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Ontario Institute for Cancer Research Announces Spin Off Companies Developing Promising Anticancer Technologies
Date:5/19/2011

Toronto General Research Institute. Named Double Negative T-cells (DNT cells), these extremely rare cells have been shown in animal testing to kill leukemia cells and have undergone extensive pre-clinical testing. By utilizing the patient's own DNT cells the risk of rejection or an adverse reaction is minimized. Funds from OICR will be used to prepare the technology for a first-in-human clinical trial which is expected to commence in early 2012.

  • DLVR Therapeutics Inc., Developing a Nanoparticle Delivery System for Anticancer Therapies

DLVR Therapeutics Inc., a company created by OICR and the University Health Network, is developing a novel nanocarrier delivery and targeting technology that may enable the delivery of toxic chemotherapeutics and siRNA to cancer cells more safely and with greater therapeutic impact.  The DLVR technology – which is nontoxic, biocompatible and biodegradable -- has the potential to reduce side effects for cancer patients.

Invented in the laboratory of Dr. Gang Zheng of the University Health Network in Toronto, proof of concept has been demonstrated in animal models of cancer. Additional development will be performed with proceeds from OICR's investment to accelerate development of the new nanocarrier for the treatment of cancer.

  • Harmonic Medical, Inc. Developing a Patented Ultrasound Therapy

Harmonic Medical is perfecting a novel tumour treatment system, invented by scientists at Sunnybrook Health Sciences Centre and Brigham and Women's Hospital, led by Kullervo Hynynen. Harmonic Medical uses ultrasound to precisely target and destroy cancer sites deep within the body. Novel harmonic imaging is used to provide feedback to ensure that tumours are destroyed while sparing healthy tissue. Proceeds from OICR's investment will be used to complete prototype validation and prepare
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SOURCE Ontario Institute for Cancer Research
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