Navigation Links
Ortho Biotech Statement On JAMA Publication Regarding Erythropoiesis-Stimulating Agents
Date:2/26/2008

be titrated for each patient to achieve and

maintain the following hemoglobin levels:

* Chronic renal failure patients -- hemoglobin levels between 10 to 12

g/dL. If a patient does not attain hemoglobin levels of 10 to 12

g/dL despite 12 weeks of appropriate PROCRIT therapy, see DOSAGE and

ADMINISTRATION in the PROCRIT Prescribing Information.

* Cancer or HIV patients -- the lowest hemoglobin level sufficient to

avoid transfusion and not to exceed 12 g/dL.

-- Monitor hemoglobin regularly during therapy, more frequently following

a dosage adjustment or until hemoglobin becomes stable.

-- Cases of pure red cell aplasia (PRCA) and of severe anemia, with or

without other cytopenias, associated with neutralizing antibodies to

erythropoietin have been reported in patients with chronic renal

failure receiving PROCRIT by subcutaneous administration. If any

patient develops a sudden loss of response to PROCRIT, accompanied by

severe anemia and low reticulocyte count, and anti-erythropoietin

antibody-associated anemia is suspected, withhold PROCRIT and other

erythropoietic proteins. Contact ORTHO BIOTECH (1-888-2ASKOBI or

1-888-227-5624) to perform assays for binding and neutralizing

antibodies. If erythropoietin antibody-mediated anemia is confirmed,

PROCRIT should be permanently discontinued and patients should not be

switched to other erythropoietic proteins.

-- The safety and efficacy of PROCRIT therapy have not been established in

patients with a known history of a seizure disorder or underlying

hematologic disease (e.g., sickle cell anemia, myelodysplastic

syndromes or hypercoagulable disorders).

-- In some female patients, menses have resumed following PROCRIT therapy;

the possibility of pregnancy should be discussed and the
'/>"/>

SOURCE Ortho Biotech
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6

Related biology technology :

