Navigation Links
One-Year Data Show Golimumab Improved Signs and Symptoms In Patients with Psoriatic Arthritis In Phase 3 Study
Date:10/27/2008

uing in the golimumab 100 mg group achieved ACR 20 response. Improvements were also observed in ACR 50 and ACR 70 measures within the same timeframes. Thirty-two percent and 38 percent of patients receiving golimumab 50 mg and 100 mg, respectively, achieved ACR 50 at week 24 compared with 4 percent of patients receiving placebo (P < 0.001). Fifty-seven percent and 53 percent of patients continuing in the respective golimumab dosing groups achieved ACR 50 response through one year. ACR 70 was achieved by 19 percent and 21 percent of patients receiving golimumab 50 mg and 100 mg, respectively, at 24 weeks compared to 1 percent of patients receiving placebo (P < 0.001). These results were sustained through one year with 43 percent of patients receiving golimumab 50 mg and 31 percent of patients receiving golimumab 100 mg achieving ACR 70.

The majority of patients treated with golimumab every four weeks experienced improvements in disease activity as measured by good or moderate Disease Activity Score 28 (DAS 28) response. At week 24, 64 percent and 78 percent of patients receiving golimumab 50 mg and 100 mg, respectively, were DAS 28 responders, compared with 24 percent of patients receiving placebo (P < 0.001). At one year, 93 percent and 86 percent of patients continuing to receive golimumab 50 mg and 100 mg, respectively, were DAS 28 responders.

Golimumab-treated patients also experienced substantial and sustained improvements in psoriatic skin disease through one year. Patients with greater than 3 percent Body Surface Area (BSA) psoriasis skin involvement at baseline were evaluated for Psoriatic Area and Severity Index (PASI) responses. At week 24, 56 percent of patients treated with golimumab 50 mg and 66 percent of patients treated with golimumab 100 mg achieved at least 75 percent improvement in PASI (PASI 75), compared with 1.4 percent of patients receiving placebo (P < 0.001). At one year, 62 percent and 69 percent of patients continuing in the g
'/>"/>

SOURCE Centocor
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7 8 9

Related biology technology :

1. Phase 3 studies show golimumab significantly improved signs and symptoms of rheumatoid arthritis
2. Medarex Receives Milestone Payment for Submission of Regulatory Application Requesting Approval of Golimumab (CNTO 148) in Europe for the Treatment of Rheumatoid Arthritis, Psoriatic Arthritis and Ankylosing Spondylitis
3. Centocor, Inc. and Schering-Plough Submit Application Requesting Approval of Golimumab in Europe for the Treatment of Rheumatoid Arthritis, Psoriatic Arthritis and Ankylosing Spondylitis
4. In-Room Computers and Wall-Mounted Proximity Systems Computer WorkStations Deliver Increased Efficiency; Improved Patient Care
5. Finesse Solutions Launches Improved E-Store for Sensors and Transmitters
6. Kelly Osbourne and International Health Groups Call for Improved Education on Choices and Usage of Contraception
7. Enobia Pharma Presents PreClinical Data Showing ENB-0040 Significantly Improved Survival and Healed Skeletal Manifestations of Severe Hypophosphatasia in Mice
8. Improved culture system for hepatitis C virus infection
9. Pharmacy Students Taught Improved Medication Adherence and Holistic Health Services Through Program Incorporating InforMedixs Med-eXpert(TM) System
10. Sensitivity Enhancements to Monograms Trofile(TM) Assay Demonstrate Improved Power to Select Patients for CCR5 Antagonist Therapy
11. China Kangtai Cactus Biotech Announces Improved Milk Production in Cows From Companys Cactus Cattle Feed
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/26/2014)... 26, 2014 2014 Deep Research ... in-depth research report on the Global Palmitic Acid ... Palmitic Acid, basic information, including definition, classification, application, ... news analysis, etc. , For international and ... Acid market in China and other countries ...
(Date:11/26/2014)... MINNEAPOLIS , Nov. 25, 2014 Bio-Techne ... it has appointed Robert Gavin to serve ... of the Protein Platforms Division.  Mr. Gavin will be ... business segment, which includes the ProteinSimple business acquired in ... San Jose, California -based ProteinSimple ...
(Date:11/26/2014)... , Nov. 25, 2014  Roka Bioscience, Inc. (NASDAQ: ... providing advanced testing solutions for the detection of foodborne pathogens, ... at the Piper Jaffray  26 th Annual Healthcare Conference ... be held at The New York Palace in ... presentation, material information concerning the Company, its operations, strategies and ...
(Date:11/24/2014)... November 24, 2014 Five American ... Rashid Al Maktoum Awards for Medical Sciences", in its ... United Arab Emirates , on 15 December 2014. ... The Carter Center which won the Hamdan ... involved in numerous programs that aim to improve health ...
Breaking Biology Technology:Palmitic Acid Industry Global 2014 Analysis & 2020 Forecasts on Market data, Statics, Development Now at ReportsnReports.com 2Palmitic Acid Industry Global 2014 Analysis & 2020 Forecasts on Market data, Statics, Development Now at ReportsnReports.com 3Bio?Techne Announces Appointment Of Robert Gavin As Leader Of New Protein Platforms Division 2Bio?Techne Announces Appointment Of Robert Gavin As Leader Of New Protein Platforms Division 3Roka Bioscience to Present at the Piper Jaffray Healthcare Conference 2Five US Winners Among Recipients of Hamdan Medical Awards 2
... been used to dye the Chicago River green on St. ... at crime scenes. And now researchers at Northwestern University have ... The useful tool is the dye fluorescein, and Jiaxing ... McCormick School of Engineering and Applied Science, and his research ...
... ... personal emergency situations when parents leave behind their children at charity institutions ... recent case revealed that at least one couple left behind two children ... suspect abandonned children might be siblings, how can you find out? Although ...
... , , , BOTHELL, Wash., Dec. 23 BioLife Solutions, ... marketer of biopreservation tools for cells, tissues, and organs, today ... systems and GMP production facility in Bothell, Washington by BSI ... an international standard for quality systems supporting the design, development, ...
Cached Biology Technology:An easy way to see the world's thinnest material 2Paternity Testing Without Father and Mother? The German Company bj-diagnostik Investigates that Two babies Separately Left at Charity Institution are Siblings 2Paternity Testing Without Father and Mother? The German Company bj-diagnostik Investigates that Two babies Separately Left at Charity Institution are Siblings 3BioLife Solutions Achieves ISO 13485 Quality Management Systems Certification 2BioLife Solutions Achieves ISO 13485 Quality Management Systems Certification 3
(Date:11/4/2014)... research study examining only marketing directed at children ... restaurants has found that the majority of black, ... such marketing tactics. , Authored by Arizona State ... study is the first to examine the use ... of fast food restaurants and its relationship to ...
(Date:11/4/2014)... Nov. 4, 2014   Neurotechnology , a ... that the latest version of its fingerprint matching ... Ongoing MINEX evaluation organized by NIST. The ... using the INCITS 378 fingerprint standard template format. ... public tenders in the United States ...
(Date:11/3/2014)... 2014  NeuroSigma ® , Inc. (NeuroSigma), a ... focused on commercialization of its non-invasive ... of neurological and neuropsychiatric disorders, announced today that ... a Notice of Allowance for Mexican Patent Application ... NeuroSigma and the Regents of the University of ...
Breaking Biology News(10 mins):Fast food marketing for children disproportionately affects certain communities 2Fast food marketing for children disproportionately affects certain communities 3Neurotechnology Places Second in Ongoing MINEX Ranking for Fingerprint Matching Algorithms 2Neurotechnology Places Second in Ongoing MINEX Ranking for Fingerprint Matching Algorithms 3NeuroSigma Receives Notice of Allowance from the Mexican Institute of Industrial Property Covering Subcutaneous Trigeminal Nerve Stimulation (sTNS) 2NeuroSigma Receives Notice of Allowance from the Mexican Institute of Industrial Property Covering Subcutaneous Trigeminal Nerve Stimulation (sTNS) 3
... LOS ANGELES, Sept. 10 Cogent Systems (Nasdaq:,COGT) ... today announced that,they have reached an agreement to ... fingerprint identification technology.,The agreement is subject to negotiation ... of the agreement, Northrop Grumman has agreed to ...
... Currently in Use, Including Large Scale, Election Enrollment, Retail, ... ... Demonstrated, WALL, N.J., Sept. 10 BIO-key International,Inc. ... public safety, announced today that the company,is showcasing a variety of ...
... WASHINGTON, Sept. 12 J. Michael McConnell, Director ... Secretary of Defense,for Intelligence will provide valuable insights ... vision for implementing the United States,Intelligence Community 100 ... the Conference: The Office of the Director ...
Cached Biology News:Cogent Systems and Northrop Grumman Reach Agreement to Settle Automated Fingerprint Identification Technology Suit and Create Strategic Alliance 2Cogent Systems and Northrop Grumman Reach Agreement to Settle Automated Fingerprint Identification Technology Suit and Create Strategic Alliance 3BIO-key(R) International to Showcase Deployed Biometric Security Applications at 2007 Biometric Technology Expo 2BIO-key(R) International to Showcase Deployed Biometric Security Applications at 2007 Biometric Technology Expo 3
Oct 2 Immunogen: Full length human protein. Storage: -20 C, Avoid Freeze/Thaw Cycles...
Mouse monoclonal [3B6] to HSV1 + HSV2 ICP5 Major Capsid Protein ( Abpromise for all tested applications)....
Mouse monoclonal [2Q2147] to Aequorin ( Abpromise for all tested applications)....
p21 Ras Immunogen: Recombinant C-H-ras p21(val-12). Storage: 4 C...
Biology Products: