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Onyx Pharmaceuticals Names N. Anthony Coles, M.D. as President, Chief Executive Officer and Member of its Board of Directors
Date:2/26/2008

EMERYVILLE, Calif., Feb. 26 /PRNewswire-FirstCall/ -- Onyx Pharmaceuticals, Inc. (Nasdaq: ONXX) today announced that it has appointed N. Anthony Coles, M.D., president, chief executive officer and a member of the company's board of directors, effective March 31, 2008. Dr. Coles succeeds Hollings C. Renton, who announced his retirement plans last October. Mr. Renton is retiring as president, chief executive officer, chairman and member of the Onyx Board of Directors on the same date.

"Tony is the ideal person to lead Onyx as we build on the success of Nexavar," said Mr. Renton, president, chief executive officer, and chairman of Onyx. "He is a proven leader with a track record of success in building commercial teams and working with corporate collaborators to maximize product opportunities. His extensive executive and operations-based background will be a major contributor to driving value for Onyx, and we are delighted that he will be joining the company."

"It is an honor and a privilege to be joining Onyx at this exciting time in the company's history," said Dr. Coles. "I believe the Nexavar franchise holds tremendous commercial growth potential and further clinical promise. Together with Onyx's talented employees and strong partner, Bayer, we intend to bring the unique benefits of Nexavar to cancer patients around the globe. Through this and other initiatives, we look forward to achieving our goals and building sustainable long-term value for stockholders."

"The members of the Onyx board welcome Tony and thank Hollings for his dedicated leadership over the last 15 years," said Wendell Wierenga, Ph.D., a member of the Onyx board and chairman of the nominating and governance committee. "During Hollings' tenure, Nexava
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SOURCE Onyx Pharmaceuticals, Inc.
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