Navigation Links
Optimization and Scale-up of a Hydrodynamically Limited Anti-Solvent Crystallization Process: From Lab to Plant
Date:8/13/2009

This two part Optimization and Scale-up of a Hydrodynamically Limited Anti-Solvent Crystallization Process: From Lab to Plant webinar series is based on an award winning paper presented at the 16th International Process Development Conference. The webinar series focuses on a semi-quantitative method for the optimization and scale-up of hydrodynamically limited antisolvent crystallization process. This protocol combines in situ Process Analytical Technologies (PAT) with Computational Fluid Dynamics (CFD) to facilitate the production of a knowledge based scale-up strategy for this mixing limited crystallization process.

Columbia, MD (PRWEB) August 13, 2009 -- Part 1 of the Optimization and Scale-up of a Hydrodynamically Limited Anti-Solvent Crystallization Process webinar series takes place on September 24 and presents this optimization protocol. Certain attributes of turbulent mixing have been identified to greatly impact key crystallization characteristics, such as the metastable zone width (MSZW), primary and secondary nucleation events, growth and agglomeration rates. This section focuses on the use of Process Analytical Technology (PAT) and Computational Fluid Dynamics (CFD) in understanding these common industrial crystallization challenges and in turn facilitates the production of methods for the scale-up and scale-down of this process.

Part 2 of the Optimization and Scale-up of a Hydrodynamically Limited Anti-Solvent Crystallization Process webinar series, on October 1, takes the developed protocol to a scale-down and scale-up environment and demonstrates how crystal nucleation, growth and dimension can be maintained on scale. This approach highlights the necessity for a link to be forged between crystal size, form, kinetics, etc. and the attained mixed environment. In turn, a platform is produced to facilitate the right first time crystallization scale-up, tech transfers and scale-down assessments of this hydrodynamically limited process.

The webinar presenter, Mark Barrett, received his Ph.D. from University College Dublin (UCD) in Ireland, where he also studied Chemical Engineering. His thesis work focused on crystallization development and scale-up. Previously, Mark worked for Schering-Plough as a Process Development Engineer. Mark is now a Senior Research and Development Engineer at the Solid State Pharmaceutical Cluster (SSPC), based in Ireland.

###

Read the full story at http://www.prweb.com/releases/crystallization/PAT/prweb2740064.htm.


'/>"/>
Source: PRWeb
Copyright©2009 Vocus, Inc.
All rights reserved  

Related biology technology :

1. Seambiotic USA and NASA Glenn Research Center Signed Agreement for Large Scale Microalgae Process Optimization
2. DNA2.0 Awarded US Patents for Breakthrough Gene Optimization Technology -- Company's Unique Algorithm Enables Expression Yields up to 50 Times Greater than Competing Approaches
3. ETS Laboratories Offers New Process Optimization Tools to the Fuel Ethanol Industry
4. U.S. Hospital Sales Opportunities Maximized Through Functional Optimization
5. Caliper Life Sciences and DiscoveRx Collaborate to Offer Solutions for Cell-Based GPCR Profiling and Lead Optimization
6. Genencor Launches Accellerase(R) 1500, Next Step Toward Scale-Up of Cellulosic Ethanol
7. ThalesNano Flow Reactor Realizes Microwave Speed With Scale-up Ability
8. DuPont Applied BioSciences Selects MBI to Collaborate on Process Development and Scale-Up for New Bio-based Product
9. ProMetic announces scale-up of prion removal resin in plasma product for biopharmaceutical use
10. Celtic Pharma Holdings Announces Investment in Novacta Biosystems Limited
11. CSL Limited and Talecris Biotherapeutics Agree to Terminate Merger Agreement
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Optimization and Scale-up of a Hydrodynamically Limited Anti-Solvent Crystallization Process: From Lab to Plant
(Date:6/24/2016)... June 24, 2016 Epic Sciences unveiled ... cancers susceptible to PARP inhibitors by targeting homologous ... (CTCs). The new test has already been incorporated ... multiple cancer types. Over 230 clinical ... response pathways, including PARP, ATM, ATR, DNA-PK and ...
(Date:6/23/2016)... June 23, 2016   Boston Biomedical , ... compounds designed to target cancer stemness pathways, announced ... granted Orphan Drug Designation from the U.S. Food ... gastric cancer, including gastroesophageal junction (GEJ) cancer. Napabucasin ... to inhibit cancer stemness pathways by targeting STAT3, ...
(Date:6/23/2016)...  The Prostate Cancer Foundation (PCF) is pleased to announce 24 ... for prostate cancer. Members of the Class of 2016 were selected from a ... Read More About the Class of 2016 PCF Young Investigators ... ... ...
(Date:6/23/2016)... ... ... In a new case report published today in STEM CELLS Translational Medicine, doctors ... being treated for breast cancer benefitted from an injection of stem cells derived from ... frequent side effect of cancer treatment. , Lymphedema refers to the swelling ...
Breaking Biology Technology:
(Date:6/21/2016)... VANCOUVER, British Columbia , June 21, 2016 ... been appointed to the new role of principal ... has been named the director of customer development. ... , NuData,s chief technical officer. The moves reflect ... development teams in response to high customer demand ...
(Date:6/9/2016)... , June 9, 2016 ... Police deploy Teleste,s video security solution to ensure the safety ... France during the major tournament Teleste, ... communications systems and services, announced today that its video security ... to back up public safety across the country. ...
(Date:6/2/2016)... , June 2, 2016 Perimeter ... Platforms, Unmanned Systems, Physical Infrastructure, Support & Other Service  ... visiongain offers comprehensive analysis of the global ... market will generate revenues of $17.98 billion in 2016. ... DVTEL Inc, a leader in software and hardware technologies ...
Breaking Biology News(10 mins):