Navigation Links
People fall into 3 categories of gut microbiota

"The three gut types can explain why the uptake of medicines and nutrients varies from person to person," says bioinformatician Jeroen Raes of the VIB and Vrije Universiteit Brussel, one of the two lead researchers in the study. "This knowledge could form the basis of personalized therapies. Treatments and doses could be determined on the basis of the gut type of the patient."

Improved knowledge of the gut types could also lead to other medical applications, such as the early diagnosis of intestinal cancer, Crohn's disease and the adverse effects of obesity.

Three types of gut microbiota

The types of gut microbiota (called enterotypes) can be classified into three large, clearly distinguishable groups: Bacteroides, Prevotella and Ruminococcus. They are named for the bacteria that dominate the intestines of the respective groups. It is still unclear whether people can change from one group to another during their lives.

Bacteria form strong ecosystem in the gut

Scientists do not yet have a conclusive explanation for the existence of the types of gut microbiota, but all the evidence indicates that only a limited number of stable biotic communities are possible in our intestines. In this way they are comparable to other ecosystems in nature, such as forests, tundra, tropical jungles, savannas and others. Ecosystems have a tendency to evolve towards a stable equilibrium, with certain species that become dominant and others that occupy niches. This also appears to apply to our intestines.

Relationship with BMI

The study shows a connection between human characteristics and gut microbiota. For instance, correlations were found between the Body Mass Index (BMI) and the strains of bacteria in the gut. The more efficiently the bacteria can extract energy from the food, the greater the chance that the person has a high BMI (and therefore struggles with obesity). The researchers found that the presence of certain bacterial genes could serve as diagnostic and/or predictive markers for obesity. This finding is currently undergoing further testing in a clinical study in a group of over 100 individuals. This involves examining the DNA of the complete gut microbiome of those.

Differences in vitamin production

It is notable that the vitamin production between the different groups varies strongly. People that belong to the Bacteroides group have more gut bacteria that produce vitamins C, B2, B5 and H. The Prevotella group showed higher numbers of B1 and folic acid-producing flora.

Crucial role of gut microbiota

An estimated 100,000 billion individual bacteria live in our intestines. They form our gut microbiota. These bacteria play a crucial role in protecting our health. They help to covert food into energy and protect us against attacks by pathogens. In exchange for these benefits, our bodies provide the bacteria with habitat and nutrition.

Metagenomics as a study method

In the past, the study of gut microflora was very difficult. The problem was that most gut bacteria cannot be cultivated in a lab and only survive in the intestines. A different approach is now used. Instead of cultivating the bacteria, the genetic information (DNA) of all the bacteria is studied together (metagenomics). This generates a vast amount of data that is analyzed using powerful computers.


Contact: Jeroen Raes
VIB (the Flanders Institute for Biotechnology)

Related biology technology :

1. LF Elimination Program Treats Over Half Billion People and Protects Millions More From Debilitating Disease
2. MyHeritage And Family Tree DNA Partner To Help People Trace Family History Using DNA
3. Health Robotics Announces Partnership in the Peoples Republic of China With The Devon International Group
4. Video: Experts Unite to Help People Manage Spring Nasal Allergy Sneezin
5. Niusule Biotech Corp. Formally Establishes a New Venture to Import and Sell Health Foods in the Peoples Republic of China
6. Kendle Senior Scientist Edward Sellers, MD, PhD, Named One of Nine Notable People in R&D
7. MEDS World, LLC Provides Multiple Environments with Designed Solutions - Wherever People Congregate, MEDS Odor Elimination Solutions Offer Eco-Friendly, Odor-Free Air
8. Patton Medical Devices Partners With Unomedical to Develop and Market the i-port Advance(TM) Injection Port for People Taking Multiple Daily Injections
9. Video: New Way RA(TM) Talk Show Premieres Online for People Living With Rheumatoid Arthritis (RA)
10. Fast Forward, LLC and Amplimmune, Inc. Join Forces to Speed New Treatments to People with MS**
11. New Vision Device Passes Virtual Collision Test for People with Tunnel Vision
Post Your Comments:
(Date:6/23/2016)... ... 2016 , ... Charm Sciences, Inc. is pleased to announce ... Research Institute approval 061601. , “This is another AOAC-RI approval of the Peel ... President of Regulatory and Industrial Affairs. “The Peel Plate methods perform comparably to ...
(Date:6/23/2016)... FRANCISCO , June 23, 2016   EpiBiome ... has secured $1 million in debt financing from Silicon ... ramp up automation and to advance its drug development ... its new facility. "SVB has been an ... beyond the services a traditional bank would provide," said ...
(Date:6/23/2016)... ... , ... In a new case report published today in STEM CELLS Translational ... lymphedema after being treated for breast cancer benefitted from an injection of stem cells ... this debilitating, frequent side effect of cancer treatment. , Lymphedema refers to ...
(Date:6/23/2016)... Andrew D Zelenetz ... Published recently in Oncology ... touchONCOLOGY, Andrew D Zelenetz , discusses the ... is placing an increasing burden on healthcare systems ... With the patents on many biologics expiring, interest ...
Breaking Biology Technology:
(Date:6/3/2016)... 2016 Das DOTM ... Nepal hat ein 44 Millionen ... Kennzeichen, einschließlich Personalisierung, Registrierung und IT-Infrastruktur, an ... und Implementierung von Identitätsmanagementlösungen. Zahlreiche renommierte internationale ... teilgenommen, aber Decatur wurde als konformste und ...
(Date:6/1/2016)... , June 1, 2016 ... in Election Administration and Criminal Identification to Boost Global ... a recently released TechSci Research report, " Global Biometrics ... Region, Competition Forecast and Opportunities, 2011 - 2021", the ... billion by 2021, on account of growing security concerns ...
(Date:5/12/2016)... -- , a brand of Troubadour Research ... the Q1 wave of its quarterly wearables survey. A ... to a program where they would receive discounts for ... "We were surprised to see that so ... , CEO of Troubadour Research, "primarily because there are ...
Breaking Biology News(10 mins):