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PacificGMP and USC to Collaborate on Recombinant Protein Development and Manufacturing for Phase 1 Clinical Trial
Date:7/27/2009

l need for treatments for DEB and, since the work is primarily funded by non-profit sources, their willingness to perform the clinical manufacturing in a significantly cost-effective manner," said David Woodley, M.D., founding chair of the Department of Dermatology at the Keck School of Medicine and Director of the Residency Training Program in Dermatology. "Skin in children with DEB lacks anchoring fibrils that normally connect the epidermal layer of the skin to the dermis causing the skin's layers to separate, blister and slough off at the slightest insult or injury. There are currently only palliative treatments for DEB, so it is exciting to establish this partnership with a CMO that is able to quickly initiate drug manufacturing for the clinical trial."

About PacificGMP

PacificGMP is a contract manufacturer and industry leader in single-use technology for development and manufacturing of biologics. Single-use technology eliminates the risk of cross-contamination, has fewer system requirements and significantly reduces the time required to initiate production. Benefits to clients include rapid project turnaround and the most cost effective solution in the industry. PacificGMP partners with drug developers by providing a range of cGMP and non-GMP services from cell line optimization, cell banking, early process design, development, purification and scale-up, to preclinical and clinical manufacturing, aseptic filling, testing, analytical services and regulatory support. More information can be found by visiting the Company's Web site at www.PacificGMP.com.

About Keck School of Medicine of USC

The Keck School of Medicine of University of Southern California is among the nation's leaders for innovative clinical care, research and education of future physicians. Located on the university's 30.8-acre Health Sciences C
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