the ...
Breaking Biology News(10 mins):