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Oxford BioMedica Announces Update from ARVO 2013
Date:5/9/2013

ctor® gene delivery technology

Oxford BioMedica's LentiVector® gene delivery technology is one of the most advanced gene delivery systems currently available, which has many applications in product development and discovery research.  It is the system of choice for gene-based treatments addressing chronic and inherited diseases.  Oxford BioMedica has established a dominant intellectual property estate in the field of lentiviral-vector mediated gene delivery through its in-house research and from work conducted by the Company's co-founders at Oxford University.

4. Usher syndrome type 1B and UshStat®

Usher syndrome is the most common form of deaf-blindness which affects approximately 30,000-50,000 patients in the US and Europe.  One of the most common subtypes is Usher syndrome type 1B. The disease is caused by a mutation of the gene encoding myosin VIIA (MY07A), which leads to progressive retinitis pigmentosa combined with a congenital hearing defect.  UshStat® uses the Company's LentiVector® platform technology to deliver a corrected version of the MYO7A gene to address the vision loss associated with the disease.  On the basis of pre-clinical data, it is anticipated that a single application of UshStat® to the retina could provide long-term or potentially permanent stabilisation of vision.  There are currently no approved treatments available for Usher syndrome type 1B.

For further information, please contact:

Oxford BioMedica plc:
Lara Mott , Head of Corporate Communications
Tel: +44(0)1865-783-000

Casey Eye Institute:
Mirabai Vogt
Tel: +1-503-494-7986

Media Enquiries:
Mary Clark / Sarah Macleo
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SOURCE Oxford BioMedica plc
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