Navigation Links
Ortho Biotech Statement On JAMA Publication Regarding Erythropoiesis-Stimulating Agents

ed for transfusion in anemic patients who are scheduled for elective noncardiac, nonvascular surgery. Depending on the country in which Epoetin alfa is marketed, these indications may differ.

Important U.S. Safety Information for PROCRIT


Renal failure: Patients experienced greater risks for death and serious cardiovascular events when administered erythropoiesis-stimulating agents (ESAs) to target higher versus lower hemoglobin levels (13.5 vs. 11.3 g/dL; 14 vs. 10 g/dL) in two clinical studies. Individualize dosing to achieve and maintain hemoglobin levels within the range of 10 to 12 g/dL.


-- ESAs shortened overall survival and/or time-to-tumor progression in

clinical studies in patients with advanced breast, head and neck,

lymphoid, and non-small cell lung malignancies when dosed to target a

hemoglobin of greater than or equal to 12 g/dL.

-- The risks of shortened survival and tumor progression have not been

excluded when ESAs are dosed to target a hemoglobin of < 12 g/dL.

-- To minimize these risks, as well as the risk of serious cardio -- and

thrombovascular events, use the lowest dose needed to avoid red blood

cell transfusions.

-- Use only for treatment of anemia due to concomitant myelosuppressive


-- Discontinue following the completion of a chemotherapy course.

Perisurgery: PROCRIT increased the rate of deep venous thromboses in patients not receiving prophylactic anticoagulation. Consider deep venous thrombosis prophylaxis.


PROCRIT is contraindicated in patients with uncontrolled hypertension or with known hypersensitivity to albumin (human) or mammalian cell-derived products.

Additional Important Safety Information

-- The dose of PROCRIT should

SOURCE Ortho Biotech
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6

Related biology technology :

1. Ortho Biotech Supports FDA Advisory Committees Recommendations on Use of ESAs in Chronic Renal Failure Patients
2. Isis Enters Broad Collaboration With Ortho-McNeil, Inc. for the Discovery, Development and Commercialization of Antisense Drugs to Treat Metabolic Diseases
3. New Orthopedic Surgical Robotics Company Opens Its Doors; Files with the FDA for Clearance of Its Flagship Product
4. Innovative Neurotronics, a Subsidiary of Hanger Orthopedic Group, Earns the 2007 da Vinci Award for the WalkAide System
5. Bone-growing nanomaterial could improve orthopaedic implants
6. Advancements in Population Age and Technology Drive Future of Orthopedic Materials Market
7. Collagen Matrix, Inc. Launches OssiMend(TM) Bone Graft Matrix for Orthopedic and Spine Applications
8. Ortho Biotech Modifies Prescribing Information for PROCRIT(R) (Epoetin alfa) Label Reflects Recommendations from Recent FDA Advisory Committee Meetings
9. Progentix Orthobiology B.V. Closes Series A Financing Round
10. Barr and Ortho Womens Health & Urology in Discussions to Settle ORTHO TRI-CYCLEN(R) LO Patent Litigation
11. Kensey Nash to Present at the Canaccord Adams Small-Cap Orthopedics Conference
Post Your Comments:
(Date:7/29/2014)... (PRWEB) July 29, 2014 The first ... a next generation approach to robotics. What sets Droidles ... patent pending technology that allows them to communicate, share ... wirelessly over the internet. , “The invention is the ... the little Droidles a life of their own, both ...
(Date:7/29/2014)... 2014 EXpressLO LLC, expert provider of ... preparation solutions, has been granted patent number 8,789,826 by ... methods incorporating a unique specimen carrier support grid design ... second company patent for EXpressLO LLC awarded to founder ... These complementary patents extend EXpressLO’s portfolio of intellectual property. ...
(Date:7/28/2014)... 2014 “2014 Deep Research ... is a professional and in-depth research report ... report introduces Lubricant basic information, including Lubricant ... and industry overview. This research covers the ... as well as global industry analysis covering ...
(Date:7/28/2014)... July 28, 2014 ... Identification Market by Products (Consumables, Instruments, Services), Methods (Phenotypic, ... User (Detection, Characterization) - Global Forecasts to ... Market is estimated at $896.5 Million in ... Million by 2019, growing at a CAGR ...
Breaking Biology Technology:Droidles, the Social Network of Robots and Open Source Platform for the Internet of Things, Launches for Crowd Funding on 2EXpressLO LLC Granted Second U.S. Patent for Innovative Specimen Preparation Methods 2Lubricant Market & Adhesion Promoter Industry (Globa, China) Analysis Now Available at 2Lubricant Market & Adhesion Promoter Industry (Globa, China) Analysis Now Available at 3Lubricant Market & Adhesion Promoter Industry (Globa, China) Analysis Now Available at 4Microbial Identification Market worth $1,194.1 Million by 2019 2Microbial Identification Market worth $1,194.1 Million by 2019 3
... Cell Therapeutics, Inc.,(CTI) (Nasdaq and MTAX: CTIC) ... (the "Letter") from Nasdaq indicating that the Company,s,recently ... Preferred,Stock (the "Series C Preferred") and warrants did ... Nasdaq Marketplace Rule 4351 and IM 4351.,The Nasdaq ...
... Plan Extends Financial Resources Beyond 2008 -, ... Inc. (Nasdaq: SNSS ) today announced that ... and implementing a revised,operating plan that focuses its ... while streamlining the company,s operations and extending,its financial ...
... for Early and Accurate Diagnosis of Peripheral Artery ... Disease ... - Findings Published Online in Circulation -, FREMONT, Calif., Aug. 28 ... research that details how a protein biomarker called beta-2,microglobulin may aid in the ...
Cached Biology Technology:Cell Therapeutics, Inc. Takes Corrective Actions in Response to Nasdaq Determination 2Sunesis Pharmaceuticals Announces Reorganization to Focus Resources and Build Value in Clinical-Stage Programs 2Sunesis Pharmaceuticals Announces Reorganization to Focus Resources and Build Value in Clinical-Stage Programs 3Sunesis Pharmaceuticals Announces Reorganization to Focus Resources and Build Value in Clinical-Stage Programs 4Vermillion and Collaborators Discover Protein Biomarker Associated with Peripheral Artery Disease 2Vermillion and Collaborators Discover Protein Biomarker Associated with Peripheral Artery Disease 3
(Date:7/29/2014)...  When it comes to technology, healthcare is usually one of ... However, when it comes to wearables, healthcare is trying to move ... Internet of Things and its wearable cousins is less than mature, ... industry, whether it,s in the hospital for a major procedure or ... With that in mind, InformationWeek editor Rodney Brown ...
(Date:7/29/2014)... of Kent has shown for the first time how ... that could have a major impact on cancer therapy ... uncovered the mechanism whereby the physical properties of the ... are ,fine-tuned, to undertake different functions. , While ... providing a framework for the cell, others are more ...
(Date:7/29/2014)... for parents of preterm babies latest research from the ... they become teenagers, the brains of many preterm children can ... A study conducted by the University,s Robinson Research Institute ... experiences no brain injury in early life, their cognitive abilities ... term-born peers. , However, the results of the study, published ...
Breaking Biology News(10 mins):Preterm children's brains can catch up years later 2
... involved in cellular immune signaling, scientists have succeeded in making ... protein with a new twist may eventually be used to ... involved in immune responses that are initiated by proteins called ... the immune system in response to challenges by foreign agents ...
... properties of human bone has been made by scientists ... scientists describe their results –?finding a sort of "glue" ... August issue of the international scientific journal, Nature Materials. ... It describes how healthy bone resists fracture and how ...
... Georgia Institute of Technology and the John Innes Centre ... which disease-causing bacteria may thwart the body's natural defense ... development of more effective antibiotics, appear in the September ... oxide is produced by the body to fight infections. ...
Cached Biology News:Engineered molecule amplifies body's immune response 2Engineered molecule amplifies body's immune response 3Fundamental discovery -- Bone fracture 2Fundamental discovery -- Bone fracture 3Researchers uncover E. coli's defense mechanism 2
Purified anti-DNA-PKcs Phosphorylated (Thr2609)...
Purified anti-PI3K p110 delta...
Biotin anti-mouse Ly-49C/F/I/H...
... Purified Tyrosine Hydroxylase (Ser40) Polyclonal ... raised against synthetic phosphopeptide corresponding ... the phospho-Ser40 of rat Tyrosine ... purified by sequential chromatography on ...
Biology Products: