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Oncothyreon Highlights for 2009
Oncothyreon's corporate highlights for the year 2009 to date include the
following:
- Expansion of the Phase 3 development program for Stimuvax with the
initiation of the STRIDE trial in hormone receptor-positive, locally
advanced, recurrent or metastatic breast cancer by Oncothyreon's
partner Merck KGaA. Stimuvax is also being studied in the Phase 3
START trial in non-small cell lung cancer (NSCLC).
- Presentation of long-term data for Stimuvax in NSCLC at the
International Association for the Study of Lung Cancer's 13th World
Conference on Lung Cancer. The data involved 16 patients who received
treatment with Stimuvax for between 2 and 8.2 years as part of the
Phase 2b trial in patients with stage IIIb/IV NSCLC. As of the time
of data analysis in April 2009, 10 of the 16 studied patients were
alive without evidence of disease progression, of whom eight
continued to receive therapy with Stimuvax after 6.3 to 8.2 years.
The remaining two living patients discontinued Stimuvax therapy after
2.4 and 5.8 years, respectively, and were without evidence of disease
progression.
- Presentation of preliminary results from the Phase 1 trial of PX-866,
an inhibitor of PI-3 kinase, at the American Society of Clinical
Oncology. The data demonstrated inhibition of PI-3 kinase activity at
low doses, as well as stabilization of disease in six of 24 patients
with previously progressive d
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