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Orexigen(R) Therapeutics to Present at Upcoming Meetings
Date:5/13/2009

SAN DIEGO, May 13 /PRNewswire-FirstCall/ -- Orexigen(R) Therapeutics, Inc. (Nasdaq: OREX), a biopharmaceutical company focused on the treatment of obesity, today announced that the Company will be speaking at the following meetings:

    BIO 2009 Business Forum
    Date:  Tuesday, May 19, 2009
    Time:  9:20 a.m. - 9:35 a.m. Eastern
    Location:  Georgia World Congress Center, Room 316, Atlanta, Georgia
    Speaker:  Dr. Dennis Kim, Senior Vice President, Medical Affairs and
              Communications

    Eighth Annual JMP Securities Research Conference
    Date:  Tuesday, May 19, 2009
    Time:  9:00 a.m. - 9:30 a.m. Pacific
    Location:  The Ritz Carlton, San Francisco
    Speaker:  Graham Cooper, Chief Financial Officer

About Orexigen Therapeutics

Orexigen Therapeutics, Inc. is a biopharmaceutical company focused on the treatment of obesity. The Company's lead combination product candidates targeted for obesity are Contrave(R), which is in Phase 3 clinical trials, and Empatic(TM), which is in the later stages of Phase 2 clinical development. Each product candidate is designed to act on a specific group of neurons in the central nervous system with the goal of achieving appetite suppression and sustained weight loss. Further information about the Company can be found at http://www.orexigen.com.


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5. Orexigen(R) Therapeutics Schedules March 12, 2009 Webcast Discussion of Financial Results for the Fourth Quarter and Year Ended December 31, 2008
6. Orexigen(R) Therapeutics to Speak at BIO CEO & Investor Conference
7. Orexigen(R) Therapeutics Announces First of Four Phase 3 Trials of Contrave(R) Meets Co-Primary and Key Secondary Endpoints
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11. Orexigen(R) Therapeutics Appoints Dennis Kim, M.D., as Senior Vice President, Head of Obesity and Metabolic Disorders
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