at all, the risk
that Soliris will not generate interest among physicians, the risk that
estimates regarding the number of PNH patients are inaccurate, the risk
that pending litigation may be resolved adversely, and a variety of other
risks set forth from time to time in Alexion's filings with the Securities
and Exchange Commission, including but not limited to the risks discussed
in Alexion's Quarterly Report on Form 10-Q for the period ended June 30,
2007 and in our other filings with the Securities and Exchange Commission.
Alexion does not intend to update any of these forward-looking statements
to reflect events or circumstances after the date hereof, except when a
duty arises under law.
(1) Rother R, Bell L, Hillmen P, Gladwin M. The clinical sequelae of
intravascular hemolysis and extracellular plasma hemoglobin. JAMA
(2) Parker C, Omine M, Richards S, et al. Diagnosis and management of
paroxysmal nocturnal hemoglobinuria. Blood 2005; 106:3699-3709.
(3) Socie G, Mary J Yves, de Gramont A, et al. Paroxysmal nocturnal
haemoglobinuria: long-term follow-up and prognostic factors. Lancet
(4) Hillmen P. Lewis SM, Bessler M, Luzzatto L, Dacie JV. Natural history
of paroxysmal nocturnal hemoglobinuria. N Engl J Med 1995;
(5) Moyo VM, Mukhina GL, Garrett ES, Brodsky RA. Natural history of
paroxysmal nocturnal haemoglobinuria using modern diagnostic assays.
Br J Haematol. 2004;126:133-138.
(6) Araten DJ, Thaler HT, Luzzatto L. High incidence of thrombosis in
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