Navigation Links
Ontario Institute for Cancer Research Announces Investment in Microfluidics Technology for the Discovery of Anti-Cancer Drugs
Date:3/24/2011

TORONTO, March 24, 2011 /PRNewswire/ -- The Ontario Institute for Cancer Research (OICR) announced today it has made an investment to accelerate commercialization of a potentially revolutionary high-throughput screening technology directed at the discovery of anticancer drugs. The technology, Smart Well Plate™, developed at the University of Toronto, is a palm-sized device that utilizes digital microfluidics (DMF), a technique that allows manipulation of cells and tiny droplets of liquid on an open platform with no moving parts.

"The Smart Well-Plate technology may allow for less expensive screening of chemical libraries and elimination of false leads earlier in the drug discovery process, ensuring a higher success rate for clinical trials focused on cancer," said Frank Stonebanks, Vice-President, Commercialization and Chief Commercial Officer of OICR. "OICR's investment is engineered to move this promising technology closer to commercialization."

High-throughput screening, or HTS, is the universal first step in drug development, allowing chemists and scientists to test biological samples with chemical entities as a starting point for drug design and for understanding a particular biochemical process. It combines robotics with data computing, liquid handling devices, and sensitive detectors that allow researchers to quickly conduct millions of biochemical, genetic or pharmacological tests. The HTS process allows for rapid identification of active compounds, antibodies or genes that modulate a particular biochemical pathway.

In recent years, the introduction of microfluidics has improved the HTS process by miniaturizing cell-based assays. However, the process is limited by the complexity of controlling the reagents simultaneously in interconnected channels. In addition, microfluidics heavily relies upon robotics.

DMF takes the screening concept a step further, by reducing robotics and simplifying reagent handling. It allows dropl
'/>"/>

SOURCE The Ontario Institute for Cancer Research
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3

Related biology technology :

1. Ontario Institute for Cancer Research Announces Enhancements to its Intellectual Property Development and Commercialization Program
2. Ontario Institute for Cancer Research Validates NEBNext(TM) DNA Sample Preparation Reagents from New England Biolabs for use in Next Generation Sequencing
3. Koch Institute for Integrative Cancer Research Dedicated Today
4. Sharpest microscope tip lands Canadas Nanotech Institute in Guinness Book of World Records
5. Weizmann Institute scientists used accelerated evolution to develop enzymes that provide protection against nerve gas
6. Polaris Group and The Ludwig Institute for Cancer Research Ltd Initiate Phase 2 Trial of Amino-Acid Degrading Enzyme, ADI-PEG 20, in Patients with Small Cell Lung Cancer
7. Larta Institute NIH Success Stories Featured in 2011 California Biomedical Industry Report
8. Tufts Launches Institute for Biopharmaceutical Partnerships
9. Salk Institute Celebrates Grand Opening of the Waitt Advanced Biophotonics Center
10. Will Rogers Institute Awards Top Doctor $50,000 for Outstanding Contributions to Lung Research
11. Weizmann Institute scientists used accelerated evolution to develop enzymes that provide protection against nerve gas
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/26/2015)... "In America," the popular news television program that airs ... by legendary film actor James Earl Jones, has announced that ... segment. , Botany is commonly described as the scientific ... a bit more complicated than that. Scientists and other professionals ... from the smallest bacteria known to man to the largest ...
(Date:3/25/2015)... , March 25, 2015 /PRNewswire/ - SQI Diagnostics Inc. ("SQI" ... as a result of recent discussions with certain shareholders ... of the Company, after dealing with certain matters including ... meeting of shareholders on March 26, 2015 (the "Meeting") ... election of directors will take place when the Meeting ...
(Date:3/25/2015)... Md. , March 25, 2015 Accelovance, ... named a finalist for "Best Contract Research Organization" at ... the World Vaccine Congress. This is ... a finalist for the award, winning for "Best Contract ... a "Highly Recommended" distinction in 2013. "We,re ...
(Date:3/25/2015)... 25, 2015 Having added two International ... part of 2014, ITRA Global proudly announced recently the ... Tenant Representative Alliance, based in the United States, is ... and occupiers of commercial real estate. , Saltwood ... in Poland that exclusively advises occupiers of office space, ...
Breaking Biology Technology:SQI Diagnostics Inc. Announces New Nominees to SQI Diagnostics Board and Adjournment of Meeting 2SQI Diagnostics Inc. Announces New Nominees to SQI Diagnostics Board and Adjournment of Meeting 3SQI Diagnostics Inc. Announces New Nominees to SQI Diagnostics Board and Adjournment of Meeting 4SQI Diagnostics Inc. Announces New Nominees to SQI Diagnostics Board and Adjournment of Meeting 5Accelovance Nominated for 2015 Vaccine Industry Excellence (ViE) Awards 2International Organization Expands its Global Reach to Warsaw, Poland 2
... Technology (NIST) has issued a new ruler, and even for ... records. Designed to be the most accurate commercially available "meter ... standard for X-ray diffractionboasts uncertainties below a femtometer. That,s 0.000 ... a neutron. The new ruler is in the form ...
... , , , ... a prospective registry showed good safety in a broad population of patients ... Genous Bio-engineered R stent for ST-elevation myocardial infarction (STEMI). , , ... of major adverse cardiac events (MACE) was 6.7 percent and the rate ...
... SAN DIEGO, Sept. 22 SoluLinK, Inc., a leader ... Catalyst, making conjugation at least 20 times faster than before ... , , Up to now, researchers, conjugation ... poor yields, poor quality and more labor and time consuming ...
Cached Biology Technology:New NIST nano-ruler sets some very small marks 2OrbusNeich's Genous(TM) Bio-Engineered R Stent(TM) is Safe in a Broad Population of Patients with Primary PCI for STEMI 2OrbusNeich's Genous(TM) Bio-Engineered R Stent(TM) is Safe in a Broad Population of Patients with Primary PCI for STEMI 3SoluLinK Introduces Product that Links All Biomolecules Greater Than 20 Times Faster with 100% Yields 2
(Date:3/11/2015)... , Mar. 11, 2015 Research and Markets ... the "Access Control Market by Product, Application & ... report to their offering. , This ... to reach $10.4 billion by 2020, with an estimated ... report covers the products types such as contact cards ...
(Date:3/10/2015)... BOULDER, Colo. , March 10, 2015 ... Space Flight "Personalized Medicine in Human ... Ph.D. and Thomas J. Goodwin , Ph.D. was ... articles of the past two years. Specifically, ... three most downloaded scientific papers published in 2013 and ...
(Date:3/5/2015)... March 5, 2015 In Brazil ... companies already using these solutions and 42 percent planning to ... latter, approximately 25 percent of the companies will be investing ... the majority of companies in the region are currently opting ... hybrid model will command significant attention in the coming years. ...
Breaking Biology News(10 mins):Global Access Control (Cards & Readers, Biometrics, Controllers, Management Software) Market 2015-2020 - Analysis of the $10 Billion Market 2"Personalized Medicine in Human Space Flight" Listed Among Most Influential Papers of 2013 and 2014 2Two of Every Three Brazilian Companies will have Invested in Cloud by 2015, Finds Frost & Sullivan 2Two of Every Three Brazilian Companies will have Invested in Cloud by 2015, Finds Frost & Sullivan 3Two of Every Three Brazilian Companies will have Invested in Cloud by 2015, Finds Frost & Sullivan 4
... in their genes" is a common refrain from scientists when ... and beyond. Up until now, research has focused on ... levels of HDL ("good") cholesterol. But researchers at Albert ... of Psychology of Yeshiva University have found that personality ...
... Preventice, Inc. , a developer of mobile health ... it is the latest to join medical device ... payors that are integrating with Qualcomm Life Inc., ... their 2net™ Ecosystem. (Logo: http://photos.prnewswire.com/prnh/20120417/CG89172LOGO ...
... Diego have discovered that a small dose of a commonly ... affects their ability to recruit their nestmates to otherwise good ... this week,s issue of the Journal of Experimental Biology ... bee-pollinated crops and shed light on one of the main ...
Cached Biology News:'Personality genes' may help account for longevity 2Preventice Expands Options for Wireless Patient Monitoring with Qualcomm Life 2Commonly used pesticide turns honey bees into 'picky eaters' 2
The pCDF Expression System 1 plus Competent Cells contains 10 µg of pET-45b(+) DNA. pET-45b carries an N-terminal His•Tag ® coding sequence that is cleavable with enterokinase as well...
... to Uridine Phosphorylase 1 ( Abpromise ... Antigen: Synthetic peptide: MAATGANAEK AESHNDCPVR LLNPNIAKMK ... corresponding to amino acids 1-99 of Human ... Gene ID: 7378 ...
Request Info...
Syne-1 (N-19)...
Biology Products: