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Orexigen Therapeutics Announces Multiple Data Presentations at The Obesity Society Annual Scientific Meeting
Date:9/29/2008

nter: Sonja K. Billes, Ph.D.

Title: "Leptin Regulates Food Intake Via Dopamine Receptor-Dependent

Mechanisms"

Time: 11:30-11:45 a.m. MT

Poster Presentation

Abstract: 847-P

Title: "Quality of Life Improvements from a Dose Optimization Study with

Zonisamide SR and Bupropion SR"

Time: 12:45-2:45 p.m. MT

Poster Presentation

Abstract: 848-P

Title: "Timing of Response from a Dose Optimization Study with Zonisamide

SR and Bupropion SR"

Time: 12:45-2:45 p.m. MT

Upcoming Corporate Presentations

JMP Securities Healthcare Sector Focus Conference

Le Parker Meridien, New York

October 6, 2008

10:00 a.m. ET

BIOCOM Investor Conference

Hyatt Regency La Jolla, San Diego

October 28, 2008

4:00 p.m. PT

About Orexigen Therapeutics

Orexigen Therapeutics, Inc. is a biopharmaceutical company focused on the development of pharmaceutical product candidates for the treatment of central nervous system disorders, including obesity. The Company's lead combination product candidates targeted for obesity are Contrave(R), which is in Phase 3 clinical trials, and Empatic(TM), which is in late-stage of Phase 2 clinical development. Each product candidate is designed to act on a specific group of neurons in the central nervous system with the goal of achieving appetite suppression and sustained weight loss. Beyond obesity, Orexigen is developing drug combinations for use in schizophrenia and obsessive-compulsive disorder. Further information about the company can be found at http://www.Orexigen.com.


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SOURCE Orexigen Therapeutics, Inc.
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