1. Ortho Biotech Supports FDA Advisory Committees Recommendations on Use of ESAs in Chronic Renal Failure Patients
2. Isis Enters Broad Collaboration With Ortho-McNeil, Inc. for the Discovery, Development and Commercialization of Antisense Drugs to Treat Metabolic Diseases
3. New Orthopedic Surgical Robotics Company Opens Its Doors; Files with the FDA for Clearance of Its Flagship Product
4. Innovative Neurotronics, a Subsidiary of Hanger Orthopedic Group, Earns the 2007 da Vinci Award for the WalkAide System
5. Bone-growing nanomaterial could improve orthopaedic implants
6. Advancements in Population Age and Technology Drive Future of Orthopedic Materials Market
7. Collagen Matrix, Inc. Launches OssiMend(TM) Bone Graft Matrix for Orthopedic and Spine Applications
8. Ortho Biotech Modifies Prescribing Information for PROCRIT(R) (Epoetin alfa) Label Reflects Recommendations from Recent FDA Advisory Committee Meetings
9. Progentix Orthobiology B.V. Closes Series A Financing Round
10. Barr and Ortho Womens Health & Urology in Discussions to Settle ORTHO TRI-CYCLEN(R) LO Patent Litigation
11. Kensey Nash to Present at the Canaccord Adams Small-Cap Orthopedics Conference
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/23/2014)... SKOKIE, Ill. , July 23, 2014 ... acid (SNA™) constructs as gene regulatory and ... Snyder has joined AuraSense Therapeutics, executive ... July 11. Prior to joining ... President and Chief Financial Officer of Cellular ...
(Date:7/23/2014)... StemGenex® , the leading resource ... aimed at improving the lives of patients dealing with ... Parkinson’s disease. StemGenex believes that a commitment to ... paramount when providing care to patients with degenerative diseases. ... therapy accessible to the millions of individuals currently living ...
(Date:7/23/2014)... 2014 Shire plc (LSE: ... specialty biopharmaceutical company, and ArmaGen, a US privately ... and collaboration agreement for AGT-182, an investigational enzyme ... both the central nervous system (CNS) and somatic ... This collaboration strengthens Shire,s rare disease pipeline of ...
(Date:7/23/2014)... N.J. (PRWEB) July 23, 2014 ... Comprehensive Cancer Center has joined its Strategic Alliance ... Strategic Alliance Partnership program, UNC Lineberger will have ... to raise awareness of its cutting-edge research initiatives, ... from UNC Lineberger will work with OncLive to ...
Breaking Biology Technology:AuraSense Therapeutics Appoints Biotechnology Veteran David S. Snyder as Chief Financial Officer 2StemGenex® Gives Hope to Parkinson’s Patients through New Stem Cell Clinical Study 2StemGenex® Gives Hope to Parkinson’s Patients through New Stem Cell Clinical Study 3Shire Enters Strategic Licensing and Collaboration Agreement With ArmaGen 2Shire Enters Strategic Licensing and Collaboration Agreement With ArmaGen 3Shire Enters Strategic Licensing and Collaboration Agreement With ArmaGen 4Shire Enters Strategic Licensing and Collaboration Agreement With ArmaGen 5OncLive Expands Its Strategic Alliance Partnership Program With the Addition of UNC Lineberger Comprehensive Cancer Center 2OncLive Expands Its Strategic Alliance Partnership Program With the Addition of UNC Lineberger Comprehensive Cancer Center 3
... on just about anything: Post-Its, a text file on my laptop, ... ,Recently, I've started trying out a free online service, Ta-Da ... track of to-do items. It was made by 37 Signals ... is why they can offer it free without any advertising. , ...
... career, Bob Weisenberg read a lot of books on management ... the way through yet another book, he realized he had ... in the software industry, Weisenberg says the way to excel ... limited number of skills, not by reading more books about ...
... you like your job (or maybe you're not wild about it) ... that keeps you glued to your desk. , ,It could also ... weather's warmer or after the Cubs opener or some other milestone. ... more of these 10 signs may tell you that your Midwest ...
Cached Biology Technology:Ta-Da Lists makes it fun to check things off 2Northwoods Software co-owner distills 30 years of business experience 2Northwoods Software co-owner distills 30 years of business experience 3Northwoods Software co-owner distills 30 years of business experience 4Ten signs tell you to look for a new tech job 2Ten signs tell you to look for a new tech job 3Ten signs tell you to look for a new tech job 4
(Date:7/23/2014)... by satellite over a 15-year period off the U.S. ... feed in specific locations each year, according to a ... PLOS ONE by Ladd Irvine from Oregon ... to mitigate human threats to the whale population. , ... recover since the establishment of protections in the mid-1960s. ...
(Date:7/23/2014)... tissue samples cultured from cystic fibrosis patients, scientists at ... Lung Institute have shown that a new CF drug ... drug. , The finding, published today in the journal ... CFTR protein becomes unstable and loses its ability to ... drugs. The research offers several insights into how novel ...
(Date:7/23/2014)... , , , , , ... , , , , , ... chronic diseases and extend healthy lifespan. The idea, they argue, would be to target the... , , ... , , , , , ... , , , , , , , , ...
Breaking Biology News(10 mins):Blue whales' dangerous feeding grounds 2UNC researchers find unsuspected characteristics of new CF drugs, offering potential paths to more effective therapies 2UNC researchers find unsuspected characteristics of new CF drugs, offering potential paths to more effective therapies 3UNC researchers find unsuspected characteristics of new CF drugs, offering potential paths to more effective therapies 4Strategy proposed for preventing diseases of aging 2Strategy proposed for preventing diseases of aging 3Strategy proposed for preventing diseases of aging 4Strategy proposed for preventing diseases of aging 5
... in German . The Deutsche Forschungsgemeinschaft ... new Research Units. This decision was taken by the DFG,s ... the research consortia is to offer researchers the opportunity to ... to establish innovative research directions. As with all ...
... Sandia,s decontamination foam, developed more than a decade ago ... during the 2001 anthrax attacks, is now being used ... chemical engineer in Sandia,s Chemical & Biological Systems Dept. ... renders all types of typical chemical and biological agents ...
... Ganges River ,and Irrawaddy dolphins declared by the ... study ,with Bangladesh Forest Department helped pinpoint location ... The Government of Bangladesh recently declared three new ... world,s largest mangrove ecosystem the Sundarbans, according ...
Cached Biology News:DFG to establish 4 new research units 2DFG to establish 4 new research units 3Anthrax-killing foam proves effective in meth lab cleanup 2Anthrax-killing foam proves effective in meth lab cleanup 3Anthrax-killing foam proves effective in meth lab cleanup 4New protected areas for dolphins declared 2New protected areas for dolphins declared 3
Umbilical cord blood CD4+ T cells, For immunohistochemistry (IHC) Cell Chip with Human Umbilical Cord Blood MNCs and T Cells...
Human endothelial progenitor cells, For immunohistochemistry (IHC) Cell Chip with Human Peripheral Blood Dendritic Cells and EPCs...
Human monocyte-derived dendritic cells, For immunohistochemistry (IHC) Cell Chip with Human Peripheral Blood Dendritic Cells and EPCs...
...
Biology Products: