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Orexigen Therapeutics Announces Multiple Data Presentations at The Obesity Society Annual Scientific Meeting
Date:9/29/2008

-- Company Also Announces Participation in Upcoming Investor Conferences in

October --

SAN DIEGO, Sept 29 /PRNewswire-FirstCall/ -- Orexigen Therapeutics, Inc. (Nasdaq: OREX), a biopharmaceutical company focused on the treatment of obesity and other central nervous system-related disorders, today announced its active calendar of events for October 2008, which includes six data presentations and one sponsored symposium at The Obesity Society Annual Scientific Meeting, as well as upcoming corporate presentations at noteworthy investor conferences.

The Obesity Society Annual Scientific Meeting, Phoenix Convention Center

Saturday, October 4

Poster Presentation

Abstract: 317-P

Title: "The Naltrexone-Bupropion Combination Reduces the Prevalence of the

Metabolic Syndrome and Improves Cardiometabolic Markers in At-Risk

Subjects"

Time: 5:00-7:00 p.m. MT

Sunday, October 5

Symposium

Event Code: E1280

Title: "Reward and Obesity; Too Much of a Good Thing?"

Time: 6:15-7:45 a.m. MT

Location: Hyatt Regency Phoenix, Regency Ballroom A/B

Oral Presentation

Abstract: 61-OR

Presenter: Ronald Landbloom, M.D.

Title: "Long Term Weight Loss from a Dose Optimization Study with

Zonisamide SR and Bupropion SR"

Time: 11:00-11:15 a.m. MT

Poster Presentation

Abstract: 585-P

Title: "Relative Bioavailability of Sustained-release (SR) versus

Immediate-release (IR) Naltrexone (NAL) Formulations in Healthy Obese

Volunteers: Implications for Improved Tolerability?"

Time: 5:30-7:30 p.m. MT

Monday, October 6

Oral Presentation

Abstract: 104-OR

Presenter: Sonja K. Billes, Ph.D.

Title: "Leptin Regulates Food Intake Via Dopamine Receptor-Dependent

Mechanisms"

Time: 11:30-11:45 a.m. MT

Poster Presentation

Abstract: 847-P

Title: "Quality of Life Improvements from a Dose Optimization Study with

Zonisamide SR and Bupropion SR"

Time: 12:45-2:45 p.m. MT

Poster Presentation

Abstract: 848-P

Title: "Timing of Response from a Dose Optimization Study with Zonisamide

SR and Bupropion SR"

Time: 12:45-2:45 p.m. MT

Upcoming Corporate Presentations

JMP Securities Healthcare Sector Focus Conference

Le Parker Meridien, New York

October 6, 2008

10:00 a.m. ET

BIOCOM Investor Conference

Hyatt Regency La Jolla, San Diego

October 28, 2008

4:00 p.m. PT

About Orexigen Therapeutics

Orexigen Therapeutics, Inc. is a biopharmaceutical company focused on the development of pharmaceutical product candidates for the treatment of central nervous system disorders, including obesity. The Company's lead combination product candidates targeted for obesity are Contrave(R), which is in Phase 3 clinical trials, and Empatic(TM), which is in late-stage of Phase 2 clinical development. Each product candidate is designed to act on a specific group of neurons in the central nervous system with the goal of achieving appetite suppression and sustained weight loss. Beyond obesity, Orexigen is developing drug combinations for use in schizophrenia and obsessive-compulsive disorder. Further information about the company can be found at http://www.Orexigen.com.


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SOURCE Orexigen Therapeutics, Inc.
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