Navigation Links
Palatin Technologies, Inc. Issued U.S. Patent for Heart Failure Drug Candidate
Date:12/1/2009

CRANBURY, N.J., Dec. 1 /PRNewswire-FirstCall/ -- Palatin Technologies, Inc. (NYSE Amex: PTN) today announced that the U.S. Patent and Trademark Office has issued U.S. Patent No. 7,622,440, titled "Cyclic Natriuretic Peptide Constructs." The claims in the issued patent cover a family of cyclic compounds that bind to natriuretic peptide receptor A (NPRA), including PL-3994, Palatin's lead heart failure drug candidate.

"Our natriuretic compounds, including PL-3994, address significant unmet medical needs," said Trevor Hallam, Ph.D., Palatin's Executive Vice President - Research and Development. "These are the only reported compounds that bind to NPRA and have extended half-lives and pharmacokinetic properties making daily subcutaneous administration possible. Besides the potential to decrease re-hospitalization rates in patients with heart failure, PL-3994 may also have application in treating resistant hypertension and pulmonary arterial hypertension."

PL-3994 and the related family of cyclic compounds were discovered and developed by Palatin scientists and are solely owned by Palatin. In addition to this issued U.S. patent, Palatin has applications pending in selected countries outside the United States and additional U.S. applications covering related compounds.

About PL-3994

Palatin has completed two clinical trials with PL-3994, a Phase 1 trial in healthy volunteers and a Phase 2a trial in patients with controlled hypertension. PL-3994 produced dose-related decreases in blood pressure, increases in plasma cGMP (cyclic guanosine monophosphate), a natural messenger nucleotide, and increases in urine volume and sodium excretion. There were no serious or severe adverse events.

PL-3994 incorporates a novel and proprietary amino acid mimetic developed by scientists at Palatin
'/>"/>

SOURCE Palatin Technologies, Inc.
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3

Related biology technology :

1. Palatin Technologies, Inc. Reports First Quarter Fiscal Year 2010 Results; Teleconference and Webcast to be held on November 16, 2009
2. Palatin Technologies, Inc. Reports Fourth Quarter and Fiscal Year End 2009 Results; Teleconference and Webcast to be held on September 8, 2009
3. Palatin Technologies, Inc. to Report Fourth Quarter and Fiscal Year 2009 Results; Teleconference and Webcast to be held on September 8, 2009
4. Palatin Technologies to Present at the Rodman & Renshaw 11th Annual Global Investment Conference
5. Palatin Technologies, Inc. to Raise $3.1 Million in Registered Direct Offering
6. Palatin Technologies, Inc. Reports Positive Bremelanotide Study; Improved Safety Profile with Subcutaneous Administration
7. Palatin Technologies, Inc. Receives U.S. Patent Allowance for Heart Failure Drug Candidate
8. Palatin Technologies Listing Compliance Plan Accepted by NYSE Alternext US
9. Palatin Technologies to Report Fiscal Year 2009 Second Quarter Results; Conference Call and Webcast on February 17, 2009
10. Palatin Technologies Receives Notification Letter from NYSE Alternext US
11. Palatin Technologies to Report Fiscal Year 2009 First Quarter Results; Conference Call and Webcast on November 17, 2008
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/23/2014)... York , September 23, 2014 ... leading provider of  Closed System Transfer     Devices ... exclusive partnership with Taiwanese distributor MedFront Medical Technology Corporation.  Equashield,s ... in Taiwan , ... as the company continues to expand globally, and ...
(Date:9/23/2014)... 23, 2014 Dr. Williams says, “Find ... on healthcare offers a three phase process that can ... delivery system that would go far beyond anything previously ... the delivery of healthcare.” , “Every effort to improve ... to provide discernable progress throughout that system because all ...
(Date:9/23/2014)... England , September 23, 2014 ... launched with funding from Imperial Innovations, Cambridge Innovation Capital ... Inivata, a clinical cancer genomics company focused on ... analysis to improve cancer testing and treatment, today ... round led by Imperial Innovations and including Cambridge ...
(Date:9/22/2014)... and SANTA CLARA, Calif. , Sept. ... WBMD ), the leading source of health information, ... survey that provide novel insights regarding physician and ... and care.  Dr. Eric Topol , a leading ... who serves as both Editor-in-Chief of Medscape and Chief ...
Breaking Biology Technology:Equashield Enters Taiwan Following Expansion to Australia, Japan, China 2Dr. Ira Williams Offers the Healthcare Solution Necessary for Patient Safety Improvement 2Inivata Raises £4m to Realise the Potential of ctDNA Analysis to Improve Cancer Treatment Through Simple Blood Tests 2Inivata Raises £4m to Realise the Potential of ctDNA Analysis to Improve Cancer Treatment Through Simple Blood Tests 3Inivata Raises £4m to Realise the Potential of ctDNA Analysis to Improve Cancer Treatment Through Simple Blood Tests 4WebMD/Medscape Digital Technology Survey Reveals Unique Insights Into How Patients and Physicians Perceive the Role, Potential and Risks Associated with Digital Health Technologies 2WebMD/Medscape Digital Technology Survey Reveals Unique Insights Into How Patients and Physicians Perceive the Role, Potential and Risks Associated with Digital Health Technologies 3WebMD/Medscape Digital Technology Survey Reveals Unique Insights Into How Patients and Physicians Perceive the Role, Potential and Risks Associated with Digital Health Technologies 4
... Bowl MVP,s; 94 NFL First Round Draft Picks; ... ... BASKING RIDGE, N.J., Feb. 8 Millennium,Biotechnologies Inc., wholly-owned subsidiary ... SURGEX(TM) is,currently being administered as the exclusive post workout nutritional,product provided ...
... Calif., Feb. 8 Genomic Health,Inc. (Nasdaq: GHDX ... Chief Operations Officer, will present at the BIO CEO ... 2008 at 10:15 a.m. Eastern,Time., To access the ... Investor Relations section of Genomic Health,s,website at http://investor.genomichealth.com ...
... available in Spanish . , ANN ARBOR, ... from walking to operate a portable GPS locator, a ... neurotransmitter, research involving the University of Michigan shows. , ... Feb. 8 issue of the journal Science. Authors include ...
Cached Biology Technology:Tom Shaw's NFL Training Center Chooses SURGEX(TM) as Their Exclusive Post Training Nutritional Regimen 2Tom Shaw's NFL Training Center Chooses SURGEX(TM) as Their Exclusive Post Training Nutritional Regimen 3Knee brace generates electricity from walking 2
(Date:9/23/2014)... Rice University scientists who are fighting a cyberwar against ... clinician,s most powerful ally. , "Recent research has found ... the immune system, and we studied the interplay between ... might turn the tables on cancer," said Rice University,s ... in the Early Edition of the Proceedings of ...
(Date:9/23/2014)... the washing up, negotiating rights to the TV remote control ... university for the new academic year are about to learn ... business. , And now research from academics at The University ... to monitor their energy usage in the home could be ... a team of technology experts and psychologists found that meters ...
(Date:9/23/2014)... 2014 Research and Markets  has announced ... and Opportunities, 2019" report to their offering. ... enhancing security and protection in private as well as ... country,s government is focusing on using biometric systems to ... national IDs that are of crucial importance to the ...
Breaking Biology News(10 mins):Immune system is key ally in cyberwar against cancer 2Immune system is key ally in cyberwar against cancer 3Smart meters could cause conflict for housemates, study shows 2Smart meters could cause conflict for housemates, study shows 3India Biometrics Market Forecast and Opportunities, 2019 2India Biometrics Market Forecast and Opportunities, 2019 3
... Military, homeland security, law enforcement and other first-responder ... to attend the 2009 Force Protection Equipment Demonstration ... 600 exhibits will be presented at Stafford County ... Quantico, VA. Live-fire small arms and explosives survivability ...
... Technology (Caltech) and the University of California at San ... Caltech experimental data to show just how amino-acid chains ... Their insights were recently published in the February 10 ... of Sciences (PNAS). The paper details the ...
... human genome eight years ago, enormous progress has been ... of most human genes is still barely understood. An ... gene or protein is to compare its sequence with ... experimentally easier to investigate. From the functions of related ...
Cached Biology News:Demonstration Targets Terrorism 2Caltech and UCSD researchers shed light on how proteins find their shapes 2Relationships in rank and file 2Relationships in rank and file 3Relationships in rank and file 4
... service provides the premium quality siRNAs you ... siRNAs can be readily ordered online by ... or by providing the sense and antisense ... Silencer Validated and Silencer ...
... custom siRNA service provides the premium quality ... research. Custom siRNAs can be readily ordered ... target sequence, or by providing the sense ... Ambion's Silencer Validated and ...
dithiothreitol, sulfhydryl reducing agent, C4H10O2S2; MW: 154.24, 97% pure (minimum), CAS No: 27565-41-9, store at -20 C ...
... NAP-10 Columns, 50. For rapid and ... 10-mers) in less than 15 minutes by ... in distilled water containing 0.15% Kathon CG/ICP ... volume: 0.5 ml (NAP-5), 1 ml ...
Biology Products: